Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$100K - $130K *

Shape the future of mental health services by leading and developing psychotherapy clinicians. Enhance professional growth while ensuring clinical integrity and compliance through strategic oversight...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by leading a dynamic Counseling Department, overseeing clinical and administrative functions, and enhancing client care through innovative program development and staff supervision...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Optimize patient access services by leading strategic operations and enhancing compliance. Drive performance, foster teamwork, and ensure exceptional service delivery while maintaining fiscal integrit...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Advance operational excellence by leading day-to-day functions, managing staff, and driving strategic goals to ensure timely production and delivery while optimizing costs and enhancing customer satis...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$140K - $187K *

Drive regulatory strategy and execution for global programs, collaborating with cross-functional teams to ensure compliance and timely submissions. Lead regulatory packages and manage health authority...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$201K - $236K *

Lead the charge in optimizing sales operations by driving strategy, forecasting, and process improvements. Collaborate with cross-functional teams to enhance productivity and ensure the sales organiza...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $230K *

Drive impactful business outcomes by leading analytics teams, extracting insights from complex data, and consulting with clients to optimize marketing strategies. Foster collaboration and operational...

3 days ago

  •   11 - 15 years exp.  •   Media

$120K - $230K *

Lead the charge in delivering actionable insights through advanced analytics. Oversee multiple teams, drive operational excellence, and consult with clients to optimize marketing strategies and achiev...

3 days ago

  •   11 - 15 years exp.  •   Media

$120K - $230K *

Drive impactful business outcomes by leading analytics initiatives, consulting with clients, and mentoring teams. Shape audience strategies and measurement plans while staying ahead of industry trends...

1 week ago

  •   11 - 15 years exp.  •   Media

$120K - $230K *

Transform business outcomes by leading analytics strategies, consulting with clients, and mentoring teams. Drive innovation in audience insights and measurement, while fostering impactful client relat...

1 week ago

  •   11 - 15 years exp.  •   Media

$120K - $230K *

Shape impactful analytics strategies by consulting with clients, leading audience identification, and mentoring teams to drive measurable business outcomes and innovation in marketing analytics...

1 week ago

  •   11 - 15 years exp.  •   Media

$136K - $214K *

Lead the charge in optimizing revenue operations by managing a dynamic team, enhancing forecasting processes, and ensuring data integrity across systems. Collaborate closely with sales leadership to d...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$180K - $243K *

Lead the charge in clinical development and medical affairs, guiding a global team to shape strategic evidence and product strategies. Drive innovation and collaboration across departments to enhance...

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$120K - $130K *

Elevate nursing operations by leading a dynamic clinical team, driving quality care, and ensuring survey readiness. Collaborate with Unit Managers to foster a supportive environment and develop nursin...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Advance laboratory services by providing leadership and operational support. Oversee daily operations, ensure compliance, manage budgets, and foster a culture of quality and continuous improvement whi...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $200K *

Shape the future of biotechnology by driving growth and forging strategic partnerships. As a leader, you’ll identify new opportunities and enhance market presence while collaborating with key stakehol...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Oversee outpatient operations to ensure high-quality, cost-effective medical services. Lead integration between clinics and procedural spaces, enhancing patient access and physician productivity while...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $236K *

Empower pharmacy operations by leading strategic initiatives that enhance affordability, health outcomes, and member experiences. Collaborate across teams to drive operational excellence and scalable...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$191K - $239K *

Innovate high-quality medical content to enhance strategic communication across Medical Affairs. Collaborate cross-functionally to provide accurate, timely scientific insights supporting informed deci...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$191K - $239K *

Lead the charge in crafting impactful medical content and strategic communications, ensuring scientific accuracy and cross-team collaboration to enhance patient-focused outcomes in a compliant environ...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$191K - $239K *

Pioneer innovative medical content strategies, driving effective cross-functional partnerships to deliver precise, timely scientific information that enhances understanding of therapeutic areas and su...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $338K *

Help us advance women's health through innovative clinical trial strategies, where you will conduct, support, and report on global studies for cutting-edge compounds, ensuring adherence to regulatory...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $338K *

Shape the future of women's health by leading global clinical trials, collaborating with cross-functional teams, and ensuring safety and regulatory compliance in innovative drug development...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion the Behavioral Health Program, ensuring quality clinical services, compliance, and effective crisis management while training and overseeing staff, and coordinating with multiple departments...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$300K - $360K *

Strategize the commercial operations for our groundbreaking rare disease therapy. Lead infrastructure development and enhance sales forecasting while ensuring efficient cross-department collaboration...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.