Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$125K - $150K *

Drive enterprise sales by building relationships and closing multi-million-dollar contracts. Collaborate with cross-functional teams to deliver tailored IT solutions, ensuring client satisfaction and...

Today

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$80K - $95K *

Unlock your potential by leveraging consultative sales techniques to drive Managed Network Services and SD-WAN solutions. Collaborate with sales teams to enhance client communication and identify upse...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Elevate your career by driving sales and building relationships in the beverage industry. You'll lead initiatives that enhance visibility and engagement, while identifying growth opportunities across...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$210K - $265K *

Champion the future of our Sales organization by partnering with senior leaders to drive talent strategies, enhance organizational design, and foster a high-performance culture that scales with our ev...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Champion the Brand P&L by leading strategic marketing initiatives, enhancing brand visibility, and achieving sales targets in the Home and Garden sector through omnichannel strategies and data-driven...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$135K - $159K *

Unlock potential by driving client outreach and proposals, converting new partners to the platform. Own complex sales cycles, build executive relationships, and leverage AI-driven strategies to enhanc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$90K - $110K *

Drive market growth by managing a robust order funnel, collaborating with sales teams and partners to exceed revenue targets while developing strategic account plans and maintaining strong customer re...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$150K - $180K *

Transform the SAP sales landscape by leveraging your extensive network and expertise to drive new business acquisition in the manufacturing sector. Own the full sales cycle, from lead generation to cl...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$300K - $325K *

Drive your career with a strategic leadership role focused on enhancing marketing initiatives, optimizing client engagement, and achieving commercial growth across diverse financial services sectors...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$94K - $148K *

Join a team that's redefining technology sourcing strategies to drive savings and innovation. Lead cross-functional collaboration, manage supplier performance, and coach a talented team to optimize te...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive financial performance by analyzing regional operations and partnering with leaders to enhance profitability and efficiency across a multi-site manufacturing network. Leverage insights for strate...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$167K - $245K *

Accelerate IT innovation by leading operations and engineering teams that enhance productivity and security for a 500+ remote workforce, while embedding AI and automation into core processes for optim...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Information Technology

$40K - $200K *

Join a dynamic team to drive business growth through consultative sales, building lasting client relationships, and delivering innovative payment solutions. This role offers uncapped earnings and oppo...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$210K - $250K *

Shape the future of patient access by leading integrated strategies that enhance customer engagement and optimize portfolio performance across diverse healthcare channels, driving sustainable growth a...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Engage with strategic Oracle customers to drive success through relationship management, implementation guidance, and value realization. Champion customer outcomes and optimize their journey with Redw...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Transportation

$225K - $295K *

Transform your career by leading global logistics and fulfillment strategies. Drive efficiency in inventory management, optimize costs, and enhance service levels while collaborating with cross-functi...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$141K - $189K *

Join a dynamic team to drive strategic growth within the Department of Veterans Affairs, leveraging your expertise to build relationships, execute account strategies, and navigate complex procurement...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$210K - $250K *

Champion the evolution of HR Business Partnering globally, driving strategic workforce initiatives and organizational effectiveness while partnering with senior leaders to enhance talent and leadershi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $215K *

Unlock potential by driving organic growth in strategic accounts through deep relationships, cross-portfolio selling, and long-term planning to maximize revenue and customer retention while navigating...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join us in driving growth by acquiring new customers and expanding existing relationships. This field-oriented role requires a motivated hunter skilled in building pipelines and fostering executive co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $145K *

Elevate operational excellence by leading technical escalation and onboarding teams in Managed Services. Drive high-quality service delivery across voice, SD-WAN, and security, ensuring seamless custo...

1 week ago

  •   8 - 10 years exp.  •   Transportation

$116K - $145K *

Join a team that's redefining managed services by leading technical escalations and customer onboarding for voice services. Drive operational excellence and ensure high-quality service delivery across...

1 week ago

  •   8 - 10 years exp.  •   Transportation

$100K - $122K *

Take ownership of financial planning and analysis for G&A expenses, driving insights and reporting for senior leadership. Collaborate with teams to enhance budgeting, forecasting, and variance analysi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Develop and execute innovative product strategies for a global Oil-Flooded compressor portfolio, driving profitable growth through customer insights and cross-functional collaboration to enhance marke...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $170K *

Lead a dynamic sales team to drive innovative HIV treatment strategies. Collaborate with healthcare professionals to develop actionable business plans, foster key relationships, and achieve performanc...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.