Senior Clinical Trial Manager Jobs

Explore senior clinical trial manager jobs with Ladders, where you can find vetted professional opportunities paying $100,000 or more. Senior Clinical Trial Managers guide clinical studies from planning through closeout, helping ensure trials are conducted ethically, efficiently, and in compliance with applicable regulations and protocols.

What Senior Clinical Trial Managers Do

These leaders oversee trial operations, timelines, budgets, vendors, and study teams. Responsibilities may include coordinating site activation and enrollment, monitoring study progress, managing risks and deviations, reviewing documentation, and communicating updates to sponsors, investigators, and internal stakeholders. The scope of a role varies by employer, therapeutic area, and development phase.

Skills and Experience Employers Seek

Employers commonly look for substantial clinical research experience, strong project and people-management skills, and familiarity with Good Clinical Practice (GCP), clinical trial regulations, and quality systems. Success also depends on clear communication, sound judgment, attention to detail, and the ability to resolve issues across a complex, cross-functional environment. Some positions favor experience with particular therapeutic areas, global studies, or clinical operations platforms.

Career Paths and Opportunities

Senior Clinical Trial Managers work for pharmaceutical and biotechnology companies, contract research organizations (CROs), and other clinical research organizations. Depending on experience and organizational structure, this role can lead to director-level positions in clinical operations or broader clinical development leadership. Browse current opportunities to compare responsibilities, qualifications, work arrangements, and compensation.

Find Senior Clinical Trial Manager Jobs on Ladders

Use Ladders to discover vetted senior clinical trial manager openings with salaries of $100,000 or more. Review each listing for its location, compensation details, required experience, and study responsibilities to find opportunities aligned with your expertise and career goals.

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$110K - $130K *

Join a team that's dedicated to ensuring clinical study integrity through comprehensive monitoring and training. Contribute to the success of complex trials while collaborating with passionate profess...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to ensuring clinical study integrity through comprehensive monitoring and training. Collaborate with experts to support innovative trials, enhancing patient safety and tre...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic team to ensure clinical study integrity through on-site monitoring, training, and regulatory support. Collaborate with investigators and staff to maintain high standards in complex tria...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion clinical excellence by conducting comprehensive monitoring visits, ensuring investigational sites meet study requirements, and training staff to uphold the highest standards throughout the cl...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Lead the charge in managing complex Life Sciences programs, ensuring alignment with customer commitments. Drive delivery across teams, proactively addressing risks and building a PMO as the business s...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead advanced technical consulting in reinsurance, collaborating with Brokers and clients to manage risk, mentor colleagues, and enhance operational processes while delivering exceptional client servi...

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Drive advanced technical insight and guidance in complex reinsurance scenarios. Collaborate with Brokers and clients to manage risk, mentor colleagues, and enhance operational improvements while repre...

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$165K - $175K *

Lead the charge in managing global clinical trials, overseeing cross-functional teams, and ensuring project objectives are met across multiple therapeutic areas while driving operational excellence an...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Staffing

$88K - $105K *

Lead the charge in managing client relationships and program performance, ensuring timely delivery of medications. Oversee budgets, facilitate communication between stakeholders, and drive successful...

North Carolina, USRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $135K *

Lead the charge in managing clinical trial activities, ensuring compliance with GCP and regulations while optimizing timelines and budgets. Collaborate with cross-functional teams and external partner...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $135K *

Join a team that's dedicated to managing clinical trials efficiently, ensuring compliance with regulations and standards. Collaborate with cross-functional teams to drive project success while maintai...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $214K *

Advance your career by leading large-scale Lifecycle Safety projects, ensuring service excellence and customer satisfaction. Collaborate cross-functionally to drive strategic initiatives and enhance o...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Oversee the clinical study lifecycle at multiple sites, ensuring compliance with protocols and regulatory standards. Collaborate with cross-functional teams to achieve project milestones effectively w...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Engage with diverse teams to oversee clinical study sites, ensuring compliance and efficient study conduct through proactive problem-solving and collaboration with site personnel and internal stakehol...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $138K *

Join a dynamic team to drive clinical trial success in Oncology, fostering strong investigator relationships and strategic enrollment strategies. Leverage your expertise to enhance trial execution and...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $150K *

Lead the charge in enhancing risk management strategies, ensuring alignment with best practices and facilitating seamless integration across projects. Collaborate with diverse stakeholders to proactiv...

Toronto, ONIn-Person

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $150K *

Tackle risk management challenges by leading innovative practices that enhance service delivery, ensure project compliance, and foster collaboration among stakeholders while managing complex projects...

Vancouver, BCIn-Person

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead comprehensive risk management strategies for major projects, enhancing service delivery and stakeholder collaboration while ensuring adherence to policy and frameworks to minimize risk exposure a...

Edmonton, ABIn-Person

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$170K - $204K *

Manage pharmacovigilance activities to ensure patient safety across clinical programs. Collaborate with cross-functional teams to uphold compliance and operational excellence while leading a growing t...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Manage clinical study progress by monitoring sites, ensuring compliance with protocols and regulations, and fostering relationships with investigators. Contribute to dermatology and rheumatology proje...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Elevate clinical research by monitoring trials, ensuring compliance with protocols and regulations. Collaborate with investigators to achieve study goals in dermatology and rheumatology, while working...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$143K - $185K *

Unlock potential by leading clinical data management for innovative cell therapy studies. Collaborate cross-functionally to ensure data integrity and compliance while managing teams and external partn...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $145K *

Join a team that's dedicated to empowering your career as you manage cost strategies, oversee project budgets, and foster strong client relationships. Collaborate with diverse experts while driving im...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$108K - $145K *

Join a dynamic team as you manage project costs, drive strategic initiatives, and foster relationships. Leverage your expertise in cost management to deliver value and support growth while mentoring o...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$95K - $115K *

Champion your career by joining a dynamic team where you'll manage costs, analyze bids, and drive project success. Collaborate with industry leaders to enhance your skills and contribute to strategic...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What does a Senior Clinical Trial Manager do?question toggle

    A Senior Clinical Trial Manager leads the operational delivery of clinical studies, coordinating timelines, budgets, sites, vendors, and cross-functional teams while helping maintain protocol, quality, and regulatory compliance.

  • What qualifications are typically required for Senior Clinical Trial Manager jobs?question toggle

    Requirements vary, but employers often seek significant clinical research or clinical operations experience, experience managing studies or teams, and knowledge of GCP and applicable clinical trial regulations. Some roles require therapeutic-area or global-trial expertise.

  • Where do Senior Clinical Trial Managers work?question toggle

    They may work for pharmaceutical and biotechnology companies, CROs, and other organizations involved in clinical research. Roles can support studies across a range of therapeutic areas and development phases.

  • How much do Senior Clinical Trial Managers earn?question toggle

    Compensation varies based on employer, location, experience, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more; check individual listings for salary and compensation details.

  • How can I find Senior Clinical Trial Manager jobs paying $100,000 or more?question toggle

    Browse Senior Clinical Trial Manager listings on Ladders and review each posting’s salary information, qualifications, location, and responsibilities to identify opportunities that fit your background.