Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$180K - $220K *

Lead the transformation of clinical operations by strategically overseeing oncology programs, ensuring timely and budget-conscious execution while harnessing AI for operational efficiency from startup...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$181K - $236K *

Champion clinical operations by leading strategic execution of clinical studies, ensuring compliance, quality, and timely delivery. Manage cross-functional teams and oversee vendor partnerships to ach...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the execution of early-phase clinical trials in obesity, ensuring compliance and timely delivery. Collaborate cross-functionally to advance innovative therapies while managing vendors and operati...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$211K - $264K *

Join a dynamic team as a Clinical Operations leader, overseeing clinical trials and CRO management. Drive strategic planning, ensure compliance, and mentor staff while managing timelines and budgets f...

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the charge in optimizing clinical operations by managing research staff, ensuring compliance, and enhancing study performance. Collaborate across departments to meet milestones and deliver qualit...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$185K - $205K *

Shape the future of clinical operations by leading strategic initiatives, optimizing workflows, and driving cross-functional projects. Collaborate with senior leaders to enhance efficiency and ensure...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$185K - $205K *

Lead the charge in optimizing clinical operations and strategy, driving cross-functional projects from ideation to implementation. Collaborate with senior leaders to enhance workflows, ensure complian...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Transform clinical operations by leading teams to enhance patient care, streamline workflows, and ensure compliance. Collaborate with physicians and staff to drive quality improvements and optimize re...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $160K *

Oversee the operational planning and execution of clinical trials, ensuring compliance with regulatory standards while managing cross-functional teams to meet project timelines, budgets, and quality o...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$290K - $308K *

Lead the charge in global clinical operations for cutting-edge T-cell therapies. Oversee strategic planning, execution, and stakeholder management while nurturing and developing a thriving Clinical Op...

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Oversee the execution of clinical programs, ensuring compliance with timelines, budgets, and quality standards. Collaborate with cross-functional teams to enhance clinical trial efficiency and effecti...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$176K - $220K *

Transform clinical development with strategic leadership to execute Phase 3 trials. Drive operational excellence, manage cross-functional collaboration, and shape innovative processes to elevate globa...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate healthcare delivery by leading operational and strategic initiatives across mental health and diagnostic services, ensuring compliance, quality, and patient-centered care while optimizing perf...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Champion operational excellence in clinical trials by leading a team of Clinical Trial Managers. Drive strategic initiatives, ensure compliance, and enhance sponsor relationships while delivering stud...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$250K - $311K *

Shape the future of clinical operations by leading strategy, delivery, and quality for innovative trials. Drive team development and operational excellence while collaborating with cross-functional pa...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$231K - $264K *

Unlock potential by leading strategic initiatives to enhance clinical operations, drive operational excellence, and foster collaboration across cross-functional teams while optimizing processes and re...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead and innovate care delivery operations, ensuring exceptional patient experiences and efficient management of multiple clinics and hospital services. Collaborate with diverse teams to align activit...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Empower residents' health by providing clinical leadership and supervision in a skilled nursing facility. Ensure compliance with medical regulations, oversee quality improvement initiatives, and manag...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$155K - $259K *

Elevate your career by leading integrated optimization programs that enhance clinical, operational, and financial performance for healthcare clients. Drive measurable outcomes while managing diverse m...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$225K - $245K *

Drive clinical operations for oncology studies, translating strategies into actionable plans. Lead teams, manage resources, and ensure quality delivery while collaborating across functions to enhance...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $100K *

Transform clinical operations by leading patient care delivery, optimizing workflows, and ensuring regulatory compliance. Drive educational excellence and support financial sustainability within a dyn...

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Lead and optimize clinical operations, ensuring effective scheduling and coordination. Drive team development, streamline processes, and leverage data to enhance performance in a dynamic healthcare en...

Today

  •   5 - 7 years exp.  •   Healthcare

$247K - $322K *

Lead the charge in advancing clinical operations for late-stage cardiovascular studies. Oversee cross-functional teams, manage budgets, and drive innovative strategies to enhance patient outcomes and...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.