Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$100K - $120K *

Champion the adoption of MRD testing services by engaging clinicians and stakeholders, driving strategic business development, and maximizing client relationships within major cancer centers and healt...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $155K *

Transform healthcare by driving the adoption of MRD testing services. Collaborate with clinicians and key stakeholders to expand business opportunities and enhance patient outcomes in oncology diagnos...

California, USRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $145K *

Shape the future of IT security by designing and implementing IAM solutions, mitigating risks, and collaborating across teams to enhance security practices in a dynamic environment...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$102K - $134K *

Join a team that's redefining project estimating by leading the preparation of competitive bids and cost analyses for electrical construction projects. Collaborate with estimators and suppliers to ens...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$67K - $99K *

Contribute to footwear excellence by enhancing fit, quality, and durability. Collaborate with cross-functional teams to implement testing protocols and troubleshoot product issues, ensuring world-clas...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $100K *

Support a diverse team in delivering exceptional field service for high-tech vacuum products. Engage with customers, troubleshoot systems, and ensure operational excellence while traveling for install...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $150K *

Unlock exceptional workplace experiences by overseeing daily operations, enhancing service quality, and fostering collaboration across teams. Drive initiatives that elevate employee and client satisfa...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $150K *

Drive exceptional workplace experiences by overseeing daily operations, enhancing service quality, and fostering collaboration across teams to ensure a seamless environment for employees, clients, and...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$128K - $225K *

Unlock potential by leading cloud engineering strategy and product development. Oversee a high-performing team to deliver secure, scalable cloud solutions across multiple providers, ensuring alignment...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$71K - $118K *

Advance your career by analyzing and responding to cyber incidents in a dynamic 24x7 Security Operations Center, supporting U.S. State, Local, Tribal, and Territorial governments with critical securit...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$131K - $209K *

Engage with teams to deliver comprehensive AI enablement programs, designing tailored learning paths and fostering a culture of proficiency across all departments. Collaborate closely with HR to integ...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$75K - $88K *

Deliver comprehensive reporting and analytics support, collaborating with Practice Management and Business Analytics teams to enhance data-driven decision-making and maintain key performance metrics...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$159K - $207K *

Champion compliance excellence by overseeing healthcare regulations, ensuring ethical practices, and collaborating cross-functionally to uphold transparency and integrity in all operations...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive innovation by leading the development of machine learning models that enhance credit risk scoring, fraud detection, and customer segmentation in the banking sector, while mentoring junior data s...

Today

  •   8 - 10 years exp.  •   Business Services

$125K - $150K *

Elevate HR leadership by driving people strategies that enhance organizational effectiveness and employee engagement across multiple locations in the North America Industrial & Construction sector, pa...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Transportation

$107K *

Take ownership of secure transportation operations, ensuring safety and compliance while escorting individuals. Manage vehicle inspections and maintain legal standards, contributing to a reliable and...

Today

  •   Less than 5 years exp.  •   Staffing

$94K *

Drive secure transportation operations, ensuring safety and compliance while escorting individuals. Oversee vehicle inspections and maintain legal standards, providing exceptional service in high-stak...

Today

  •   Less than 5 years exp.  •   Staffing

$132K *

Join a dynamic team as you ensure the safe transportation and escorting of individuals, maintaining high security standards while operating vehicles safely and legally. This role offers opportunities...

Today

  •   Less than 5 years exp.  •   Staffing

$107K *

Join a team that's dedicated to secure transportation and escort services. Ensure safety and compliance while operating vehicles and managing individuals during transit. Your expertise will contribute...

Today

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Lead the charge in enhancing equipment performance and managing capital projects across multiple manufacturing sites, ensuring operational excellence and financial accountability through strategic pro...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$95K - $115K *

Join a team that's committed to delivering exceptional critical care. You will provide comprehensive patient support in various ICU settings, utilizing evidence-based practices to ensure optimal outco...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a dynamic healthcare team to provide exceptional perioperative patient care. Utilize your nursing expertise to collaborate with multidisciplinary teams, ensuring safe and effective treatment whil...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead multidisciplinary automation projects, transforming manual processes into fully automated systems. Collaborate with cross-functional teams to design, qualify, and sustain innovative solutions fro...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Champion the future of automation engineering by leading multidisciplinary design and integration efforts, transforming manual processes into fully automated solutions across various domains and colla...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Lead the charge in building a unified technical organization that enhances customer experience through application support and field service, driving project conversions and fostering a culture of con...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.