Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Sr. Mid-Market Account Manager
$104K - $123K *
Elevate your career as a strategic advisor to mid-market clients, driving growth and revenue. Manage your own portfolio, build lasting partnerships, and uncover new business opportunities in this dyna...
Reposted 1 week ago
Senior Marketing Events Manager
$110K - $130K *
Join a team that's redefining event marketing by leading high-impact programs that enhance customer engagement and drive revenue. You'll strategize and execute user summits, trade shows, and field eve...
2 weeks ago
$120K - $145K *
Join a team that's redefining media pricing and transactions by creating and executing customer-focused product strategies, enhancing user engagement, and navigating a complex media landscape through...
Reposted 3 weeks ago
Director, Audience & Connections Strategy
$118K - $130K *
Champion cross-channel strategies by blending audience insights with connections planning. Collaborate with teams to create impactful consumer journeys and drive brand engagement through data-driven s...
1 week ago
Principal Software Architect (Graph Architect)
$150K - $180K *
Lead the architectural vision for scalable Identity Resolution platforms, driving innovation in enterprise applications and data processing. Collaborate with engineering teams to ensure robust, high-p...
3 weeks ago
AVP - Financial Planning & Analysis
$154K - $204K *
Champion strategic financial planning and analysis, driving enterprise-wide initiatives and insights. Lead a high-performing team, enhance reporting capabilities, and support executive decision-making...
3 weeks ago
Associate / Analyst, Strategic Initiatives
$90K - $120K *
Advance strategic initiatives by collaborating across teams to launch innovative data tools and insurance programs. Drive project management efforts and contribute to executive presentations that shap...
6 days ago
Executive Director, Translational Medicine & Pediatric Planning
$246K - $332K *
Drive pediatric development strategy by integrating clinical insights and regulatory commitments across multiple therapeutic areas, ensuring effective execution from candidate transition to post-marke...
2 weeks ago
Project Manager II, Global Project Leadership
$95K - $115K *
Drive the successful delivery of complex global clinical trials, overseeing cross-functional teams and ensuring compliance with GCP and regulatory standards while managing budgets and timelines to exc...
3 weeks ago
Senior Director, Global Field Operations
$175K - $210K *
Lead global field operations, driving strategy and execution across sales, technical services, and partner functions. Collaborate with senior leadership to optimize pipeline management, forecasting, a...
3 weeks ago
$80K - $95K *
Drive plant-level sales strategies and cultivate customer relationships to enhance beverage production. Collaborate with teams to identify opportunities and deliver solutions, ensuring consistent prod...
3 weeks ago
Senior Director, Direct to Consumer
$150K - $180K *
Shape the future of direct-to-consumer strategies by leading multi-channel growth initiatives, optimizing consumer experiences, and driving profitability across retail and digital platforms while coll...
2 weeks ago
Project Manager, Industry Specialty Services
$125K - $165K *
Manage technology implementations and strategic projects, coordinating across stakeholders to ensure successful delivery while adhering to budgets, schedules, and quality standards. Leverage project m...
Today
$110K - $130K *
Oversee the design and development of clinical databases while ensuring project timelines and quality standards are met. Collaborate across teams to provide technical support and mentor team members...
Reposted 2 weeks ago
Project Director - Documentation Integrity
$100K - $120K *
Shape the future of clinical documentation integrity by leading audits and compliance initiatives across facilities. Collaborate with healthcare teams to enhance operational efficiency and ensure adhe...
6 days ago
$122K - $183K *
Join a team that's driving strategic growth by partnering with leading OEMs. You'll influence product roadmaps, uncover market opportunities, and translate customer insights into scalable solutions fo...
4 weeks ago
Sales Director, Mid-Market & SMB (Gracenote Division)
$125K - $150K *
Accelerate growth by leading commercial strategy and sales for Mid-Market & SMB segments. Drive revenue, manage KPIs, and collaborate cross-functionally to enhance client satisfaction and market prese...
Today
Senior Account Manager, Life Sciences (Los Angeles)
$120K - $150K *
Drive customer satisfaction and sales in life sciences by leveraging your expertise to build relationships and execute strategic initiatives with key accounts in academia and industry...
2 weeks ago
$90K - $110K *
Lead the charge in managing contracts for utility-scale solar and infrastructure projects. Collaborate with cross-functional teams to ensure compliance, streamline documentation, and support project c...
3 weeks ago
Account Manager, Client Development & Renewals (Chicago / Midwest)
$123K - $135K *
Engage with existing customer accounts to drive renewal retention and expansion revenue. Collaborate with cross-functional teams to identify growth opportunities and ensure customer satisfaction while...
1 week ago
Senior Director, Web Strategy and Operations
$160K - $200K *
Shape the future of our web strategy by leading a cross-functional team to optimize user experience, drive demand generation, and enhance web performance. Your expertise will transform our website int...
1 week ago
Senior Director, Client Sales & Insights
$100K - $130K *
Drive commercial activation and revenue growth for a multi-million-dollar portfolio, leveraging strategic insights and AI to enhance client engagement and decision-making. Lead cross-functional teams...
4 days ago
$95K - $110K *
Shape innovative marketing strategies as a Senior Art Director, leading creative projects that align with client objectives. Collaborate with teams to deliver impactful visual content, driving busines...
Reposted 2 weeks ago
Senior Business Development Representative, LATAM & North America
$90K - $120K *
Engage in strategic pipeline development to drive revenue across LATAM and North America. Utilize consultative selling and AI tools to connect with technical decision-makers, ensuring high-quality out...
6 days ago
Director, Professional Services Group
$120K - $150K *
Join a team that's shaping the future of consulting in P&C insurance. Lead client engagements, ensure quality standards, and foster long-term relationships while driving business growth and mentoring...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.