Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$140K - $202K *

Lead the charge in designing and integrating avionics systems for cutting-edge spacecraft. Collaborate with engineering teams to ensure mission success through innovative solutions and rigorous testin...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$145K - $165K *

Lead the charge in quality operations across aerospace manufacturing, ensuring product integrity and compliance while driving continuous improvement and fostering a culture of accountability and excel...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$138K - $180K *

Shape the future of medical device development by driving project execution, collaboration, and innovation within a dynamic Research & Development team focused on enhancing healthcare outcomes and pat...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$99K - $129K *

Elevate product quality and compliance by providing expert quality engineering support in high-volume medical device manufacturing. Collaborate with cross-functional teams to drive continuous improvem...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$105K - $108K *

Elevate customer care by managing key accounts, driving performance, and fostering long-term relationships. Collaborate with cross-functional teams to deliver exceptional value, resolve issues, and im...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$198K - $258K *

Lead the charge in defining and governing architectural strategies for a secure and scalable software ecosystem across device and digital platforms, influencing cross-functional teams and senior stake...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Healthcare

$105K *

Transform key account relationships while ensuring customer satisfaction and performance. Collaborate across teams to drive business outcomes and support high-volume accounts, advocating for solutions...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$127K - $165K *

Unlock potential by leading regulatory strategies for innovative medical devices. Collaborate with teams to ensure compliance, execute FDA submissions, manage project timelines, and establish processe...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$78K - $139K *

Join a team that's dedicated to driving growth and enhancing customer relationships. As a leader, you'll coach and develop a high-performing branch team, ensuring operational excellence while managing...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $149K *

Champion efficient inventory and cost accounting processes, leading cross-functional collaborations. Drive accuracy in financial performance metrics while overseeing accounting operations in a dynamic...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$200K - $250K *

Lead the vision and execution of innovative AI-driven media buying platforms, driving cross-functional collaboration, growth, and product strategy to enhance customer experiences in the evolving AdTec...

Reposted today

  •   8 - 10 years exp.  •   Media

$70K - $98K *

Join a team that's dedicated to providing compassionate patient care. As a Licensed Vocational Nurse, you will support medical staff and ensure patient safety, comfort, and confidentiality while perfo...

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Champion the design and implementation of Data Vault 2.0 standards while leading the development of a canonical data model for non-financial data domains. Engage with cross-functional teams to ensure...

Reposted today

  •   8 - 10 years exp.  •   Legal & Accounting

$146K - $306K *

Drive operational excellence by leading materials management and supply chain strategies. Ensure material readiness and continuity across manufacturing programs while fostering cross-functional collab...

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $250K *

Join us as you lead the vision and execution for AI-driven media buying platforms, shaping strategies for growth and automation while developing a high-performing product team in a fast-evolving AdTec...

Reposted today

  •   8 - 10 years exp.  •   Media

$200K - $250K *

Unlock potential by leading data architecture for a cutting-edge digital law firm. Drive the establishment of data governance standards and design methodologies, enhancing non-financial data domains w...

Reposted today

  •   8 - 10 years exp.  •   Legal & Accounting

$83K - $93K *

Join a team that's dedicated to servicing and repairing CNC machine tools. Perform complex diagnostics and repairs, ensuring operational excellence through customer interaction, advanced troubleshooti...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $283K *

Champion regulatory excellence by leading CMC strategies for small molecule programs, ensuring compliance and driving successful submissions from early development through commercialization in a dynam...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Shape the future of security in a high-growth SaaS environment by leading a talented team to enhance our AWS security posture, drive strategy, and ensure compliance with industry standards...

Reposted today

  •   5 - 7 years exp.  •   Media

$120K - $140K *

Unlock your potential by building and deploying cutting-edge machine learning and deep learning solutions. Collaborate across teams to drive business insights through end-to-end data science pipelines...

Today

  •   Less than 5 years exp.  •   Information Technology

$200K - $250K *

Join a team dedicated to advancing data architecture through innovative Data Vault 2.0 methodologies. Lead initiatives to establish a robust canonical data model, ensuring data accuracy and integrity...

Reposted today

  •   8 - 10 years exp.  •   Legal & Accounting

$190K - $225K *

Drive innovation as you lead the development of an AI-driven self-serve TV platform, transforming TV ad tech through automation and optimization to empower marketers with data insights for impactful c...

Reposted today

  •   Less than 5 years exp.  •   Media

$250K - $325K *

Join a cutting-edge team to optimize AI inference for gaming on-device, translating innovative models into efficient, real-time experiences across diverse platforms, while leading engineering practice...

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$80K - $85K *

Lead the future of multi-unit operations by overseeing 5-10 parks, driving revenue growth, and fostering team development. Collaborate with executives to implement innovative strategies that enhance p...

Today

  •   5 - 7 years exp.  •   Hospitality & Recreation

$244K - $317K *

Partner with us to redefine quality assurance in Gaming AI. Lead the charge in building innovative AI-assisted quality systems that ensure fast, reliable, and exciting game production through advanced...

Reposted today

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.