Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$150K - $180K *

Drive new logo acquisition and revenue growth in the healthcare sector by leading complex sales processes, building executive relationships, and collaborating with cross-functional teams to deliver ta...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$295K - $325K *

Drive strategic sales leadership across the Western US, translating brand vision into effective field execution. Build and sustain a high-performing team while collaborating cross-functionally to achi...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Accelerate growth by driving revenue through strategic sales of a digital payment platform to insurance carriers. Engage with C-level executives to foster relationships that enhance long-term success...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by driving growth through strategic partnerships in the TSD ecosystem. This role focuses on recruiting and managing Trusted Advisors, generating opportunities, and collaborating wi...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $146K *

Innovate strategic partnerships and drive revenue growth in NTN and IoT sectors. Cultivate relationships with global carriers, negotiate agreements, and identify new business opportunities to establis...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$132K - $221K *

Drive enterprise-wide legal support for global contracting activities, focusing on procurement and technology transactions. Collaborate with cross-functional teams to manage risks and ensure complianc...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $200K *

Unlock potential by overseeing large-scale data center construction projects, ensuring timely delivery, budget adherence, and quality standards while collaborating with diverse stakeholders across all...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$125K - $150K *

Shape the future of financial advisory by leading and developing a high-performing team. Drive growth, elevate client experiences, and build a culture of excellence, integrity, and ambition...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $150K *

Unlock potential by driving sales of innovative POS systems to liquor stores. Engage with small business owners, modernizing their operations through technology while achieving high rewards in a dynam...

4 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Unlock your potential by leading a dynamic sales team to drive growth in the school transportation market. Build strategic relationships, shape sales strategies, and ensure product excellence while ma...

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$190K - $280K *

Transform talent acquisition by leading a global team to enhance recruiting efficiency, drive strategy, and leverage AI for measurable improvements across diverse markets while ensuring compliance and...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Grow your career with a dynamic sales role focused on driving growth in industrial manufacturing. Engage with customers, manage the sales process, and achieve targets while building lasting relationsh...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $120K *

Empower growth by managing and expanding relationships in North American Industrial, Academic, Pharmaceutical, and Biotech markets through proactive sales strategies and digital engagement...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$141K - $207K *

Grow the Bank’s profitability by cultivating and expanding commercial relationships. Collaborate with clients to understand their financial needs and leverage your credit acumen to provide tailored ba...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$202K - $250K *

Champion data-driven decision-making by leading the development of integrated analytics and reporting strategies. Drive operational efficiency and financial performance through innovative data solutio...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$172K - $287K *

Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...

RemoteRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$230K - $285K *

Champion technology strategy and innovation across Health and Defense sectors. Lead enterprise technology direction, drive execution of solutions, and establish strategic partnerships to enhance compe...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $120K *

Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Shape the future of Endpoint Security by leading product strategy, driving innovation, and ensuring financial growth. Collaborate cross-functionally to enhance product performance and market positioni...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Join a dynamic team to lead product strategy and innovation for cutting-edge cloud solutions, driving customer-centric development and measurable growth within the legal technology space. Shape the fu...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $190K *

Manage strategic sales relationships with national accounts to drive growth in value-based care. Collaborate with leadership teams, execute contract strategies, and support implementations to enhance...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$105K - $120K *

Help us drive sales growth and enhance community partnerships by leading a dynamic sales team focused on expanding market share and improving patient registrations in the healthcare sector...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $235K *

Transform public safety operations by driving growth through strategic sales and relationship-building with fire departments and agencies. Own the sales cycle, deliver impactful demos, and collaborate...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $225K *

Unlock growth by leading strategic partnerships in the CDMO sector. Drive sales, nurture client relationships, and collaborate across teams to enhance market presence and customer satisfaction. Your e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's driving growth in mid-market healthcare by building relationships, managing a dynamic sales pipeline, and closing new business opportunities in a fast-paced SaaS environment...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.