Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$95K - $115K *

Transform channel marketing strategies by building innovative programs that drive growth in industrial and automotive sectors. Collaborate with sales leadership to navigate ambiguity and create impact...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$135K - $151K *

Drive product strategy and execution for Patient Experience solutions, enhancing healthcare practices' connection with patients. Lead cross-functional teams, leverage AI, and optimize workflows to imp...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$68K - $126K *

Transform medical billing operations by leading a team to optimize systems, enhance service delivery, and drive continuous improvement through technology and structured practices, ensuring accountabil...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive capital project execution and engineering improvements in a manufacturing facility. Lead projects from concept to completion, ensuring adherence to safety, quality, budget, and schedule while en...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Unlock your potential by driving customer success and strategic growth. Collaborate with cross-functional teams to enhance customer outcomes, mitigate risks, and expand enterprise accounts, ensuring l...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Drive sales performance by managing comprehensive compensation strategies that align with company goals. Collaborate across teams to design and implement effective plans, analyze data trends, and ensu...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Staffing

$150K - $180K *

Lead the charge in driving sales growth and market leadership for Digital Plant solutions. Collaborate with teams to develop strategies, manage key accounts, and ensure high-quality project delivery w...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$75K - $140K *

Engage with Midsize Law Firms to drive sales growth by prospecting, setting appointments, and supporting existing clients. This role offers a pathway to a full-time sales position with territory owner...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$250K - $300K *

Join a team that's redefining additive manufacturing by driving automated CAD-to-print workflows. Lead a multidisciplinary group to enhance production systems, ensuring quality and efficiency in aeros...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$250K - $300K *

Empower the future of AI in commerce media by leading strategy and execution across AI Labs and Data Science. Drive customer engagement, scale capabilities, and enhance product impact while building a...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $200K *

Drive strategic partnerships and optimize alliances to enhance revenue growth. Lead co-sell initiatives and ensure seamless partner engagement, leveraging data insights to maximize impact in AI and cl...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $155K *

Elevate product initiatives within the casino vertical by driving discovery, stakeholder engagement, and roadmap management. Collaborate with cross-functional teams to enhance player experience and en...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$168K - $253K *

Lead commercial growth in the datacenter market by driving strategy, securing design wins, and developing a high-performing sales team focused on hyperscale operators and critical infrastructure partn...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Accelerate your career by leading innovative marketing strategies that drive lead generation and revenue growth. Collaborate with cross-functional teams to enhance brand visibility and cultivate a cul...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$56K - $111K *

Drive success by cultivating strong relationships with clients to enhance satisfaction, retention, and sales growth. Collaborate with teams to deliver tailored solutions and insights, ensuring a seaml...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$350K - $400K *

Optimize enterprise sales growth by leading a high-performing team, refining strategies, and driving revenue. Collaborate across departments to enhance processes and ensure long-term success in a dyna...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Join us to drive product strategy and vision for finance functions, optimizing Record to Report and FP&A processes. Collaborate with cross-functional teams to enhance financial systems and ensure comp...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$85K - $103K *

As an Account Executive in-territory in Miami, you will be responsible for managing the full sales cycle, including building and managing a sales pipeline, prospecting, and closing deals. This role re...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

$144K - $200K *

Lead a dynamic team to drive sales in the public safety sector, focusing on recruitment, coaching, and performance management. Collaborate across functions to enhance team effectiveness and achieve re...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$90K - $100K *

Reimagine retirement solutions by driving sales in small to mid-sized markets. Collaborate with financial intermediaries to build relationships and achieve company objectives while managing a dynamic...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$130K - $191K *

Lead product strategy and execution by driving cross-functional teams to deliver high-quality solutions. Own the product lifecycle, prioritize impactful features, and leverage customer insights to ali...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$130K - $195K *

Transform enterprise sales by engaging CIOs and CTOs, leading complex sales cycles, and connecting technology strategies to measurable business outcomes. Collaborate with cross-functional teams to dri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $120K *

Lead the charge in enhancing safety standards across multiple construction projects. Collaborate with field teams to ensure compliance and improve practices, making safety a priority and fostering a c...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $140K *

Accelerate progress at driving sales execution and client relationships across commercial accounts. Lead solution-specific cycles, collaborate with experts, and achieve growth objectives while deliver...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $114K *

Transform the Value-Added Reseller ecosystem by leveraging channel expertise to drive growth, engaging partners, and developing robust strategies for customer acquisition and revenue expansion within...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.