Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$100K - $120K *

Deliver impactful sales growth by driving SaaS solutions in hospital pharmacy markets. Collaborate with various teams, engage with senior executives, and achieve targets through strategic selling and...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's transforming healthcare by driving sales of innovative water purification systems. Leverage your expertise to build relationships and ensure compliance, enhancing patient safety acr...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$63K - $120K *

Drive revenue growth by managing high-volume sales interactions, building client relationships, and executing precise strategies to exceed performance metrics. Thrive in a fast-paced environment while...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Transportation

$160K - $235K *

Lead the charge in securing K-12 district accounts, driving full-cycle sales from prospecting to closing. Engage with district leaders, navigate procurement processes, and maintain a robust pipeline a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$220K - $275K *

Partner with us to drive AI transformation in customer experience. As a Principal Solutions Engineer, you'll guide clients through the design and implementation of innovative AI solutions, ensuring al...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Join a team that's dedicated to empowering clients and mentoring new sales talent. Leverage your extensive sales experience to build relationships, implement proven processes, and guide others while m...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$105K - $120K *

Drive strategic people initiatives as a trusted advisor, shaping talent strategies and leading change. Collaborate with leaders to enhance engagement, manage complex employee relations, and mentor HR...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$102K - $170K *

Lead strategic initiatives and operational excellence as a key partner to the VP/GM, driving accountability and cross-functional coordination to enhance business performance and accelerate growth acro...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Empower the R&D organization by leading technology strategy, engineering execution, and team development across a diverse healthcare software portfolio, ensuring alignment with market needs and operat...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$160K - $220K *

Champion safety and environmental excellence by leading EHS strategies across manufacturing operations, ensuring compliance, reducing risks, and fostering a proactive culture of safety and sustainabil...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$104K - $149K *

Accelerate product development by defining, designing, and prototyping features for payment platforms across multiple ecosystems, leveraging technical expertise and AI tools to enhance user experience...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$135K - $160K *

Pioneer a transformative deal desk to empower Sales with streamlined processes, enabling faster, defensible deal-making while collaborating closely with cross-functional teams to enhance pricing strat...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$199K - $370K *

Optimize your sales expertise by driving revenue in state government sectors. Leverage your knowledge of procurement processes to build relationships and close deals, while collaborating with a top-ti...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Media

$160K - $200K *

Elevate the technical architecture vision and execution across a product portfolio, driving the transition to a scalable, cloud-native SaaS environment while integrating AI, data, and security. Collab...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$120K - $140K *

Drive growth in Level Measurement Solutions by forging relationships, managing sales channels, and capturing industry opportunities. Collaborate with teams to enhance product awareness and optimize cu...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$79K - $117K *

Grow your career with a dynamic sales role focused on building strong partnerships with distributors and end-users in the industrial sector, driving sales growth and enhancing customer relationships a...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$79K - $117K *

Join a team that's driving sales success in the North-East market by cultivating strong partnerships with distributors and end-users, leveraging value selling techniques to exceed goals and enhance cu...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Grow your career with a dynamic team dedicated to providing advanced water treatment solutions. Leverage your technical sales expertise and relationship-building skills to drive revenue and foster str...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $140K *

Transform your career by managing employee benefits for diverse clients. Collaborate with Producers and Executives to deliver exceptional service, analyze plans, and drive compliance while fostering s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $110K *

Shape your career by empowering sales teams with innovative enablement strategies. Collaborate across departments to enhance seller performance, drive revenue growth, and leverage AI tools for impactf...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$132K - $165K *

Shape the future of billing and collections by driving product strategy and enhancing user experiences. Collaborate with cross-functional teams to deliver reliable payment solutions that boost revenue...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$90K - $110K *

Empower your career by bridging technical solutions and customer needs in the drive-thru technology space. Collaborate with Sales and Product teams to design and deliver innovative solutions that enha...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $160K *

Drive the advancement of high-value, complex deals, partnering with C-Suite executives to create innovative solutions that expand the organization's portfolio and enhance strategic account growth...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Empower strategic financial decisions by analyzing investments, market opportunities, and capital allocation. Collaborate with C-suite executives to drive growth and optimize resource allocation while...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Champion operational excellence at a high-volume distribution center, leading multi-shift teams in fulfillment, inventory management, and automation initiatives while driving continuous improvement an...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.