Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$128K - $192K *

Unlock potential by driving new business growth through actionable health intelligence. Build relationships, identify client needs, and showcase solutions to enhance employee wellbeing and manage heal...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$150K *

Lead the charge in driving Medicare partnerships, enhancing contract value, and achieving growth targets through strategic sales initiatives and relationship management with health plans...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$164K - $305K *

Join a team that's redefining account management by driving growth and retention for complex health systems. Build strategic relationships with C-suite executives and lead cross-functional teams to de...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Analyze and optimize global GTM operations, driving strategy and execution across account planning, metrics, and AI-enabled technology to enhance revenue performance and streamline processes for maxim...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Unlock strategic leadership in affordable housing development, guiding a team to identify and execute multifamily projects. Drive growth by managing the development pipeline and ensuring alignment wit...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Real Estate & Construction

$110K *

Join a dynamic team as you oversee a 3PL distribution warehouse, ensuring safety and efficiency while managing operations, budgets, and staff. Drive excellence in customer service and lead a dedicated...

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$213K - $321K *

Lead and develop a high-performing sales team, driving regional growth through effective strategy, coaching, and relationship-building. Own forecasting and operational cadence while fostering a cultur...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $175K *

Lead the charge in driving enterprise growth by selling innovative technology and services to large employers. Own the full sales cycle, build relationships with senior decision-makers, and develop ta...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $150K *

Drive regional sales growth by leveraging brand strategies, managing broker teams, and developing customer relationships. Utilize data insights to enhance market share and profitability while achievin...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Empower your career by leading sales strategies across the US. Collaborate with a dynamic team to drive growth, develop client relationships, and deliver impactful presentations while navigating indus...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Join a team that's driving sales growth by identifying and closing new business opportunities. Leverage your customer relationship skills to expand our client base and establish lasting partnerships w...

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$100K - $250K *

Help us drive growth in the public safety market by managing sales in the Northeast. You'll develop strategies, build relationships, and close deals while collaborating with a dedicated team to achiev...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $255K *

Elevate your career by driving new business in healthcare accounts. Engage with C-level executives, navigate complex sales cycles, and close high-value deals to expand market presence and achieve reve...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Business Services

$190K - $200K *

Elevate operational excellence by leading transformation initiatives and optimizing Shared Services. Collaborate with senior leaders to drive measurable improvements in productivity, cost efficiency...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$175K - $210K *

Drive growth by owning the full sales cycle across a large western territory, collaborating closely with customer success to foster partnerships, and building relationships with healthcare leaders to...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in building and managing a new sales region, driving team performance and revenue growth across the Central US. Own recruitment, coaching, and operational excellence to ensure success...

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Elevate sales performance by developing new business opportunities in North America. Drive customer acquisition through tailored MES & ERP solutions while managing the full sales cycle and collaborati...

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Champion strategic marketing initiatives to drive growth in North America. Collaborate with cross-functional teams to develop market strategies, analyze trends, and enhance customer engagement, ensuri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$190K - $220K *

Champion financial excellence by leading a dynamic team, driving strategic analysis, and leveraging AI to enhance decision-making for a diverse portfolio of clients in a fast-paced, remote environment...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$150K - $180K *

Grow your career with a pivotal role bridging client challenges and omnichannel solutions. Lead strategic discovery, design tailored solutions, and drive impactful pilots to showcase value, ensuring a...

Reposted yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $160K *

Manage and inspire a high-performing sales team to drive revenue growth and customer satisfaction within assigned accounts. Cultivate strategic relationships, oversee contract compliance, and develop...

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$122K - $163K *

Elevate sales performance by leading a diverse team, driving strategic initiatives, and fostering customer relationships to achieve revenue growth and market penetration in a dynamic environment...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Join a team that's redefining partnerships in the automotive SaaS space. Lead strategic initiatives to enhance our developer ecosystem, drive commercial negotiations, and foster innovation across key...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Consumer Technology

$110K - $130K *

Champion business growth by driving market development in healthcare. Build relationships, achieve sales objectives, and influence cross-functional teams to deliver customer-centric solutions while ma...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Unlock potential by providing strategic financial insights and analysis to drive decision-making and operational efficiency. Collaborate with stakeholders to enhance profitability through budgeting, f...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.