Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Director, Project Management Office
$110K - $130K *
Transform project delivery by leading a high-performing PMO, optimizing processes, and ensuring compliance with best practices while collaborating with executive leaders to meet client needs and drive...
3 weeks ago
Clinical Director, Clinical Research, Hematology
$255K - $402K *
Champion innovation in oncology research as you lead clinical trials from design to execution. Collaborate cross-functionally while ensuring scientific integrity and regulatory compliance to propel dr...
Reposted 4 weeks ago
$112K - $193K *
Lead the charge in managing multiple health centers, driving strategic growth, patient satisfaction, and operational excellence while overseeing financial performance and team development in a dynamic...
2 weeks ago
$110K - $130K *
Transform clinical operations by leading a dynamic team in Radiation Oncology. Oversee facility management, ensure regulatory compliance, and drive patient-centered care while enhancing operational pe...
1 week ago
Senior Manager, Clinical Learning Delivery & Execution
$103K - $140K *
Drive the operational strategy and execution of clinical training programs, ensuring effective onboarding and continuous improvement across diverse teams. Lead a proactive team to enhance workforce re...
1 week ago
$80K - $95K *
Shape the future of clinic operations by leading a dedicated team to enhance performance, improve systems, and drive impactful results for clients and families, while fostering a culture of growth and...
4 weeks ago
$75K - $85K *
Lead the delivery of addiction recovery and mental health services, overseeing treatment programs and staff supervision, while ensuring compliance with policies and exceptional care for clients and fa...
4 weeks ago
Director, Clinical Research (Lingo)
$172K - $344K *
Lead strategic planning and execution of clinical research programs, managing multiple studies and partnerships with CROs and clinical sites to ensure adherence to regulatory standards and quality out...
Reposted 4 days ago
Director, Biometrics Strategy and Business Development
$125K - $150K *
Drive revenue growth and strategic partnerships in biometrics services, focusing on client relationships and market strategy. Collaborate with teams to deliver innovative solutions and position the or...
1 week ago
Director of Operations - Pathology Services
$107K - $171K *
Champion the operational excellence of pathology services across divisions, ensuring effective management, compliance, and quality improvement. Lead strategic initiatives, optimize workflows, and enha...
6 days ago
$80K - $95K *
Shape the future of addiction treatment by leading a dedicated outpatient team. Drive operational excellence, foster clinician development, and ensure evidence-based care in a supportive environment f...
Today
Associate Director, Clinical Science
$180K - $240K *
Empower clinical development by leading scientific strategy for BHB-1893, driving protocol design, data analysis, and cross-functional collaboration to ensure successful Phase 3 execution and regulato...
1 week ago
Associate Director, Clinical Science
$180K - $240K *
Lead scientific strategy for clinical development of BHB-1893, collaborating with cross-functional teams to ensure data integrity and regulatory compliance. Drive protocol design, data analysis, and e...
1 week ago
Clinical Operations Program Manager
$85K - $100K *
Drive operational excellence by leading clinical education initiatives and standardizing processes across Health Centers, ensuring compliance and sustainable outcomes while fostering collaboration and...
Today
Director, Global Program Manager - Oncology
$150K - $180K *
Lead the charge in driving cross-functional team effectiveness by translating complex strategies into actionable plans, managing risks, and optimizing performance to ensure alignment with enterprise o...
2 days ago
Clinical Operations Manager - OPA MSO
$95K - $120K *
Elevate clinical quality and safety by supporting regional operations, ensuring compliance, and driving performance improvement initiatives across multiple facilities. Collaborate with leadership to e...
2 weeks ago
Executive Director/Vice President, Clinical Development
$297K - $370K *
Champion the execution of global clinical programs, leading cross-functional teams in advancing innovative neuropsychiatric therapies. Leverage your expertise to drive strategy, oversee trial design...
Reposted 2 weeks ago
Director, Marketing - Health Plans & Health Systems
$150K - $206K *
Shape the future of health marketing by leading a dynamic team to drive member acquisition and provider engagement. Oversee comprehensive marketing strategies and align with cross-functional teams to...
4 weeks ago
$105K - $115K *
Make your mark at a leading residential treatment center by providing strategic leadership and clinical excellence. Guide dedicated teams to support adolescents facing behavioral health challenges, fo...
3 days ago
$187K - $255K *
Develop global regulatory strategies to ensure compliance and expedite drug approvals. Lead regulatory submissions, define processes, and guide cross-functional teams throughout the product lifecycle...
1 month ago
$80K - $95K *
Elevate clinical services as you supervise staff, enhance programming, and ensure documentation excellence. Collaborate across teams to optimize client care while maintaining oversight of residential...
4 weeks ago
$125K - $170K *
Champion operational excellence by leading multi-site healthcare practice management teams. Drive performance, efficiency, and financial stability while enhancing patient access and care quality throu...
4 weeks ago
$115K - $145K *
Lead clinical research projects, ensuring compliance with regulations and timelines. Collaborate with teams and sponsors, manage study functions, and drive effective communication to achieve trial mil...
2 weeks ago
Director, Pharmacovigilance Operations
$150K - $180K *
Pioneer operational excellence in pharmacovigilance by overseeing compliance, vendor management, and inspection readiness. Collaborate cross-functionally to ensure adherence to regulatory standards an...
1 week ago
$100K - $120K *
Transform patient care by leading clinic operations, ensuring quality and compliance, and fostering community partnerships. Drive initiatives to enhance patient experience and clinic efficiency while...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.