Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Director, Business Development
$169K - $255K *
Join a team that's driving growth through strategic partnerships in personalized consumer products. Lead initiatives to expand market reach and revenue streams while collaborating across functions to...
1 week ago
$80K - $95K *
Join a team that's dedicated to excellence in food service management, overseeing multiple contracted services with a revenue range of $2-15M+. Lead operations, enhance client relationships, and drive...
4 days ago
$125K - $150K *
Manage client relationships by leading strategic planning and execution of wealth strategies. Collaborate with families and their advisors to ensure alignment with their goals while guiding a dedicate...
3 weeks ago
$102K - $180K *
Transform enterprise partnerships by driving account growth, fostering relationships, and optimizing sales processes. Collaborate with internal teams, lead post-sales management, and utilize data insi...
Reposted today
VP - Global Strategic Partnerships
$190K - $381K *
Empower global partnerships by leading strategy and execution across markets, enhancing relationships with key partners, and driving innovation in financial services. Build a high-performing team to s...
3 weeks ago
Director of Business Development - Warehousing, Distribution & 3PL Sales
$80K - $120K *
Accelerate progress at our company by driving new customer acquisition and revenue growth in warehousing and logistics. Leverage your expertise to build relationships and secure opportunities in the K...
1 week ago
Head of Fertility Sales & Business Development
$150K - $180K *
Lead national physician engagement and business development for a fertility pharmacy, managing a multi-layered team to drive growth and build executive relationships across clinics and provider networ...
1 week ago
$150K - $180K *
Innovate product management across a diverse SaaS portfolio, leading teams to enhance strategy and execution. Collaborate with executives to drive growth and operational excellence in global markets...
3 weeks ago
Regional Sales Director - Great Lakes / Ohio Valley ONLY
$140K *
Shape the future of public safety SaaS by leading a high-performing sales team, driving growth, and executing strategic initiatives in a rapidly evolving market. Collaborate cross-functionally to enha...
3 weeks ago
Sr. Director, Corporate Development
$175K - $210K *
Transform corporate growth by leading strategic partnerships and acquisitions. Drive financial analyses, develop business cases, and collaborate with stakeholders to enhance market presence and execut...
Yesterday
$130K - $150K *
Join a team that's shaping high-impact strategies and narratives for enterprise growth. Collaborate with senior leaders to craft compelling pitches and support organic initiatives, driving success acr...
Reposted 2 weeks ago
$160K - $180K *
Lead strategic health plan implementations and optimize client solutions. Drive cross-functional collaboration, manage complex projects, and enhance operational workflows to ensure successful launches...
6 days ago
Vice President, Medical Affairs
$280K - $325K *
Join a team that's transforming clinical evidence into impactful product strategies. Collaborate with cross-functional leaders to enhance healthcare solutions, drive innovation, and strengthen market...
Yesterday
$100K - $120K *
Transform financial planning by developing models, tracking expenses, and conducting analyses. Collaborate with FP&A teams to prepare cash flow projections and monthly reports, driving insights for en...
Today
$200K - $205K *
Join a team that's redefining enterprise sales by leading a diverse group of sellers to exceed quotas, drive growth, and implement innovative fraud solutions in a rapidly evolving market...
2 weeks ago
Business Development Director I, Early Drug Development
$80K - $120K *
Shape the future of Crop Protection & Chemicals by driving sales and fostering client relationships. Utilize strategic insights and collaboration to achieve targets and expand market presence while ma...
Reposted 1 week ago
$110K - $130K *
Drive efficient order management and logistics operations, ensuring compliance with pharmaceutical regulations while collaborating with internal teams and 3PL partners to optimize product flow and per...
3 weeks ago
AVP/VP, Client Services (RadScience)
$175K - $205K *
Transform client relationships and drive growth by leading strategic initiatives in scientific visualization, medical education, and digital engagement. Manage multidisciplinary teams and oversee acco...
Reposted 2 weeks ago
$125K - $150K *
Lead the charge in managing multiple sites with P&L responsibility, driving growth and operational excellence. Collaborate with teams to enhance customer satisfaction and foster a positive work enviro...
Reposted 3 weeks ago
VICE PRESIDENT, OPERATIONS (SOUTHEAST)
$180K - $220K *
Drive the future of healthcare operations by leading a $300M portfolio, fostering physician partnerships, and executing growth strategies while managing financial and operational performance for a dyn...
Reposted 1 week ago
Sales Manager, Mortgage Lending
$80K - $95K *
Optimize mortgage lending strategies by leading a team of loan originators to enhance production, drive sales performance, and develop referral partnerships, ensuring alignment with organizational goa...
2 weeks ago
Global Strategic Partnership Director
$150K - $180K *
Transform global partner strategies to drive revenue and market share through innovative go-to-market models, collaborating with key stakeholders to establish impactful partnerships and optimize sales...
2 weeks ago
Senior Manager, Deal Desk - North America
$153K *
Shape strategic transactions as the Deal Desk lead for North America, collaborating with Sales and cross-functional teams to enhance deal structure, execution, and compliance while optimizing processe...
Reposted today
Senior Product Marketing Manager
$120K - $145K *
Elevate your career by leading strategic product marketing initiatives, managing high-impact projects, and collaborating cross-functionally to drive value propositions in enterprise technology, includ...
4 weeks ago
$150K - $224K *
Shape the future of financial strategy by leading comprehensive planning, reporting, and governance processes. Drive team performance and enhance decision-making across global business units while fos...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.