Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$110K - $130K *
Drive new business growth by leveraging your SaaS sales expertise. Engage with property management companies, manage the full sales cycle, and collaborate cross-functionally to ensure client success i...
Today
$80K - $95K *
Transform branch operations by leading a dynamic team to enhance customer service, drive sales, and ensure profitability while maintaining safety and compliance standards. Your leadership will shape t...
2 weeks ago
$183K - $220K *
Lead strategic initiatives for Integrated Delivery Networks and health systems, optimizing patient access and formulary adoption. Build executive relationships and drive clinical integration to enhanc...
1 week ago
$190K - $250K *
Lead strategic partnerships with cloud providers to drive co-sell initiatives, enhance pipeline generation, and foster deep relationships with key stakeholders, ensuring alignment between internal sal...
5 days ago
$190K - $250K *
Drive growth by managing strategic cloud partnerships, aligning sales strategies, and executing co-sell initiatives to enhance pipeline and revenue. Collaborate with internal teams and cloud partners...
5 days ago
MRD Regional Sales Director, St. Louis/Indianapolis
$150K - $200K *
Champion sales excellence by leading a dynamic team to drive MRD testing growth. Develop strategic business plans, foster key relationships, and ensure operational success across multiple states while...
1 week ago
$125K - $150K *
Lead the charge in enterprise sales by hunting new logos within the Life Sciences sector. Build relationships with Salesforce partners to enhance co-selling opportunities while managing your own pipel...
1 week ago
$91K - $121K *
Elevate the commercialization process across the product portfolio, enhancing efficiency and data integrity. Lead cross-functional collaboration, implement automation innovations, and drive strategic...
Reposted 3 days ago
$62K - $103K *
Empower growth by maximizing revenue through strategic account management and sales development. Collaborate with military clients to enhance operations and drive profitable sales while adapting to ev...
4 days ago
Group Director, Client Media Solutions
$175K - $200K *
Lead the charge in developing integrated media strategies and client partnerships across pharmaceutical and life sciences accounts, driving business growth and ensuring exceptional delivery and client...
2 weeks ago
$100K - $120K *
Partner with us to enhance client relationships and drive growth. In this role, you'll manage a diverse portfolio, ensuring customer retention and identifying new opportunities while collaborating wit...
4 weeks ago
Senior Living Sales Director - St. Anthony's
$150K *
Drive occupancy and sales success in a vibrant senior living community. Engage with potential residents and families, fostering meaningful connections while achieving targets in a supportive, mission...
1 week ago
Associate Director, Global Revenue, Technical Accounting & Reporting
$177K - $221K *
Champion global revenue accounting policies and lead technical assessments across U.S. and international markets, ensuring compliance with U.S. GAAP and SEC reporting while collaborating with regional...
3 weeks ago
Associate Director Commercial Strategy and Planning
$146K - $178K *
Shape the future of biopharma by leading commercial strategy engagements, guiding clients through critical launch decisions, and delivering evidence-based recommendations to drive success in a dynamic...
1 week ago
Founding Account Executive (West Coast)
$80K - $95K *
Empower frontline workers by owning the full sales cycle in a dynamic team. Drive impactful solutions, build relationships, and refine strategies to scale success in a fast-paced environment. Your con...
2 weeks ago
$220K - $320K *
Champion new customer acquisition by leading the full enterprise sales cycle, building relationships with senior decision-makers, and delivering compelling business cases in highly regulated industrie...
2 weeks ago
Senior Regional Director, Medical Science Liaisons – East
$219K - $285K *
Lead a regional team of MSLs to drive scientific engagement and strategy execution. Collaborate with stakeholders to enhance field medical excellence and ensure alignment with corporate objectives whi...
Yesterday
Manager Pricing - Retail, Technology, Healthcare
$105K - $115K *
Lead financial pricing strategies and support sales operations through analytical insights, forecasting, and continuous improvement initiatives. Collaborate with cross-functional teams to optimize mar...
2 weeks ago
North America Digital Solutions Key Account Director
$150K - $180K *
Inspire growth by leading strategic initiatives for key telecom accounts, fostering executive relationships, and driving multi-year revenue plans. Collaborate across teams to align solutions with evol...
3 weeks ago
$110K - $130K *
Join a team that's driving strategic growth through partnerships with GSIs, MSPs, and VARs. This role combines relationship building, market strategy, and sales leadership to generate revenue and opti...
Reposted 3 weeks ago
Account Manager- Central Florida
$125K - $150K *
Optimize client relationships by managing key accounts and driving growth through strategic sales initiatives. Collaborate with internal teams to enhance customer experience and ensure long-term succe...
Reposted 1 week ago
Regional Vice President - Retirement Mid Markets (Washington)
$90K - $100K *
Unlock your potential by driving sales of retirement plans in a dynamic market. Build relationships with financial intermediaries and plan sponsors while managing a targeted territory to achieve ambit...
4 weeks ago
$105K - $132K *
Join a team that's transforming service operations for utility-scale energy storage systems. Oversee inventory, warranty processes, and warehouse logistics to ensure customer satisfaction and operatio...
4 weeks ago
District Manager, Life Insurance (Region 10_District 053)
$62K - $146K *
Inspire a high-performing sales organization by leading and developing Sales Managers across a multi-agency territory, driving revenue growth, and shaping the future of your district while enhancing c...
2 weeks ago
$80K - $95K *
Join a team that's dedicated to enhancing client relationships and driving revenue growth. You'll manage sourcing, production, and inventory while collaborating with executives to identify new sales o...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.