Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$100K - $120K *

Transform data into actionable insights by leading analytics solutions that drive decision-making and improve performance. Collaborate across functions to establish trusted metrics and promote self-se...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$134K - $249K *

Shape the future of vendor management by leading strategic partnerships, ensuring compliance, and optimizing performance across dental, vision, pharmacy, and transportation services, all while managin...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$164K - $225K *

Champion enterprise transformation by leading cross-functional initiatives, ensuring governance and execution quality across value-streams. Collaborate with leaders to drive measurable outcomes and bu...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$148K - $313K *

Unlock potential by serving as a strategic advisor to enterprise clients, guiding them in architecting AI-first solutions within the Life Sciences sector, while driving internal initiatives and enhanc...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $157K *

Shape the future of enterprise sales by driving innovative strategies, fostering relationships, and generating revenue through a proactive approach in a dynamic, remote environment focused on large mu...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$139K - $209K *

Join a team that's shaping strategic direction and driving execution across markets. This hands-on role requires analytical credibility and strong relationships to influence decisions and achieve meas...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $295K *

Lead the charge in optimizing global delivery operations, ensuring seamless hub economics and resource allocation. Collaborate with finance and commercial teams to drive data-driven decisions and main...

Reposted today

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Develop and execute national sales strategies to drive growth in industrial networking and cybersecurity. Build relationships, identify opportunities, and deliver tailored solutions to clients in crit...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$135K - $160K *

Lead the charge in driving operational excellence and market growth. As a senior leader, you'll oversee performance, customer relationships, and team development, ensuring alignment with strategic goa...

Reposted today

  •   8 - 10 years exp.  •   Real Estate & Construction

$125K - $175K *

Join a dynamic team to drive financial strategy and insights, ensuring sound decision-making across high-priority projects. Collaborate with leadership to optimize performance and support innovative p...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$169K - $298K *

Join a team that's driving growth by identifying key opportunities and leading cross-functional initiatives across Marketing, Product, Sales, and Engineering, ensuring teams execute with clarity to ma...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$157K - $197K *

Unlock potential by driving revenue growth through new customer acquisition and market expansion. This strategic role focuses on building executive relationships, executing targeted penetration strate...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $135K *

Champion the growth of partnerships in the public safety sector, harnessing your sales expertise to cultivate high-level relationships, create member benefits, and drive innovative solutions that enha...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$83K - $155K *

Contribute to the success of hygienic sensors by owning product strategy, collaborating with engineering, and driving market insights into actionable requirements. Lead product launches and manage lif...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $190K *

Elevate regulatory intelligence by translating complex changes into actionable insights, guiding product strategy and marketing efforts while establishing thought leadership and fostering relationship...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Accelerate progress at enterprise-level accounts by driving new-logo acquisition and managing a strategic territory plan. Engage C-suite stakeholders and lead complex sales cycles to achieve significa...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$230K - $345K *

Transform clinical trial management by leading early-phase oncology programs. Drive strategic vision, operational excellence, and cross-functional collaboration to ensure timely, budget-compliant exec...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Accelerate progress at a multinational level by driving the reward and global mobility agenda. Lead the design and governance of compensation structures, ensuring alignment with business needs while p...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$250K - $350K *

Transform high-ticket sales by conducting inbound evaluation calls with pre-qualified prospects. Engage in deep discovery conversations, present exclusive membership, and enroll elite real estate prof...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Empower enterprise growth by collaborating with Sales Leadership to optimize strategies, manage performance, and enhance sales processes. Drive data-driven decisions and build scalable systems that el...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$125K - $145K *

Drive product strategy and modernization for merchant onboarding solutions, collaborating with cross-functional teams to enhance risk management capabilities and ensure market-leading standards in a d...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Drive strategic initiatives to uncover and expand business opportunities, generating new sales through targeted contracts and executive-level relationships while mentoring sales teams and managing cus...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Join our team to drive sales across innovative solutions, engaging with HR and finance stakeholders. You'll build pipelines, close deals, and shape our market approach for new products, all while coll...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$190K *

Reimagine consumer experiences by leading product strategy and technology development for digital platforms. Drive innovation and enhance customer engagement through seamless interactions and data-dri...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$135K - $160K *

Champion the transformation of web initiatives into impactful projects, overseeing the entire lifecycle from planning to launch. Collaborate with cross-functional teams to enhance user experience and...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.