Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$110K - $130K *

Join a dynamic team to evaluate strategic investments and growth opportunities in healthcare. Leverage market insights and financial modeling to shape multi-year business strategies, collaborating acr...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $92K *

Empower our channel partner division by managing operational activities, coordinating RFPs, and driving cross-functional collaboration to enhance sales and partner engagement. Your insights will shape...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$107K - $188K *

Unlock potential by managing high-profile accounts and driving sales growth through strategic planning and complex negotiations. Leverage your expertise to develop tailored solutions and exceed revenu...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$125K - $150K *

Join a team that's redefining global events management by leading a dynamic program management function. Oversee flagship conferences and regional events, ensuring strategic alignment, operational exc...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$180K - $220K *

Empower the revenue team by leading GTM strategy and operations, driving scalable processes and frameworks to support growth from $1B to $2B+. Collaborate across Sales, Marketing, and Finance to enhan...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$100K - $130K *

Take ownership of sales within a key territory, identifying opportunities and nurturing relationships with clients to drive business growth and exceed sales goals through strategic engagement and effe...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Help us shape the future of pulmonary care by leveraging your clinical expertise to drive product development, enhance workflows, and ensure effective solutions for COPD, asthma, and other pulmonary c...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $88K *

Empower hotel owners by analyzing performance and providing tailored consultations to enhance guest satisfaction and profitability across a diverse portfolio. Collaborate with cross-functional teams t...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$144K - $200K *

Lead the charge in developing a high-performing sales team focused on public safety. Drive recruitment, coaching, and retention while ensuring team success through strategic deal management and AI int...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$100K - $130K *

Join a team that's focused on driving sales in the oil, gas, and energy sectors. You'll cultivate key customer relationships, execute strategic sales plans, and ensure brand excellence across territor...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$75K - $107K *

Lead the charge in driving revenue growth by identifying and closing new opportunities within complex commercial accounts, leveraging strategic relationships and consultative selling to achieve ambiti...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$151K - $314K *

Shape the future of global ERP delivery by leading a diverse team, executing strategic initiatives, and driving transformation across multiple regions to enhance operational efficiency and business va...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$101K - $139K *

Unlock potential by driving strategic sales initiatives, fostering client relationships, and collaborating across teams to deliver tailored solutions. Engage with customers to assess needs and enhance...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Join a team that's dedicated to transforming literacy in PreK–12 education. Drive new business and foster long-term success by building relationships with key decision-makers and delivering impactful...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $235K *

Elevate your legal career by delivering strategic counsel and effective services to Managed Services Organizations and physician practices, while managing complex legal projects and mentoring a team i...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform the accounting function by overseeing monthly closes, ensuring compliance, and managing tax processes. Collaborate with finance leadership to drive accurate reporting and support strategic p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $138K *

Optimize sales strategies and drive growth in the US Academic market by partnering with teams to deliver innovative research solutions, enhance customer relationships, and achieve sales targets while...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$201K - $251K *

Engage with Key Opinion Leaders to drive strategic marketing initiatives, leveraging clinical expertise to influence oncologists and enhance brand strategy. Collaborate cross-functionally to execute i...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $120K *

Shape your career as you take ownership of key accounts, driving sales and building relationships. Collaborate with top performers to modernize government services, while gaining invaluable experience...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $200K *

Shape the future of digital experiences by leading cross-functional initiatives that drive impactful business outcomes through data analysis, customer insights, and strategic alignment across teams...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$76K - $142K *

Lead advanced accounting functions, ensuring compliance with GAAP and SAP. Prepare complex financial reports and analyses while collaborating with auditors. Drive financial accuracy and support manage...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Advance the administration of Defined Benefit and Retiree Medical plans, ensuring accurate valuations, benefit calculations, and compliance with regulations. Collaborate on special projects while leve...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$119K - $221K *

Advance your career by driving strategic sales initiatives within large enterprises. Collaborate with cross-functional teams to exceed sales quotas and develop innovative solutions that meet client ne...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Pioneer a data-driven future by leading product strategy for data science solutions. Drive innovation, oversee development, and ensure alignment with business goals to deliver impactful analytics prod...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.