Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$213K - $304K *

Join a team that's advancing clinical development in oncology. Collaborate with experts to design and execute trials, ensuring compliance and driving innovative strategies for new therapies. Make a si...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$225K - $250K *

Lead strategic initiatives in analytical operations, enhancing data-driven decision-making across departments. Oversee project management and HCC teams, driving efficiency and optimizing workflows to...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$225K - $250K *

Innovate operational excellence by leading analytical initiatives that enhance financial decision-making and drive performance across departments, ensuring effective data utilization and workflow opti...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $140K *

Join a team that's transforming healthcare through visionary philanthropy. As a key contributor, you'll cultivate relationships and drive fundraising efforts to support innovative research and patient...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Transform risk management practices by leading initiatives that enhance patient safety and compliance. Collaborate with clinical teams to develop effective policies and ensure a secure environment for...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$280K - $311K *

Optimize safety evaluations within our Drug Safety team to drive innovative strategies for monitoring and managing clinical risks, ensuring compliance and maintaining high-quality standards in pharmac...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Deliver innovative omnichannel experiences by leading strategy design, optimizing customer journeys, and leveraging data insights. Collaborate with teams to align brand purpose with user needs, ensuri...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $135K *

Drive excellence in nursing leadership by overseeing operations and ensuring high-quality, patient-centered care in a dynamic substance use disorder treatment environment. Collaborate with a multidisc...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $128K *

Optimize clinical contract processes and program development through effective collaboration, leveraging expertise in healthcare regulations, behavioral health services, and compliance to enhance oper...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$227K - $398K *

Transform the Quality Compliance landscape by leading strategic initiatives, ensuring regulatory adherence, and fostering a culture of continuous improvement across GxP activities. Collaborate with cr...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Join a team that's shaping the future of clinical research by leading innovative development programs. Drive the design, execution, and analysis of clinical trials, ensuring high-quality data supports...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$91K - $93K *

Elevate the performance of our Opiate Treatment Program by leading clinic operations, driving compliance, managing staff, and enhancing patient care. Collaborate with key stakeholders to support growt...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$189K - $316K *

Lead the charge in developing innovative clinical strategies that drive the success of asset-level projects. Collaborate cross-functionally to enhance patient outcomes through pioneering research and...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$189K - $316K *

Advance your career by leading clinical development initiatives in aging research; drive scientific strategy and multidisciplinary collaboration to deliver innovative medicines that enhance patient ou...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $199K *

Deliver strategic oversight and enhance services in Intake and Clinical departments, directly impacting employee morale and development while ensuring high-quality consumer service and operational eff...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$250K - $325K *

Lead the charge in advancing clinical AI and care delivery systems, guiding a high-performing engineering team to innovate solutions that streamline clinician workflows and enhance patient care throug...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $325K *

Join a cutting-edge healthcare tech team to lead engineering in AI and clinical systems. Drive innovation by managing teams, optimizing workflows, and collaborating across functions to transform care...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform the future of surgical education by leading the Surgical Proficiency Laboratory. Drive innovative curricula, manage operations, and secure funding to enhance training for residents and fello...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower excellence in patient care by overseeing unit operations, fostering collaboration, and implementing strategies to enhance quality outcomes and patient experience while ensuring compliance with...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that leads clinical trials from start to finish, ensuring compliance and quality. Manage relationships with CROs and vendors while overseeing timelines and budgets in a collaborative, fast...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Staffing

$293K - $358K *

Champion clinical trial execution in oncology, ensuring patient safety and protocol adherence while collaborating within a high-caliber cross-functional team and shaping future drug development strate...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in enhancing clinical program operations by managing staff, improving workflows, and ensuring quality assurance. Collaborate with teams to develop and implement effective strategies th...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$175K - $210K *

Elevate your career by leading Clinical Pharmacology initiatives, driving strategic drug development, and collaborating with cross-functional teams to achieve impactful results in a dynamic environmen...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead key clinical trial operations, from start-up to enrollment, ensuring regulatory compliance and data integrity while collaborating closely with investigators and managing resources effectively to...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Lead the operational success of multiple ophthalmology practices, focusing on strategic planning, performance metrics, and team engagement to drive growth and enhance patient satisfaction across the M...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.