Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$150K - $200K *

Drive impactful marketing strategies in the Healthcare sector, enhancing positioning and messaging. Collaborate cross-functionally to accelerate growth and establish thought leadership, ensuring relev...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $185K *

Shape the future of digital shelf strategy across major retailers, driving content effectiveness and retail media efficiency. Lead a high-performing team to innovate and enhance client offerings, ensu...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Media

$190K - $250K *

Launch a transformative Revenue Operations function to drive growth, partnering with leadership to design analytics, forecasting, and operational strategies that enhance performance across sales, mark...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Empower partner success by managing relationships, enhancing product adoption, and driving engagement. Collaborate with cross-functional teams to deliver exceptional service and support, ensuring part...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$170K - $200K *

Unlock potential by leading strategic finance initiatives, enhancing planning, forecasting, and reporting processes. Collaborate with executives to drive operational excellence and scale the finance f...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Transform customer success by leading a high-performing team to drive value, retention, and growth across enterprise accounts. Collaborate cross-functionally to ensure operational excellence and measu...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Advance healthcare solutions by building executive relationships and driving enterprise sales. Lead the sales lifecycle, develop strategic accounts, and leverage modern tools to optimize revenue growt...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$285K - $335K *

Lead the charge in developing and executing commercial strategies that drive brand growth and enhance decision-making capabilities across a dynamic portfolio, focusing on oncology and market insights...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$196K - $353K *

Join us to lead the West Region Oncology Sales team, driving strategy and execution for a groundbreaking mRNA therapy. Collaborate with partners, build relationships, and ensure launch excellence whil...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Optimize sales strategies to drive growth across diverse industries, leveraging your expertise in B2B sales and customer engagement. Collaborate with teams to enhance market presence and deliver tailo...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$340K *

Elevate your career by driving strategic sales in the TOLA region. Collaborate with cross-functional teams to build relationships, uncover opportunities, and deliver value through innovative SaaS solu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform your career by leading a dynamic team in commercial underwriting, driving profitable results through strategic management and development. Engage with agency partners and enhance business pr...

1 month ago

  •   8 - 10 years exp.  •   Finance & Insurance

$162K - $225K *

Join a team that's shaping the future of fintech through M&A, fundraising, and strategic projects. Collaborate with executives to drive impactful decisions and build corporate development capabilities...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$109K - $128K *

Empower industries by bridging cutting-edge IoT technology with operational excellence. Collaborate across teams to drive customer success while enhancing logistics, safety, and sustainability through...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$87K - $109K *

Transform public-sector auction services by building relationships with key decision-makers. Drive business growth through strategic outreach, presentations, and consultative selling, ensuring long-te...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$400K - $500K *

Innovate operational excellence by leading global delivery strategies, enhancing client outcomes, and driving profitability. Collaborate with executive teams to shape a scalable, AI-enabled organizati...

United StatesRemote

Today

  •   15+ years exp.  •   Enterprise Technology

$160K - $220K *

Engage with higher education institutions to foster relationships, drive customer success, and expand platform adoption. Balance strategic management and revenue growth in a dynamic environment, ensur...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Elevate customer engagement by leading SaaS renewal strategies, fostering relationships, and driving growth through negotiation and operational excellence in a dynamic environment...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$82K - $131K *

Join a team that's driving sales success in the retail sector! Manage a dynamic territory, develop strategic sales campaigns, and build lasting relationships with enterprise customers while leveraging...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive sales success by engaging with SLED accounts, implementing strategic plans, and fostering executive relationships to achieve quarterly goals and promote industry leadership in Unified Threat Man...

Des Moines, IARemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Advance your career by driving market intelligence and product strategy for RUO oncology and transplant products. Collaborate with cross-functional teams to enhance customer relationships and ensure s...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $120K *

Empower healthcare professionals by engaging remotely with cardiologists, nephrologists, and primary care providers. Drive sales and support efforts in open territories while delivering a consistent e...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Unlock potential by leading HR strategies across 12 manufacturing sites and a remote workforce. Drive high-volume hiring, simplify processes, and foster a proactive culture to support rapid growth and...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$145K - $175K *

Join a team that's redefining legal operations in a fast-paced healthtech environment. As a key player, you'll manage complex contracts, drive compliance, and leverage technology to enhance efficiency...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Elevate your career by leading a dynamic BDR team, driving pipeline generation, and optimizing sales processes. Collaborate with marketing and sales to enhance engagement strategies while fostering ta...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.