Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Manager, Home Center Analytics Enablement
$100K - $120K *
Transform data into actionable insights by leading analytics solutions that drive decision-making and improve performance. Collaborate across functions to establish trusted metrics and promote self-se...
3 weeks ago
Senior Director, Vendor Partnerships
$134K - $249K *
Shape the future of vendor management by leading strategic partnerships, ensuring compliance, and optimizing performance across dental, vision, pharmacy, and transportation services, all while managin...
Today
Director, Value Stream Transformation
$164K - $225K *
Champion enterprise transformation by leading cross-functional initiatives, ensuring governance and execution quality across value-streams. Collaborate with leaders to drive measurable outcomes and bu...
2 weeks ago
Salesforce Senior/ Director Technical Architect, FINS/LSC
$148K - $313K *
Unlock potential by serving as a strategic advisor to enterprise clients, guiding them in architecting AI-first solutions within the Life Sciences sector, while driving internal initiatives and enhanc...
Reposted 1 week ago
Enterprise Account Director, New Business (API/CPaaS)
$120K - $157K *
Shape the future of enterprise sales by driving innovative strategies, fostering relationships, and generating revenue through a proactive approach in a dynamic, remote environment focused on large mu...
4 weeks ago
$139K - $209K *
Join a team that's shaping strategic direction and driving execution across markets. This hands-on role requires analytical credibility and strong relationships to influence decisions and achieve meas...
Today
Managing Director Global Delivery (Hub)
$125K - $295K *
Lead the charge in optimizing global delivery operations, ensuring seamless hub economics and resource allocation. Collaborate with finance and commercial teams to drive data-driven decisions and main...
Reposted today
Business Development Manager - INCS
$110K - $130K *
Develop and execute national sales strategies to drive growth in industrial networking and cybersecurity. Build relationships, identify opportunities, and deliver tailored solutions to clients in crit...
2 weeks ago
General Manager - Marick Mechanical (St. Louis, MO)
$135K - $160K *
Lead the charge in driving operational excellence and market growth. As a senior leader, you'll oversee performance, customer relationships, and team development, ensuring alignment with strategic goa...
Reposted today
$125K - $175K *
Join a dynamic team to drive financial strategy and insights, ensuring sound decision-making across high-priority projects. Collaborate with leadership to optimize performance and support innovative p...
2 weeks ago
Director, Strategy & Operations, Consumer
$169K - $298K *
Join a team that's driving growth by identifying key opportunities and leading cross-functional initiatives across Marketing, Product, Sales, and Engineering, ensuring teams execute with clarity to ma...
Reposted today
Principal Business Development Manager
$157K - $197K *
Unlock potential by driving revenue growth through new customer acquisition and market expansion. This strategic role focuses on building executive relationships, executing targeted penetration strate...
3 weeks ago
Senior Business Development - Public Safety
$120K - $135K *
Champion the growth of partnerships in the public safety sector, harnessing your sales expertise to cultivate high-level relationships, create member benefits, and drive innovative solutions that enha...
Reposted 3 weeks ago
$83K - $155K *
Contribute to the success of hygienic sensors by owning product strategy, collaborating with engineering, and driving market insights into actionable requirements. Lead product launches and manage lif...
1 week ago
Senior Director, Regulatory & Industry Intelligence
$160K - $190K *
Elevate regulatory intelligence by translating complex changes into actionable insights, guiding product strategy and marketing efforts while establishing thought leadership and fostering relationship...
4 days ago
Account Executive, Enterprise (Acquisition) - Midwest
$125K - $150K *
Accelerate progress at enterprise-level accounts by driving new-logo acquisition and managing a strategic territory plan. Engage C-suite stakeholders and lead complex sales cycles to achieve significa...
Yesterday
Senior Director, Early Oncology
$230K - $345K *
Transform clinical trial management by leading early-phase oncology programs. Drive strategic vision, operational excellence, and cross-functional collaboration to ensure timely, budget-compliant exec...
6 days ago
Senior Reward & Mobility Manager
$180K - $200K *
Accelerate progress at a multinational level by driving the reward and global mobility agenda. Lead the design and governance of compensation structures, ensuring alignment with business needs while p...
Reposted 1 week ago
Account Executive (High-Ticket Sales)
$250K - $350K *
Transform high-ticket sales by conducting inbound evaluation calls with pre-qualified prospects. Engage in deep discovery conversations, present exclusive membership, and enroll elite real estate prof...
4 weeks ago
Sales Strategy & Operations, Enterprise
$120K - $145K *
Empower enterprise growth by collaborating with Sales Leadership to optimize strategies, manage performance, and enhance sales processes. Drive data-driven decisions and build scalable systems that el...
Yesterday
$125K - $145K *
Drive product strategy and modernization for merchant onboarding solutions, collaborating with cross-functional teams to enhance risk management capabilities and ensure market-leading standards in a d...
Reposted 1 week ago
$100K - $120K *
Drive strategic initiatives to uncover and expand business opportunities, generating new sales through targeted contracts and executive-level relationships while mentoring sales teams and managing cus...
4 weeks ago
$90K - $110K *
Join our team to drive sales across innovative solutions, engaging with HR and finance stakeholders. You'll build pipelines, close deals, and shape our market approach for new products, all while coll...
Yesterday
VP, Consumer Experience Technology
$190K *
Reimagine consumer experiences by leading product strategy and technology development for digital platforms. Drive innovation and enhance customer engagement through seamless interactions and data-dri...
6 days ago
Principal Product Manager, Web
$135K - $160K *
Champion the transformation of web initiatives into impactful projects, overseeing the entire lifecycle from planning to launch. Collaborate with cross-functional teams to enhance user experience and...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.