Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$225K - $285K *

Transform enterprise client relationships by driving strategy, growth, and delivery quality. Lead a portfolio with full P&L accountability, ensuring client success and fostering thought leadership in...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$200K - $270K *

Shape the future of immunotherapy by leading access strategies for a groundbreaking T-cell therapy. Collaborate with cross-functional teams to ensure timely payer engagement and coverage decisions, ma...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $150K *

Build trust and deliver tailored security solutions to customers. Engage in dynamic sales, providing expert advice and follow-ups while cultivating new business opportunities in a collaborative enviro...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$150K - $250K *

Champion innovation by optimizing workflows and AI-driven operations to enhance efficiency across diverse business functions. Collaborate closely with teams to build scalable systems that drive real i...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$125K - $150K *

Drive investment strategy and governance by leading portfolio management, manager research, and market insights. Collaborate with cross-functional teams to enhance investment solutions and ensure disc...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $215K *

Collaborate with senior leaders to design and implement global HR strategies, driving organizational performance and employee engagement while leading a team of HR professionals in a dynamic environme...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $216K *

Engineer impactful data center projects by leading large teams, fostering customer relationships, and leveraging advanced technologies. Drive continuous improvement and ensure successful delivery of h...

3 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$150K - $180K *

Lead the charge in shaping pricing strategy for a key region, overseeing a talented team to drive profitable growth while navigating complex regulatory environments and leveraging data for strategic d...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$102K - $193K *

Elevate your career by leading a dynamic sales team, driving growth through strategic partnerships, and executing innovative healthcare solutions while achieving personal and team sales goals in a col...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$173K - $198K *

Lead the evolution of data architecture, driving real-time capabilities and AI integration. Collaborate with executives and teams to enhance data quality, governance, and scalability while mentoring a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$150K - $190K *

Elevate our field marketing strategy by leading regional initiatives that drive demand for our software. Collaborate with sales teams to create impactful events and programs, while building and managi...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$175K - $195K *

Shape strategic partnerships and lead business development efforts, driving growth and execution across opportunities while fostering relationships with key industry stakeholders. Manage BD operations...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$108K - $130K *

Drive operational excellence by coordinating plant functions to ensure top-quality products and services. Collaborate with teams to meet objectives, manage budgets, and uphold compliance standards whi...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$143K - $160K *

Unlock potential by providing global legal support for commercial transactions, managing contracts, and ensuring compliance. Collaborate with teams to drive product development and protect intellectua...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Pioneer client relationships by managing elite advisor plans, ensuring exceptional service and retention. Collaborate with sales and operations to deliver consultative support, troubleshoot issues, an...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Champion client relationships by providing consultative support and strategic solutions. Drive retention and satisfaction for elite advisor plan clients through proactive engagement and collaboration...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$300K - $500K *

Unlock potential by leading strategic initiatives in clean fuels finance, building relationships with key stakeholders, and advising on capital structures to drive growth and innovation in the renewab...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $125K *

Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Transform data into actionable insights by mastering analytics across diverse domains. Collaborate with cross-functional teams to optimize reporting workflows and drive impactful solutions in a fast-p...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Shape the future of product development by leading cross-functional teams to deliver innovative solutions from concept to launch, ensuring alignment with business goals and quality standards...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $143K *

Champion the evolution of Strategic Finance by building robust models and AI-driven workflows. Collaborate with leadership to shape strategy and deliver insights that drive impactful business decision...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Drive your career forward by overseeing essential accounting activities, ensuring compliance with GAAP and government contracting regulations. Leverage your expertise in financial reporting, general l...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $190K *

Drive impactful multi-channel field marketing strategies that enhance demand generation, strengthen customer relationships, and optimize pipeline performance. Lead a high-performing team while collabo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Grow your career by driving strategic sales in a dynamic cybersecurity landscape, collaborating with leaders and partners to expand market presence and achieve impressive business growth. Engage with...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$177K - $221K *

Join us to lead global product launches, driving excellence through strategic planning, cross-functional collaboration, and continuous improvement. You'll manage launch readiness and establish standar...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.