Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$96K - $151K *

Join a team that's transforming healthcare by developing analytic products from clinical data. Collaborate in an agile environment to deliver insights that enhance efficacy and drive innovation in the...

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  •   Less than 5 years exp.  •   Healthcare

$145K - $175K *

Join us to define and drive the enterprise cloud database strategy, leading architecture and modernization efforts to create scalable, reliable solutions for healthcare applications serving millions o...

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  •   8 - 10 years exp.  •   Healthcare

$108K - $130K *

Lead the development of innovative bioassays and analytical methods for biologics, enhancing understanding of kinetics and mechanisms of action. Collaborate cross-functionally while maintaining compli...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a team that's redefining mortgage origination through a powerful API. As a Lead PM, you'll shape the API strategy, enhance developer experience, and ensure compliance while driving innovation in...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$118K - $147K *

Engage in technical project management to advance global industry standards. Collaborate with cross-functional teams, lead initiatives, and drive consensus in the semiconductor sector, enhancing produ...

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  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $130K *

Manage day-to-day accounting operations, ensuring accurate financial records and timely reporting. Collaborate with cross-functional teams to enhance processes and support financial close activities i...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $170K *

Optimize revenue operations by partnering with leadership to enhance GTM strategies, manage HubSpot systems, and drive data quality. Lead analytics and reporting while fostering cross-functional align...

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  •   8 - 10 years exp.  •   Finance & Insurance

$147K - $202K *

Drive innovation in semiconductor manufacturing by optimizing processes, analyzing data, and collaborating with cross-functional teams to enhance device performance and resolve engineering challenges...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Drive patient care excellence by collaborating with interdisciplinary teams to assess, plan, and implement effective care strategies. Mentor new nurses while ensuring optimal patient outcomes and read...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$75K - $100K *

Join a dynamic team in the beer, wine, and spirits industry, where you'll build and nurture customer relationships, drive sales, and achieve objectives in a fast-paced environment. Your passion for se...

Today

  •   Less than 5 years exp.  •   Transportation

$70K - $120K *

Lead the charge in developing a high-performing recruitment team, driving market growth and client relationships while mentoring consultants to achieve their full potential in a thriving Go-to-Market...

Today

  •   Less than 5 years exp.  •   Staffing

$114K - $184K *

Join us to lead cybersecurity initiatives for critical systems, ensuring secure DevSecOps practices. You'll implement RMF, manage vulnerabilities, and collaborate with Navy officials to maintain compl...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Shape the future of aerospace by leading system-level verification and validation for Flight Control Systems. Collaborate across teams to ensure compliance, performance, and safety in innovative aircr...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $184K *

Join our team to lead and manage complex electrical engineering projects. Collaborate with clients and design professionals to create innovative solutions in a fast-paced environment. Elevate your car...

Reposted today

  •   8 - 10 years exp.  •   Technical Services

$120K - $184K *

Join our team to lead complex electrical engineering projects, overseeing design processes and collaborating with clients. Utilize your expertise to ensure project success while mentoring junior staff...

Reposted today

  •   8 - 10 years exp.  •   Technical Services

$114K - $253K *

Unlock potential by managing complex projects within Spares Operations, driving cross-functional collaboration to optimize processes and deliver strategic solutions on time and within budget, while in...

Today

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$160K - $185K *

Advance creative strategies as an Associate Creative Director, focusing on impactful campaign concepts and copy that drive business results. Work with a high degree of autonomy and influence as you sh...

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Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $190K *

Lead the charge in building a dynamic litigation team in the Inland Empire. Bring your expertise to handle complex cases independently while mentoring junior attorneys and shaping the future of our gr...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$160K - $185K *

Elevate creative strategy by transforming insights into compelling campaigns. Drive messaging, concepts, and copy direction that enhance business outcomes while collaborating closely with designers an...

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Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $195K *

Shape the future of payroll and HRIS integrations by ensuring reliability and success. Collaborate with customers and partners to solve technical challenges and enhance the integration experience whil...

United StatesRemote

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  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Unlock potential by leading financial services engagements, transforming client needs into AI-driven products. Shape the future of finance with your expertise, driving adoption and building a dedicate...

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$237K - $296K *

Manage comprehensive primary care services for elderly participants, ensuring high-quality, patient-centered care across various settings. Collaborate with an interdisciplinary team to promote wellnes...

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Optimize patient care by delivering direct services under physician supervision. Engage in diagnostic tasks, maintain quality standards, and foster professional relationships to enhance healthcare del...

Today

  •   Less than 5 years exp.  •   Healthcare

$160K - $195K *

Unlock potential by owning the reliability of payroll and HRIS integrations. Collaborate with customers and partners to solve technical challenges, ensuring seamless experiences while driving operatio...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$72K - $105K *

Lead the charge in managing branch operations, ensuring compliance, enhancing customer satisfaction, and driving team performance. Develop strategies for growth while mentoring staff to achieve high s...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.