Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Average Salary: $142,597
eCommerce Content Manager - PRAVANA & Zotos Professional
$100K - $120K *
Advance your career by leading digital content strategies that enhance brand visibility and drive eCommerce success. Collaborate with cross-functional teams to create engaging content that resonates w...
Today
$95K - $115K *
Join a vibrant culinary team as you drive menu innovation, lead with creativity, and oversee high-volume operations. Inspire collaboration and deliver exceptional dining experiences across multiple ou...
Reposted today
Executive Director, Clinical Operations
$285K - $310K *
Lead the strategic execution of global clinical trials, ensuring adherence to timelines, budgets, and quality standards while fostering collaboration across teams and mentoring Clinical Operations per...
Today
Staff Software Engineer, Partner Integrations
$229K - $260K *
Transform the integration landscape by architecting robust connections between NodeZero and key security platforms, ensuring reliability and observability while mentoring engineers and driving technic...
Today
Finance Transformation Manager
$130K - $160K *
Innovate finance transformation by automating workflows and integrating data systems. Collaborate with cross-functional teams to enhance reporting and streamline operations, ensuring a single source o...
Today
Design Expert, Sales - Interior Define
$85K - $100K *
Elevate your career by delivering exceptional design experiences and driving sales growth. Engage clients through personalized consultations, master product knowledge, and create stunning mood boards...
Today
$95K - $115K *
Engineer customer reliability by providing expert technical support for IoT solutions. Collaborate with teams to resolve issues, enhance documentation, and gather feedback, ensuring a seamless custome...
Today
Regional Manager - Northern California (Bay Area)
$110K - $130K *
Join a team that's revitalizing relationships and driving growth in Northern California. Lead and mentor a diverse sales team while collaborating with funeral home owners to unlock potential and achie...
Today
Commercial Banking Regional Manager
$195K - $364K *
Pioneer new business growth and ensure top-level performance through strategic regional management of commercial banking teams, relationships, and profitability initiatives for long-term success...
Reposted today
Advance Practice Provider Manager
$162K - $221K *
Unlock potential by leading advanced practice providers in pediatric care. Oversee operational management, drive quality initiatives, and enhance care delivery across cardiology and CT surgery, ensuri...
Today
Senior Agentic AI Engineer/Developer
$87K - $161K *
Launch your career by designing and implementing AI-driven security solutions that enhance automation and reduce repetitive tasks. Collaborate across teams to build robust, secure applications and str...
Today
$114K - $165K *
Transform patient care in a dynamic PICU environment, collaborating with a multidisciplinary team to deliver exceptional support for critically ill children and young adults. Your expertise will shape...
Today
Senior Manager, Corporate Accounts | Remote US
$122K - $212K *
Lead national account strategies for corporate customers in MedTech, fostering executive relationships and driving growth through strategic partnerships and cross-functional collaboration to enhance p...
Today
Sr. Distinguished Scientist - PSTS Neuroscience Disease Area Lead
$173K - $299K *
Join a leading neuroscience team as a scientific expert driving strategic planning and development. Collaborate across functions to ensure regulatory compliance and scientific excellence from discover...
Reposted today
Supervisor 1 Manufacturing Production
$91K - $147K *
Take ownership of production operations by supervising teams, driving process improvements, and fostering collaboration. Utilize Lean and Six Sigma methodologies to enhance efficiency and ensure opera...
Today
Detailed Scheduler/Pre-Identified Candidate
$75K - $106K *
Inspire operational excellence by translating production plans into detailed schedules. Collaborate with cross-functional teams to optimize resources, enhance efficiency, and ensure timely delivery of...
Today
$75K - $120K *
Drive continuous improvement in manufacturing processes and systems. Collaborate cross-functionally to enhance efficiency, safety, and quality. Execute engineering projects while developing problem-so...
Today
$109K - $174K *
Lead and execute clinical trials in compliance with regulations and timelines, handling everything from study design to data review. Collaborate with teams to ensure successful project delivery and ad...
Reposted today
Medical Science Liaison - Hematology (West Los Angeles/Central CA
$117K - $201K *
Help us elevate patient care as a Medical Science Liaison, driving scientific exchange and relationship-building with key healthcare leaders in Hematology. You will be integral in strategizing medical...
Reposted today
Medical Science Liaison - Hematology (West Los Angeles/Central CA
$117K - $201K *
Join a dedicated team to shape innovative medical solutions. As a key expert, engage healthcare professionals, foster scientific collaboration, and drive impactful insights to enhance patient care and...
Reposted today
Medical Science Liaison - Hematology (West Los Angeles/Central CA
$117K - $201K *
Unlock potential by driving scientific engagement and collaboration with key health care professionals in a dynamic medical landscape, enhancing relationships, generating insights, and ensuring compli...
Reposted today
Medical Science Liaison - Hematology (West Los Angeles/Central CA
$117K - $201K *
Unlock potential by joining a dynamic team as a Medical Science Liaison, where you'll drive scientific engagement, cultivate key relationships, and provide valuable insights to healthcare professional...
Reposted today
Medical Science Liaison - Hematology (West Los Angeles/Central CA
$117K - $201K *
Drive scientific exchange and develop relationships with KOLs in hematology, ensuring high-quality insights align with medical strategy. Pioneer innovative approaches, staying informed on treatment tr...
Reposted today
$94K - $164K *
Champion user experience design across digital products, driving insights into actionable solutions. Collaborate with cross-functional teams to enhance customer journeys and ensure alignment with Huma...
Today
$94K - $164K *
Champion cost reporting processes by ensuring data accuracy, preparing detailed reports, and analyzing financial information. Collaborate across departments to enhance reporting systems and support st...
Today
What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.