Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing companies. Whether you’re looking for a leadership position or your next specialized role, find opportunities that match your experience and career goals.

Career opportunities across California

California’s broad economy offers roles in fields such as technology, entertainment, healthcare, finance, biotechnology, clean energy, and professional services. Opportunities can be found in major employment centers including Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and other communities throughout the state. Job availability and compensation vary by employer, location, role, and qualifications.

Find roles that fit your experience

Use job details to compare responsibilities, required skills, work arrangements, and compensation. Search for positions by title, industry, or location, and review each listing for its specific salary range and requirements. Tailor your resume to highlight relevant results, expertise, and leadership experience when applying.

Search California jobs on Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more. Explore California listings to identify opportunities aligned with your background, preferred location, and next career move. Listings change frequently, so check back for newly available roles.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,595

Sort By: Relevance

$135K - $160K *

Unlock potential by leading advancements in robotics and Physical AI. Drive research adoption, technology development, and industry engagement to create intelligent robotic systems that interact seaml...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$75K - $115K *

Elevate your career by leading a dynamic team of Systems Engineers, driving technical excellence and enhancing service delivery in a fast-paced corporate IT environment focused on endpoint management...

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$165K - $175K *

Lead global clinical trials, managing cross-functional teams to ensure project success across multiple therapeutic areas while driving operational excellence and best practices in clinical project man...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Staffing

$115K - $127K *

Join a team that's dedicated to advancing oncology research by monitoring clinical trials, ensuring compliance, and supporting investigative sites throughout the trial lifecycle. Your expertise will d...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Staffing

$165K - $185K *

Champion integrated facilities management by overseeing operations, enhancing client relations, and ensuring operational excellence while navigating rapid change and ambiguity across multiple sites...

Reposted yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$70K - $110K *

Champion the implementation and support of Windows Server environments, ensuring optimal performance and security across diverse customer infrastructures while collaborating with technical teams and s...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$135K - $232K *

Lead strategic initiatives to enhance client retention and growth for large accounts. Collaborate with executives, develop multi-year plans, and manage renewals while ensuring seamless service deliver...

Reposted yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$135K - $232K *

Advance your career by developing strategic retention plans for large, complex clients. Collaborate with executives, manage renewals, and drive growth in specialty business areas while leading initiat...

Reposted yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$135K - $232K *

Unlock growth by developing strategic retention plans for complex national accounts. Collaborate with executives to enhance client relationships and drive specialty business growth while managing rene...

Reposted yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$127K - $159K *

Drive statistical leadership in oncology clinical development, guiding study design, analysis, and regulatory submissions. Collaborate with cross-functional teams to ensure high-quality deliverables a...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive innovative strategies in generative engine optimization, leading client accounts and teams to enhance visibility and authority in AI-driven search landscapes while ensuring measurable outcomes a...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $190K *

Transform your career by leading a dynamic team to enhance Siri Settings and compliance across Apple platforms, ensuring seamless user experiences while driving technical excellence and collaboration...

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$138K - $190K *

Lead the charge in flight control law design and embedded software development for prototype vehicles. Collaborate across teams to support rapid prototyping, ensuring technical feasibility and adheren...

San Jose, CARemote

Reposted yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $145K *

Transform your career by designing and validating OLED display prototypes, collaborating with engineers and vendors in a cross-functional team to innovate in optoelectronics. Join us to shape the futu...

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Engage in full-stack development to enhance Specialty Care experiences. Collaborate with cross-functional teams to drive growth and retention through innovative solutions and rapid experimentation, wh...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Engage in shaping the next generation of Siri's interaction ecosystem, developing robust software solutions across diverse platforms and collaborating with engineers from multiple disciplines to enhan...

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$165K - $215K *

Accelerate customer success by fostering AI adoption, driving use cases, and ensuring SMB and Mid-Market clients achieve meaningful outcomes through tailored solutions and collaborative workshops with...

San Francisco, CARemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$320K - $400K *

Take ownership of building a comprehensive kidney and liver transplant program, fostering collaboration across multidisciplinary teams to ensure exceptional clinical outcomes and patient-centered care...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$112K - $170K *

Champion the sales of Identity Security Solutions by leading a collaborative team, engaging customers, and exceeding revenue goals through strategic planning and exceptional service delivery...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$108K - $130K *

Lead the charge in optimizing data processes and enhancing operational efficiency. Collaborate with stakeholders to translate business needs into actionable insights while ensuring compliance and secu...

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$228K - $309K *

Lead the charge in advancing frontier Generative AI by designing and evaluating innovative reinforcement learning environments, setting technical direction, and mentoring junior scientists to enhance...

Yesterday

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$163K - $244K *

Join a team that's dedicated to enhancing training programs in electric utility operations. Collaborate with experts to develop curriculum, deliver hands-on training, and ensure compliance with safety...

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $93K *

Grow your career with a dynamic Finance team as a Staff Accountant, supporting financial operations for R&D programs and USG contracts. Collaborate across departments to ensure accurate financial reco...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Advance healthcare solutions by developing scalable ML systems, collaborating with cross-functional teams, and driving innovative AI methodologies to enhance patient outcomes and optimize operational...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$72K - $90K *

Shape the future of business travel by managing bid responses and collaborating with teams to ensure high-quality proposals that meet client needs and company standards. Engage with subject matter exp...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, biotechnology, entertainment, clean energy, and other industries. Available positions depend on current employer hiring needs.

  • Which California cities have professional job opportunities?question toggle

    Opportunities may be listed in Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and other cities and regions across the state. Search by location to see current openings.

  • Do all jobs listed in California pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Review each listing for its specific compensation details, since salary ranges and terms can vary.

  • How can I find a California job that matches my experience?question toggle

    Search by job title, location, or industry, then compare each listing’s responsibilities and qualifications with your background. Highlight relevant skills and measurable accomplishments in your application.

  • Are remote or hybrid California jobs available?question toggle

    Some employers may offer remote or hybrid arrangements, while others require on-site work. Check each job listing for its work location and arrangement.