Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Account Director Jobs in Missouri

Sort By: Relevance

$150K - $180K *

Lead the charge in shaping pricing strategy for a key region, overseeing a talented team to drive profitable growth while navigating complex regulatory environments and leveraging data for strategic d...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$102K - $193K *

Elevate your career by leading a dynamic sales team, driving growth through strategic partnerships, and executing innovative healthcare solutions while achieving personal and team sales goals in a col...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$109K - $135K *

Drive national media strategy by collaborating with cross-functional teams to translate consumer insights into actionable media investments, ensuring alignment with business objectives and adapting to...

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$109K - $135K *

Transform media strategy by leading national initiatives that connect brands with consumers. Collaborate with cross-functional teams to leverage insights and drive innovative media investments across...

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$173K - $198K *

Lead the evolution of data architecture, driving real-time capabilities and AI integration. Collaborate with executives and teams to enhance data quality, governance, and scalability while mentoring a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $190K *

Elevate our field marketing strategy by leading regional initiatives that drive demand for our software. Collaborate with sales teams to create impactful events and programs, while building and managi...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $125K *

Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Reimagine the employee experience by leading global Total Rewards and People Operations. Shape compensation, benefits, and HR systems while driving data insights and operational excellence to enhance...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform data into actionable insights by mastering analytics across diverse domains. Collaborate with cross-functional teams to optimize reporting workflows and drive impactful solutions in a fast-p...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Shape the future of product development by leading cross-functional teams to deliver innovative solutions from concept to launch, ensuring alignment with business goals and quality standards...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$111K - $139K *

Build strategic supplier relationships to drive growth and profitability. Lead cross-functional initiatives, negotiate contracts, and mentor a high-performing team while ensuring supplier performance...

Missouri, USRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Drive your career forward by overseeing essential accounting activities, ensuring compliance with GAAP and government contracting regulations. Leverage your expertise in financial reporting, general l...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $190K *

Drive impactful multi-channel field marketing strategies that enhance demand generation, strengthen customer relationships, and optimize pipeline performance. Lead a high-performing team while collabo...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Empower your career by bridging technical solutions and customer needs in the drive-thru technology space. Collaborate with Sales and Product teams to design and deliver innovative solutions that enha...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Grow your career by driving strategic sales in a dynamic cybersecurity landscape, collaborating with leaders and partners to expand market presence and achieve impressive business growth. Engage with...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Elevate your career by managing diverse capital improvement projects, serving as a trusted advisor throughout the project lifecycle, and ensuring exceptional client service while meeting scope, budget...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $110K *

Join a team that's redefining creative operations! Lead resource management, optimize workflows, and foster collaboration across teams to deliver exceptional creative solutions for clients in a dynami...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$127K - $223K *

Lead the charge in optimizing user journeys for engagement and retention. Design multi-channel re-engagement strategies for high-value client interactions, focusing on maximizing long-term value throu...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Join a team that's dedicated to enhancing employee experiences globally. Lead HR partnerships, support managers through change, and drive engagement initiatives while managing complex employee relatio...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $225K *

Champion growth and profitability by leading a regional underwriting team. Drive strategic initiatives, manage agency relationships, and mentor staff to enhance operational effectiveness and ensure al...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $100K *

Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $225K *

Drive growth by identifying and closing enterprise accounts through strategic outreach and relationship building. Manage complex sales cycles and ensure seamless transitions for long-term customer suc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Pioneer sustainable growth by leading strategic initiatives, strengthening client relationships, and enhancing operational excellence in commercial construction. Drive performance and cultivate top ta...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K - $130K *

Champion the development of AI-driven products, leading strategic initiatives and execution. Drive product roadmaps, manage budgets, and ensure alignment with business goals while delivering impactful...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $135K *

Lead the charge in managing high-severity, complex insurance claims, focusing on EPL and Professional Liability. Serve as a subject matter expert, ensuring compliance and strategic resolution while ad...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.