Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$150K - $180K *

Take ownership of operational assessments to enhance effectiveness, identify risks, and drive performance improvements across functions. Collaborate with leaders to align practices with strategic goal...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$145K - $175K *

Join a team that's redefining AI-driven solutions by leading product development for an innovative tech concierge. Drive the evolution of agent capabilities, ensuring quality and reliability while col...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Optimize engagement and monetization strategies for an AI-driven product, transforming customer interactions into measurable growth. Lead cross-functional teams to innovate and implement effective use...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Lead the design and implementation of B2B revenue accounting processes, ensuring efficient contract-to-cash operations while collaborating with cross-functional teams to drive growth and reduce manual...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$78K - $126K *

Unlock potential by guiding healthcare organizations through complex Medicare and Medicaid reimbursement processes. Leverage your expertise to enhance regulatory reporting and drive financial performa...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$92K - $138K *

Empower your career by leading accounts receivable operations, optimizing cash flow, and enhancing team performance. Drive strategic initiatives, ensure compliance, and collaborate cross-functionally...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$92K - $138K *

Lead the strategic management of accounts receivable functions, optimizing cash flow and ensuring compliance. Collaborate with teams to enhance efficiency, resolve escalations, and drive performance a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $120K *

Join a mission-driven team as an Account Executive, where you'll engage with K-12 district leaders, build partnerships, and drive sales to improve outcomes for English learners across a diverse territ...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$94K - $151K *

Join a team that's shaping the future of insurance products by leading strategic initiatives, ensuring compliance, and driving market analysis. Collaborate with product managers to define vision and e...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$138K - $175K *

The Tax Director for the Real Estate Division will lead a team of tax professionals, focusing on Partnership and Corporate returns within the Community and Economic Development niche. This client-faci...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Transform the SAP sales landscape by leveraging your extensive network and expertise to drive new business acquisition in the manufacturing sector. Own the full sales cycle, from lead generation to cl...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $135K *

Advance your career by leading product strategy for workforce solutions. Collaborate with cross-functional teams to drive innovation, ensuring products meet market needs and deliver value to diverse s...

Iowa City, IARemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$240K - $270K *

Champion web-driven growth by managing comprehensive strategies to enhance GMV. Collaborate across teams to optimize funnel performance, drive conversion, and build capabilities in paid search, SEO, a...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$97K - $138K *

Unlock new opportunities by building strategic relationships and driving cloud security solutions. Collaborate with internal teams and engage with c-suite stakeholders to align Zscaler's offerings wit...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $125K *

Transform client relations through innovative sales strategies while achieving consistent targets in a dynamic market. Drive growth by effectively managing existing partnerships and exploring new oppo...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$500K+*

Lead the charge in building robust data systems that enhance personalization and optimize product experiences. Drive strategic direction for large-scale data pipelines while developing a high-performi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Hospitality & Recreation

$105K - $130K *

Unlock potential by driving sales growth in a defined territory through strategic relationship management and promotion of genetic diagnostic testing services to healthcare professionals and instituti...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Lead the charge in driving growth and innovation for life sciences learning solutions. You'll develop and execute business strategies, enhance client engagement, and modernize product offerings within...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $110K *

Empower corporate veterinary groups by driving software adoption and growth. Collaborate with cross-functional teams to develop strategic partnerships, influence decisions, and enhance customer satisf...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $220K *

Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join us in driving growth by acquiring new customers and expanding existing relationships. This field-oriented role requires a motivated hunter skilled in building pipelines and fostering executive co...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$115K - $240K *

Reimagine operational excellence as you lead infrastructure and production teams, ensuring reliability and innovation in technology delivery. Drive process improvements and foster collaboration to mee...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$175K - $210K *

Lead the execution of energy infrastructure investments, managing complex programs from development to delivery. Drive governance, cross-functional coordination, and external partnerships to ensure ti...

RemoteRemote

4 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$80K - $120K *

Unlock potential by driving impactful sales in the K-12 education sector. Engage with district leaders, manage complex sales cycles, and foster partnerships to enhance outcomes for English learners wh...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$200K - $250K *

Join us in shaping technical strategies and growth initiatives for federal opportunities. Collaborate across teams to develop compelling solutions that drive success in complex pursuits, ensuring alig...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.