Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$125K - $150K *

Accelerate growth by leveraging your sales expertise to drive strategic deals for Unified Commerce solutions. Collaborate cross-functionally to enhance product knowledge and execute go-to-market strat...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Accelerate sales growth by leading strategies and initiatives across the ANZ market. Collaborate with a multidisciplinary team to drive customer engagement, develop market strategies, and achieve reve...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Lead sales initiatives across multiple states, driving growth by building relationships with advisors and leveraging product expertise to exceed territory goals and enhance brand visibility...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Develop strategic leadership for a team managing complex client portfolios, driving retention, growth, and client experience objectives while fostering strong relationships with stakeholders and ensur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $235K *

Drive impactful product development for an innovative AI platform by collaborating with cross-functional teams, defining scalable capabilities, and ensuring compliance while delivering measurable cust...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $90K *

Lead the charge in driving sales growth by engaging independent physician practices. Utilize your expertise in full-cycle sales to build relationships, conduct virtual demos, and collaborate with team...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Champion impactful programs by leading cross-functional teams, driving strategic alignment, and ensuring seamless execution. Leverage your expertise to manage complex initiatives that delight customer...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $140K *

Empower healthcare providers by promoting innovative colorectal cancer screening solutions, delivering exceptional support and education while strategically expanding product adoption across a designa...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead a dynamic account management team, driving strategic relationships with major health systems. Foster high-touch engagement, ensuring customer success and operational excellence while directly man...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$95K - $158K *

Transform the Property Intelligence platform by connecting customer needs with product insights. Collaborate across teams to enhance product adoption and engagement through analytics and feedback, dri...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Optimize regulatory compliance and legal operations in healthcare. Collaborate with cross-functional teams to ensure adherence to industry standards while driving efficiency and effectiveness in legal...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Drive your career forward by managing key customer relationships, identifying new business opportunities, and collaborating with sales teams to deliver exceptional service and solutions that create la...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$62K - $125K *

Transform the sales landscape by building your own pipeline through relentless prospecting and effective demos. Collaborate with leadership to refine strategies and drive growth in a dynamic startup e...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate customer relationships by owning a strategic account portfolio, driving growth through consultative selling and collaboration across teams. This senior role demands proactive engagement and a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Empower our growth by managing the positioning, messaging, and GTM strategy across multiple industries, ensuring impactful narratives that resonate with diverse stakeholders and drive revenue growth t...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $200K *

Elevate your career by driving strategic account growth in complex technical sales. Collaborate with top-tier clients to solve manufacturing challenges and build lasting partnerships, all while naviga...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$126K - $173K *

Shape the future of enterprise decisioning by leading cross-functional product initiatives that enhance customer experiences and drive operational readiness across multiple business channels...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$155K - $195K *

Manage the transformation of Customer Support into a strategic function, driving operational efficiency and enhancing service quality. Lead a team to implement innovative strategies that elevate the c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$154K - $221K *

Lead the charge in shaping the sales engineering team for core solutions, driving revenue growth through strategic partnerships and innovative problem-solving in a dynamic environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Lead strategic initiatives by coordinating cross-functional teams to drive major partner launches and product developments, ensuring alignment with executive priorities and measurable outcomes for com...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Shape the future of enterprise technology partnerships by driving collaboration with SAP and AWS to enhance market growth, cultivate executive relationships, and implement innovative go-to-market stra...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Lead strategic partnerships and drive revenue growth by leveraging innovative AdTech solutions. Cultivate relationships with channel partners and clients to optimize product adoption and ensure custom...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $250K *

Empower growth in the cybersecurity sector by driving sales, acquiring new accounts, and fostering strong customer relationships. Leverage your expertise to introduce innovative solutions and exceed s...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$97K - $109K *

Join a team that's redefining customer engagement by providing technical expertise and tailored solutions during the pre-sales process. Collaborate with sales and services to ensure seamless transitio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Drive enterprise growth by strategically engaging high-value accounts, orchestrating complex sales processes, and leveraging AI capabilities to enhance compliance workflows. Build executive relationsh...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.