Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$160K - $190K *
Empower nonprofit organizations to maximize their impact by leading product strategy and execution for innovative fundraising solutions. Drive growth through deep customer insights, collaborative part...
Reposted 2 weeks ago
Account Executive (CPQ Solutions)
$135K - $200K *
Unlock potential by driving customer growth and engagement through consultative selling, leveraging AI insights to enhance account strategies and foster strong relationships with existing clients and...
3 weeks ago
$95K - $115K *
Engage with key strategic customers to foster relationships and drive growth. Collaborate across teams to deliver tailored solutions, ensuring customer satisfaction and long-term partnerships while ac...
6 days ago
Vice President, Operations East
$206K - $260K *
Lead multi-market operations in a fast-paced environment, ensuring safety, efficiency, and compliance while managing P&L and team performance. Drive new district launches and stabilize existing operat...
2 weeks ago
$200K - $225K *
Transform healthcare data into actionable insights by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercia...
Today
Senior Manager, Food Safety & Quality
$100K - $120K *
Join the charge in enhancing food safety and quality across multiple manufacturing sites. Lead a dedicated team, implement best practices, and foster collaboration to ensure compliance and excellence...
3 weeks ago
$170K - $200K *
Elevate tax administration services for exchange-traded funds by leading a dynamic team, resolving complex tax matters, and enhancing processes to support a growing fund platform while ensuring compli...
3 weeks ago
$160K - $200K *
Drive the M&A strategy by leading the full transaction lifecycle, from sourcing to integration. Collaborate with executive leadership to identify growth opportunities that enhance enterprise value and...
3 weeks ago
Regional Sales Director - Upstate NY
$180K - $215K *
Join us to lead regional sales efforts, driving product launch success and team performance. You'll build strong customer relationships, execute strategic plans, and foster a high-performing culture i...
Reposted today
$120K - $145K *
Transform the Sales and Customer Experience landscape by leading enablement and training initiatives. Oversee onboarding, training relevance, and cross-functional collaboration to enhance team perform...
2 weeks ago
Associate Director, Corporate Accounts - Food and Beverage (Beverage and Brewing)
$135K - $198K *
Unlock strategic growth by cultivating partnerships in the Beverage & Brewing sector. Collaborate with senior stakeholders to enhance customer success through innovative solutions, driving long-term v...
1 week ago
$150K - $180K *
Shape the future of billing operations by leading a team to enhance accuracy, timeliness, and efficiency. Drive process improvements, manage complex accounts, and collaborate across functions to resol...
1 week ago
$80K - $95K *
Transform quality assurance processes by leading the development and implementation of a robust Quality Management System (QMS) in an automotive manufacturing environment, ensuring compliance and driv...
Today
Senior Accounting Manager - Insurance
$160K - $180K *
Provide oversight for insurance accounting and reporting, driving process improvements and leveraging technology to enhance financial operations. Collaborate with teams to ensure compliance and accura...
4 weeks ago
Regional Sales Manager - Southeast
$140K *
Drive regional sales success by leading a dynamic team, achieving revenue goals, and fostering collaboration. Utilize your expertise in capital medical equipment sales to mentor Territory Managers and...
1 week ago
Vice President, CMC Regulatory Affairs
$272K - $340K *
Elevate your career by leading CMC Regulatory strategy and execution. Drive submissions, build a high-performing team, and engage with global health authorities to ensure compliance and success in dru...
2 weeks ago
Account Director, Medical Imaging and SS
$110K - $130K *
Advance your career by driving business development in clinical research and medical imaging. Build strategic client relationships, identify new opportunities, and contribute to innovative healthcare...
Reposted 2 weeks ago
Director of Growth (Recreation)
$180K - $200K *
Elevate your career by driving growth strategies that enhance lead generation for multiple brands. Collaborate with cross-functional teams to optimize acquisition channels and improve conversion rates...
Reposted today
$300K - $375K *
Elevate financial strategy and operations by leading a high-performing Finance team, driving capital allocation, and shaping the company's financial narrative to support growth and investor relations...
3 weeks ago
$80K - $95K *
Drive customer success by managing key accounts, ensuring satisfaction, and expanding revenue through upselling. Collaborate with internal teams to align customer needs with solutions, while leveragin...
2 weeks ago
$185K - $234K *
Champion client success by leading a high-performing team to drive strategic account management, enhance client loyalty, and achieve revenue targets through collaboration with cross-functional teams a...
Yesterday
$140K - $160K *
Accelerate progress at a dynamic tech firm by owning the full sales cycle for mid-market practices. Collaborate with leadership to shape strategy and drive impactful relationships, ensuring success in...
1 week ago
Pod Leader, Corporate Strategic Sales
$150K - $215K *
Elevate growth at top global accounts by leading strategic sales initiatives, building executive relationships, and driving value-based solutions. Collaborate with cross-functional teams to achieve am...
2 weeks ago
New Business Sales Executive - Western Territory
$100K - $120K *
Drive revenue growth by cultivating relationships and managing the full-cycle sales process in the healthcare technology sector. Utilize AI-driven solutions to enhance client performance and deliver v...
1 week ago
$187K - $257K *
Empower transformation initiatives by leading enterprise projects, managing stakeholder relationships, and driving strategic outcomes. Collaborate with diverse teams to define program strategies and e...
6 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.