Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$185K - $215K *

Drive the development of Contract Financials, collaborating with cross-functional teams to enhance value-based care products. Own the roadmap, prioritize client needs, and ensure successful feature de...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $140K *

Innovate financial strategies by partnering with R&D leaders to optimize costs, enhance reporting frameworks, and drive accurate forecasting in a dynamic environment. Your analytical skills will shape...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Explore a pivotal role overseeing financial management, budgeting, and compliance. Collaborate with leadership to provide insights that drive operational decisions and ensure organizational sustainabi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Media

$135K - $150K *

Unlock potential by overseeing project operations and client relationships, driving growth through strategic partnerships and best practices. Lead teams to achieve business goals while ensuring high s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $160K *

Lead the charge in executing population health strategies, ensuring high-quality consulting delivery and team performance across regions. Collaborate with leadership to drive impactful solutions and f...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Inspire growth by driving enterprise partnerships in healthcare. Leverage your sales expertise to lead complex cycles, build relationships with C-suite stakeholders, and shape strategic initiatives in...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $140K *

Unlock potential by translating complex scientific data into clear, impactful communication. Collaborate across teams to shape strategy and elevate medical communications that enhance patient outcomes...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $265K *

Champion governance excellence by leading policy frameworks, enhancing Board operations, and driving AI-enabled improvements. Engage with investors and committees to elevate governance practices at a...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$80K - $92K *

Unlock insights as you support senior analysts in corporate bond and bank loan research. Collaborate on financial models, enhance credit processes, and develop your analytical skills in a dynamic inve...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$200K - $275K *

Unlock your potential by leading a dynamic sales team focused on early cancer screening. Drive strategic initiatives, develop talent, and collaborate across departments to enhance patient care and ach...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Inspire patient recruitment strategies by leading a dynamic team, collaborating with senior management, and leveraging innovative tools to enhance enrollment across clinical trials while ensuring dive...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$165K - $210K *

Transform retail sales strategies and lead a dynamic team to achieve revenue goals. Drive account management, develop talent, and collaborate with cross-functional teams to enhance product offerings a...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$145K - $175K *

Unlock potential by leading the architecture and engineering of enterprise infrastructure. Drive integration and rationalization post-acquisition while ensuring security and compliance. Collaborate wi...

4 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$145K - $175K *

Unlock the potential of our IT infrastructure by leading architecture strategy, integrating diverse environments post-acquisition, and ensuring robust security and compliance. Drive innovation while m...

4 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Transform the future of enterprise infrastructure by leading architecture strategy, integrating diverse environments post-acquisition, and ensuring robust security and compliance across cloud, network...

4 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$148K - $201K *

Drive category strategy and supplier relationships to enhance Market Access, Pricing, and Health Economics. Collaborate with cross-functional teams to optimize procurement processes and improve operat...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$185K - $344K *

Champion the evolution of field intelligence capabilities, driving strategic governance and analytics integration to enhance decision-making and execution support across the organization, ensuring ali...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Transform client relationships by leading customer success strategies, driving utilization, and maximizing retention across enterprise health systems. Oversee a high-performing team to ensure client s...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $375K *

Lead the charge in transforming life sciences commercial strategies, driving growth through innovative solutions and strategic partnerships. Shape high-impact engagements while fostering talent and de...

3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$192K - $288K *

Lead the charge in EDC Programming, overseeing global operations and ensuring high-quality clinical data management. Drive strategic initiatives, manage vendor relationships, and enhance data standard...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$274K - $371K *

Elevate patient care through innovative clinical strategies in obesity and cardiometabolic development. Collaborate across teams to design and implement late-phase studies, ensuring alignment with glo...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Grow your career with us as you drive enterprise sales growth in healthcare. Engage with health systems and pharmacies, managing key accounts while identifying new opportunities in digital health solu...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$84K - $115K *

Lead the charge in driving customer success for high-value accounts, ensuring seamless implementation, fostering strategic relationships, and mitigating churn risk while identifying growth opportuniti...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$71K - $125K *

Transform client relationships by supporting sales and credit functions, managing lending processes under $10M, and ensuring data integrity. Collaborate with teams to create impactful pitch materials...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.