Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$110K - $130K *

Drive new business growth by leveraging your SaaS sales expertise. Engage with property management companies, manage the full sales cycle, and collaborate cross-functionally to ensure client success i...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Transform branch operations by leading a dynamic team to enhance customer service, drive sales, and ensure profitability while maintaining safety and compliance standards. Your leadership will shape t...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$183K - $220K *

Lead strategic initiatives for Integrated Delivery Networks and health systems, optimizing patient access and formulary adoption. Build executive relationships and drive clinical integration to enhanc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $250K *

Lead strategic partnerships with cloud providers to drive co-sell initiatives, enhance pipeline generation, and foster deep relationships with key stakeholders, ensuring alignment between internal sal...

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$190K - $250K *

Drive growth by managing strategic cloud partnerships, aligning sales strategies, and executing co-sell initiatives to enhance pipeline and revenue. Collaborate with internal teams and cloud partners...

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Champion sales excellence by leading a dynamic team to drive MRD testing growth. Develop strategic business plans, foster key relationships, and ensure operational success across multiple states while...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Lead the charge in enterprise sales by hunting new logos within the Life Sciences sector. Build relationships with Salesforce partners to enhance co-selling opportunities while managing your own pipel...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$91K - $121K *

Elevate the commercialization process across the product portfolio, enhancing efficiency and data integrity. Lead cross-functional collaboration, implement automation innovations, and drive strategic...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$62K - $103K *

Empower growth by maximizing revenue through strategic account management and sales development. Collaborate with military clients to enhance operations and drive profitable sales while adapting to ev...

4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $200K *

Lead the charge in developing integrated media strategies and client partnerships across pharmaceutical and life sciences accounts, driving business growth and ensuring exceptional delivery and client...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Partner with us to enhance client relationships and drive growth. In this role, you'll manage a diverse portfolio, ensuring customer retention and identifying new opportunities while collaborating wit...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$150K *

Drive occupancy and sales success in a vibrant senior living community. Engage with potential residents and families, fostering meaningful connections while achieving targets in a supportive, mission...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$177K - $221K *

Champion global revenue accounting policies and lead technical assessments across U.S. and international markets, ensuring compliance with U.S. GAAP and SEC reporting while collaborating with regional...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$146K - $178K *

Shape the future of biopharma by leading commercial strategy engagements, guiding clients through critical launch decisions, and delivering evidence-based recommendations to drive success in a dynamic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower frontline workers by owning the full sales cycle in a dynamic team. Drive impactful solutions, build relationships, and refine strategies to scale success in a fast-paced environment. Your con...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$220K - $320K *

Champion new customer acquisition by leading the full enterprise sales cycle, building relationships with senior decision-makers, and delivering compelling business cases in highly regulated industrie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$219K - $285K *

Lead a regional team of MSLs to drive scientific engagement and strategy execution. Collaborate with stakeholders to enhance field medical excellence and ensure alignment with corporate objectives whi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $115K *

Lead financial pricing strategies and support sales operations through analytical insights, forecasting, and continuous improvement initiatives. Collaborate with cross-functional teams to optimize mar...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$150K - $180K *

Inspire growth by leading strategic initiatives for key telecom accounts, fostering executive relationships, and driving multi-year revenue plans. Collaborate across teams to align solutions with evol...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$110K - $130K *

Join a team that's driving strategic growth through partnerships with GSIs, MSPs, and VARs. This role combines relationship building, market strategy, and sales leadership to generate revenue and opti...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Optimize client relationships by managing key accounts and driving growth through strategic sales initiatives. Collaborate with internal teams to enhance customer experience and ensure long-term succe...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$90K - $100K *

Unlock your potential by driving sales of retirement plans in a dynamic market. Build relationships with financial intermediaries and plan sponsors while managing a targeted territory to achieve ambit...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $132K *

Join a team that's transforming service operations for utility-scale energy storage systems. Oversee inventory, warranty processes, and warehouse logistics to ensure customer satisfaction and operatio...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$62K - $146K *

Inspire a high-performing sales organization by leading and developing Sales Managers across a multi-agency territory, driving revenue growth, and shaping the future of your district while enhancing c...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's dedicated to enhancing client relationships and driving revenue growth. You'll manage sourcing, production, and inventory while collaborating with executives to identify new sales o...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.