Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$98K - $115K *
Shape the future of talent acquisition by developing strategic recruitment plans, sourcing top candidates, and partnering with hiring managers to enhance the hiring process, ensuring a positive candid...
3 weeks ago
Product Manager, File and Remit
$120K - $145K *
Transform the future of tax compliance by building a scalable filing platform and remittance infrastructure, enabling seamless global transactions and automation for international sellers. Drive innov...
4 weeks ago
Director, Business Operations & Account Management
$125K - $150K *
Shape and elevate business operations and account management, driving resource optimization and client satisfaction. Collaborate with leadership to enhance project delivery and expand client relations...
1 week ago
$100K *
Empower growth by exceeding sales quotas and presenting innovative HCM/WFM solutions. Collaborate with decision-makers to identify opportunities and tailor proposals, driving success in a dynamic sale...
2 weeks ago
Director, Franchise Operations - United West
$145K - $169K *
Transform business outcomes by leading franchise operations, driving growth, and executing strategic plans across diverse markets. Collaborate with teams to enhance performance and ensure alignment wi...
4 days ago
Director of Licensing & Enrollment
$123K - $169K *
Elevate your career by providing strategic oversight for licensing, enrollment, and credentialing operations. Lead initiatives that ensure compliance and enhance organizational capabilities while coll...
Today
Executive Director, Translational Medicine & Pediatric Planning
$246K - $332K *
Drive pediatric development strategy by integrating clinical insights and regulatory commitments across multiple therapeutic areas, ensuring effective execution from candidate transition to post-marke...
2 weeks ago
Bilingual Spanish English Sales Representative
$75K - $100K *
Unlock potential by joining a dynamic team as a bilingual sales representative, guiding clients through Medicare Health, Life, and Supplemental Insurance options in a fast-paced, supportive environmen...
5 days ago
Strategic Business Developer 5
$120K - $145K *
Shape the future of avionics sales by leading business development efforts, engaging military and commercial aerospace customers, and driving strategic growth in the Americas through innovative test s...
1 week ago
$100K - $120K *
Champion the proposal management process by leading complex RFP responses, ensuring compliance and quality. Collaborate with cross-functional teams to deliver compelling proposals that align with stra...
2 weeks ago
$80K - $125K *
Lead innovative product marketing strategies to empower financial advisors. Collaborate cross-functionally to translate complex solutions into clear value propositions, driving adoption and enhancing...
Today
$95K - $115K *
Join our dynamic team as a Finance Manager, where you'll lead financial analysis, develop models, and present insights to senior leadership, driving growth and accuracy in financial reporting across t...
4 days ago
Senior Vice President, Human Resources and Safety
$200K - $230K *
Lead the charge in shaping a people-first culture by aligning HR strategies with organizational goals, enhancing talent development, and fostering a collaborative environment across multiple sites and...
1 week ago
Vice President Field Operations
$172K - $223K *
Champion operational excellence as a strategic leader, driving performance and financial results across the PacWest Region while ensuring safety, quality, and compliance in a mission-driven environmen...
2 weeks ago
Vice President of Growth Marketing
$160K - $200K *
Unlock your potential as a strategic leader driving growth through innovative marketing strategies. Collaborate with teams to enhance demand generation and optimize performance, ensuring alignment wit...
2 weeks ago
$80K - $95K *
Empower legal executives by driving membership growth through strategic outreach, leveraging AI tools, and maintaining deep industry insights to enhance engagement and conversion rates in a dynamic, f...
4 weeks ago
$90K - $110K *
Engage with clients, driving success in digital campaign execution. Become an expert in programmatic advertising processes, enhancing customer satisfaction through effective communication and collabor...
Reposted 3 weeks ago
Senior Director, Client Success
$150K - $180K *
Reimagine client partnerships by managing complex relationships, driving performance, and leading recovery strategies. Collaborate with executives to ensure client success and identify growth opportun...
3 weeks ago
$100K - $120K *
Accelerate progress at driving new business growth in IP services by engaging corporate IP departments and legal teams. Leverage consultative selling to expand accounts and build lasting relationships...
5 days ago
$160K - $200K *
Shape and drive commercial strategies to enhance revenue growth and client relationships across diverse consumer brand sectors. Collaborate with teams to ensure client satisfaction while identifying n...
Reposted today
Regional Sales Manager, Sports Surgical - Midwest
$134K - $216K *
Lead the charge in driving sales strategies and operations for a premier MedTech portfolio. Oversee a diverse sales team, enhance customer relationships, and achieve growth targets while ensuring comp...
Today
Director of Engineering, Product
$250K - $290K *
Elevate your career by leading a high-performing engineering team, driving strategy and innovation in web3 technologies. Shape the future of decentralized systems while ensuring top-tier security and...
Reposted today
$80K - $90K *
Drive growth by engaging prospects and generating opportunities in a dynamic sales environment. Leverage your B2B sales expertise to impact pipeline and contribute to the success of innovative EdTech...
4 days ago
Director, 211 Manufacturing Quality and Regulatory Affairs
$190K - $228K *
Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...
Reposted 2 weeks ago
Regional Sales Manager, Federal System Integrators
$272K - $374K *
Empower our sales team to drive revenue growth by leading strategic engagements with Federal Systems Integrators. Utilize your expertise to craft account plans, build relationships, and navigate compl...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.