Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$110K - $130K *

Unlock potential by leading cross-functional initiatives to enhance caregiver enrollment technology. Drive strategy, optimize user experiences, and leverage data analytics to achieve growth in a dynam...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Transform business growth by leading global strategies, driving market opportunities, and fostering cross-functional collaboration to enhance profitability and market share in the oil & gas and proces...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$140K - $170K *

Shape the future of sales strategy across the Americas, leading a high-performing team to drive revenue growth through direct and indirect channels while collaborating with cross-functional teams to a...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$325K - $400K *

Join a team that's driving revenue growth in Northern California by leading a high-performing sales organization, developing strategic partnerships, and executing innovative go-to-market strategies in...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $140K *

Drive efficiency and scalability in onboarding processes, enhancing customer experience through innovative strategies and data-driven leadership. Lead a high-performing team to optimize resources and...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$150K - $200K *

Drive strategic revenue growth by engaging C-suite stakeholders and closing multimillion-dollar partnerships within large pharmaceutical organizations. Leverage your expertise to navigate complex sale...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$350K - $500K *

Lead the charge in driving global revenue and sales strategies across ORACLE Services. Oversee renewals and new client invoicing while collaborating cross-functionally to achieve aggressive growth tar...

United StatesRemote

Reposted 3 weeks ago

  •   15+ years exp.  •   Enterprise Technology

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$165K - $235K *

Drive the execution of DSO growth strategies, leading a team to achieve revenue targets through data-driven sales and cross-functional collaboration, while enhancing customer relationships and ensurin...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $230K *

Lead customer success initiatives by managing federal program delivery, ensuring seamless deployment, support, and renewal processes. Drive team performance and build strategic partnerships to enhance...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Empower your career by leading Channel Operations to enhance partner engagement, drive operational excellence, and foster team performance. Collaborate cross-functionally to maximize value and achieve...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Unlock insights and drive performance as you analyze data, develop countermeasures, and execute strategies in the field. Collaborate with sales teams to enhance dealer activation and reduce churn, ens...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$146K - $182K *

Design and deliver impactful training programs to enhance sales capabilities, ensuring alignment with corporate objectives. Collaborate with cross-functional teams to drive effective onboarding and co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Lead the charge in driving business development for Technical Flooring, identifying new opportunities, cultivating strategic partnerships, and enhancing client relationships to achieve growth and prof...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Lead a dynamic sales team to drive growth and profitability in your territory. Develop strategic sales plans, enhance customer retention, and optimize performance through effective collaboration and i...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Elevate your career by leading global Food Safety operations, driving strategy, and enhancing performance across multiple manufacturing sites. Collaborate with cross-functional teams to ensure safety...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $140K *

Engage with Private Equity firms to develop strategic partnerships, promoting supply chain services and driving revenue growth through effective channel management and collaboration with stakeholders...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Shape the future of lacrosse ministry by providing leadership, support, and strategic direction to field teams, enhancing program impact and disciple-making across FCA's initiatives...

3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $130K *

Accelerate progress at client acquisition through strategic sales initiatives, fostering relationships, and managing accounts in the Northeast. Drive revenue growth while utilizing CRM tools and AI to...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $96K *

Drive your sales career forward by leading a dynamic team, building client relationships, and implementing proven strategies. Enjoy flexibility while mentoring others and providing tailored insurance...

Reposted yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$86K - $138K *

Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Advance your career by leading a high-performing sales team in the luxury automotive sector. Drive operational excellence, enhance customer experiences, and implement strategic sales initiatives to ac...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Drive the future of outside sales by leading a dynamic team, building client relationships, and implementing proven strategies. Enjoy flexibility in your schedule while mentoring new talent and enhanc...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Join a dynamic team as you lead outside sales efforts, mentoring new talent while managing client relationships. Leverage your extensive sales experience to drive growth and deliver tailored insurance...

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.