Explore Senior Machine Learning Engineer opportunities at companies building intelligent products and data-driven systems. These experienced professionals design, develop, and deploy machine learning solutions, turning research and business needs into reliable applications. Ladders features vetted professional jobs paying $100,000 or more, helping you find roles aligned with your skills and career goals.
Senior Machine Learning Engineers typically own substantial parts of the machine learning lifecycle, from defining problems and preparing data to training models, deploying services, and monitoring performance. They collaborate with data scientists, software engineers, product teams, and business stakeholders to deliver solutions that are accurate, scalable, maintainable, and useful.
Employers often seek strong programming skills, especially in Python, along with experience in machine learning frameworks, statistical methods, and software engineering practices. Familiarity with cloud platforms, distributed computing, MLOps, model evaluation, and production deployment can be valuable. Senior roles may also call for technical leadership, mentoring, and the ability to explain complex findings to cross-functional teams.
Senior Machine Learning Engineers work across industries such as technology, finance, healthcare, retail, and logistics. Depending on the organization, the role may focus on generative AI, recommendation systems, search, computer vision, natural language processing, forecasting, or fraud detection. Experienced engineers can grow into staff or principal engineering roles, technical management, or specialized AI leadership positions.
Search Senior Machine Learning Engineer jobs on Ladders to discover vetted professional opportunities with salaries of $100,000 or more. Compare roles by responsibilities, required expertise, and growth potential, then identify openings that match your experience in building and operating machine learning systems.
Applied AI/ML Engineer (TS/SCI)
$180K - $214K *
Innovate solutions by leveraging AI/ML to tackle complex geospatial intelligence challenges. Collaborate across teams to develop, implement, and evaluate cutting-edge models, ensuring effective data i...
5 days ago
$110K - $130K *
Lead the charge in developing and optimizing production software and AI systems on cloud infrastructure, ensuring reliability, security, and cost-effectiveness while collaborating with cross-functiona...
6 days ago
Staff Machine Learning Engineer
$205K - $240K *
Transform global trade data into actionable insights by leading the development of advanced machine learning models and systems. Collaborate with cross-functional teams to enhance risk and compliance...
1 week ago
Staff Machine Learning Engineer
$205K - $240K *
Join a team that's shaping the future of global trade through AI. Lead the development of advanced machine learning systems that transform trade data into real-time compliance and risk decisions for g...
1 week ago
Staff Machine Learning Engineer
$205K - $240K *
Shape the future of global trade by leading AI-driven systems that transform vast trade data into real-time compliance and risk decisions, while mentoring engineers and collaborating across teams to i...
1 week ago
Staff Machine Learning Engineer
$205K - $240K *
Shape the future of global trade by leading AI-driven systems that transform trade data into real-time compliance and risk decisions. Collaborate with cross-functional teams to innovate and enhance ag...
1 week ago
Senior Staff Software Engineer, AI Runtime
$228K - $342K *
Unlock potential by driving AI Runtime's architecture and shaping the future of AI training infrastructure. Lead technical direction, enhance developer experience, and tackle complex multi-node traini...
5 days ago
Principal Software Development Engineer, ML-Powered Flight Search
$231K - $323K *
Drive the architectural vision and delivery of complex software solutions, optimizing performance and security across multiple domains while mentoring engineering teams and integrating AI/ML solutions...
2 weeks ago
$150K - $180K *
Join a team that's revolutionizing healthcare by building scalable AI infrastructure that powers advanced healthcare solutions while ensuring top-tier reliability and performance in critical environme...
Reposted 6 days ago
$120K - $145K *
Join a team that's shaping dynamic pricing solutions by developing algorithmic pay models that enhance courier earnings fairness and marketplace efficiency, collaborating across product and engineerin...
1 week ago
$110K - $130K *
Shape the future of AI in healthcare by developing scalable solutions using Python, LangGraph, and LangChain. Collaborate with a high-performing team to enhance intelligent workflows and drive innovat...
Today
$110K - $130K *
Advance the future of AI in healthcare by developing intelligent workflows and automation. Collaborate with a high-performing team to enhance enterprise AI platforms using cutting-edge technologies li...
Today
$110K - $130K *
Join a dynamic team to develop and enhance AI solutions using Python, LangGraph, and LangChain. Collaborate on innovative projects that drive intelligent workflows and automation across healthcare, le...
Today
$110K - $130K *
Optimize enterprise AI solutions by developing intelligent workflows and conversational experiences. Collaborate with a high-performing team to enhance automation and drive innovation across multiple...
Today
$110K - $130K *
Unlock potential by developing cutting-edge AI solutions that enhance enterprise workflows and conversational experiences. Collaborate with a high-performing team to drive innovation and impact across...
Today
Frontier Agent Engineering Manager, Enterprise
$227K - $325K *
Lead the charge in deploying cutting-edge AI solutions for enterprise clients, bridging technical expertise and customer needs. Manage a team to architect and implement tailored AI systems, ensuring s...
Today
Senior Software Engineer, GPU Code Generation for Machine Learning Inference
$152K - $287K *
Drive innovation in AI inference by developing high-performance GPU software. Collaborate with experts to optimize code generation and enhance generative AI models, ensuring efficiency across diverse...
4 days ago
$110K - $130K *
Transform enterprise AI solutions by developing intelligent workflows and automation. Collaborate with a high-performing team to enhance conversational experiences and drive innovation across multiple...
Today
$130K - $155K *
Transform AI capabilities by building reliable systems that empower autonomous agents. In this hands-on role, you'll implement core infrastructure, ensuring seamless integration and operational excell...
2 weeks ago
Staff Software Engineer - Customer Facing Applied AI
$158K - $248K *
Lead the charge in shaping cutting-edge AI solutions for clients by setting the technical direction, building innovative systems, and guiding product integration, all while mentoring engineers and inf...
4 weeks ago
Machine Learning Engineer Graduate (TikTok-Data-Search-Search Quality) - 2027 Start
$128K - $256K *
Innovate within a dynamic team to enhance search systems and user experiences. Leverage machine learning and cutting-edge technologies to tackle complex challenges, personalize search results, and del...
Reposted 3 weeks ago
$125K *
Lead data-driven initiatives by aggregating and analyzing client data to provide actionable insights. Collaborate with cross-functional teams to optimize business strategies and enhance product perfor...
Today
Sr. Computer Vision/ML Scientist
$138K - $165K *
Drive innovative applied research in computer vision and ML, tackling complex visual understanding challenges across industries. Lead projects from concept to deployment, mentoring junior scientists w...
1 week ago
Senior Systems Engineer - AI Infrastructure
$150K - $210K *
Join a team that's building high-performance distributed GPU training infrastructure. You'll design and implement systems software, ensuring reliability and efficiency in complex, fault-tolerant envir...
2 weeks ago
Senior Data Scientist (Onsite)
$150K - $200K *
Lead the charge in developing innovative data science solutions, collaborating with experts to address complex challenges. Engage directly with clients to translate technical concepts into actionable...
3 weeks ago
What does a Senior Machine Learning Engineer do?
A Senior Machine Learning Engineer builds and operates machine learning systems, including preparing data, developing and evaluating models, deploying them into production, and monitoring their performance. They often guide technical decisions and collaborate with product, data, and engineering teams.
What qualifications are commonly required for Senior Machine Learning Engineer jobs?
Requirements vary, but commonly include strong programming ability, machine learning and statistical knowledge, experience with production software, and familiarity with tools or frameworks used to train and deploy models. Senior positions may also require cloud, MLOps, system design, and mentorship experience.
What industries hire Senior Machine Learning Engineers?
Technology, finance, healthcare, retail, logistics, and many other sectors hire Senior Machine Learning Engineers to develop applications such as recommendations, fraud detection, forecasting, language technologies, and computer vision.
How can I find Senior Machine Learning Engineer jobs paying $100,000 or more?
Use Ladders to explore vetted professional openings with salaries of $100,000 or more. Review each listing's responsibilities, qualifications, and compensation details to find roles that fit your background and goals.