Explore Senior Machine Learning Engineer opportunities at companies building intelligent products and data-driven systems. These experienced professionals design, develop, and deploy machine learning solutions, turning research and business needs into reliable applications. Ladders features vetted professional jobs paying $100,000 or more, helping you find roles aligned with your skills and career goals.
Senior Machine Learning Engineers typically own substantial parts of the machine learning lifecycle, from defining problems and preparing data to training models, deploying services, and monitoring performance. They collaborate with data scientists, software engineers, product teams, and business stakeholders to deliver solutions that are accurate, scalable, maintainable, and useful.
Employers often seek strong programming skills, especially in Python, along with experience in machine learning frameworks, statistical methods, and software engineering practices. Familiarity with cloud platforms, distributed computing, MLOps, model evaluation, and production deployment can be valuable. Senior roles may also call for technical leadership, mentoring, and the ability to explain complex findings to cross-functional teams.
Senior Machine Learning Engineers work across industries such as technology, finance, healthcare, retail, and logistics. Depending on the organization, the role may focus on generative AI, recommendation systems, search, computer vision, natural language processing, forecasting, or fraud detection. Experienced engineers can grow into staff or principal engineering roles, technical management, or specialized AI leadership positions.
Search Senior Machine Learning Engineer jobs on Ladders to discover vetted professional opportunities with salaries of $100,000 or more. Compare roles by responsibilities, required expertise, and growth potential, then identify openings that match your experience in building and operating machine learning systems.
Principal Machine Learning Engineer, Signals and Measurement
$276K - $414K *
Innovate advanced machine learning systems that support monetization strategies, collaborating across teams and driving best practices to enhance performance, availability, and scalability while influ...
4 weeks ago
$110K - $160K *
Elevate your career by owning and evolving a robust data platform. Design scalable infrastructure, build reliable pipelines, and create a foundation for AI applications, ensuring data quality and acce...
Reposted 3 weeks ago
$125K - $205K *
Transform our data ecosystem by designing and evolving scalable infrastructure, ensuring reliable data movement, and building a robust foundation for AI applications. Collaborate with teams to enhance...
Reposted 3 weeks ago
Staff Software Engineer, Capacity Engineering
$170K - $277K *
Lead the development of systems and tools for infrastructure capacity planning and efficiency. Collaborate with cross-functional teams to optimize resource allocation and drive measurable savings whil...
4 days ago
$125K - $150K *
Lead the charge in transforming innovative ideas into impactful AI-driven solutions for public health and medical research. Collaborate with diverse teams to develop MVPs that enhance scientific disco...
5 days ago
$150K - $180K *
Shape the future of automated workflows by building reliable LLM-based systems. Collaborate with a core product team to deliver innovative solutions across regulated domains, ensuring safety and perfo...
5 days ago
$120K - $214K *
Transform your career by developing AI solutions that enhance platform reliability and developer workflows. Collaborate with cross-functional teams to build scalable, secure, and responsible AI system...
4 days ago
Machine Learning Engineer Graduate - Global E-commerce Recommendation/Search - 2026 Start (PhD)
$162K - $316K *
Engage in cutting-edge research on machine learning algorithms for e-commerce, focusing on enhancing user experiences through personalized recommendations and risk control technologies. Collaborate on...
Reposted 2 days ago
Machine Learning Engineer Graduate - Global E-commerce Recommendation/Search - 2026 Start (PhD)
$153K - $300K *
Empower innovation as you collaborate in machine learning research and e-commerce systems, harnessing algorithms for user engagement and security. Join us for a transformative journey in tech and expl...
Reposted 3 weeks ago
$150K - $180K *
Engineer the future of API products by building scalable platforms for model integration, enabling seamless data ingestion, fine-tuning, and low-latency inference for diverse partners, from hobbyists...
3 weeks ago
Senior Data Engineer, Bioinformatics, Cheminformatics, Materials
$144K - $240K *
Optimize scientific data platforms by creating efficient ETL pipelines and reliable datasets. Collaborate with researchers to transform raw outputs into structured data, enhancing analysis and workflo...
Reposted 1 week ago
Machine Learning Engineer 4 (Manager, IC)
$197K - $225K *
Drive innovation in AI by designing and deploying machine learning models. Collaborate with cross-functional teams to solve complex business challenges and optimize production systems, ensuring best p...
3 weeks ago
Machine Learning Engineer 4 (Manager, IC)
$215K - $245K *
Pioneer innovative AI solutions by designing and deploying ML models. Collaborate with cross-functional teams to tackle complex business challenges and optimize production systems, ensuring best pract...
3 weeks ago
Machine Learning Engineer 4 (Manager, IC)
$197K - $225K *
Champion innovative machine learning solutions by designing, building, and deploying models that address complex business challenges. Collaborate with cross-functional teams to enhance AI capabilities...
3 weeks ago
Machine Learning Engineer 4 (Manager, IC)
$215K - $245K *
Empower innovation by designing and deploying advanced machine learning models. Collaborate with cross-functional teams to solve complex business challenges and drive AI transformations in a fast-pace...
3 weeks ago
$120K - $145K *
Drive innovation in insurance technology by transforming Gosu customizations into Java. Collaborate with cross-functional teams to design scalable backend services and APIs, enhancing the Guidewire Cl...
2 weeks ago
Senior Machine Learning Manager, TikTok Trust and Safety
$308K - $500K+*
Innovate advanced machine learning solutions for content moderation, safeguarding billions of users daily. Lead design and implementation of predictive models, collaborating cross-functionally to enha...
Reposted 1 week ago
Data Scientist II, Product - Moloco Commerce Media
$148K - $180K *
Shape product success by leveraging data insights, driving experimental methodologies, and collaborating across teams to influence decision-making in a fast-paced, innovative environment...
Reposted 3 weeks ago
$140K - $180K *
Lead and innovate data science initiatives across multiple centers, establishing standards for AI adoption and analytics. Mentor a team of professionals while guiding the deployment of analytical tool...
1 month ago
Senior Security Application Engineer - Automation & Detection
$130K - $155K *
Transform security operations by defining detection strategies, enhancing product security, and integrating cryptographic governance. Collaborate across teams to build automated solutions and lead tec...
2 weeks ago
$179K - $204K *
Transform the future of AI by designing and deploying cutting-edge machine learning models. Collaborate with cross-functional teams to solve complex business challenges and optimize production systems...
2 days ago
$179K - $204K *
Lead the charge in developing innovative machine learning solutions that drive AI transformations. Collaborate with cross-functional teams to design, build, and deploy scalable models, ensuring best p...
2 days ago
$215K - $245K *
Join us to drive AI transformations by designing and deploying machine learning models. Collaborate with cross-functional teams to solve complex business challenges and optimize data pipelines in a fa...
2 days ago
$179K - $204K *
Pioneer innovative AI solutions by designing and deploying machine learning models. Collaborate with cross-functional teams to tackle complex business challenges and drive impactful transformations in...
2 days ago
$197K - $225K *
Grow your career with a dynamic team driving AI transformations and scaling ML models. Collaborate across disciplines to solve complex business challenges using cutting-edge technologies in a fast-pac...
2 days ago
What does a Senior Machine Learning Engineer do?
A Senior Machine Learning Engineer builds and operates machine learning systems, including preparing data, developing and evaluating models, deploying them into production, and monitoring their performance. They often guide technical decisions and collaborate with product, data, and engineering teams.
What qualifications are commonly required for Senior Machine Learning Engineer jobs?
Requirements vary, but commonly include strong programming ability, machine learning and statistical knowledge, experience with production software, and familiarity with tools or frameworks used to train and deploy models. Senior positions may also require cloud, MLOps, system design, and mentorship experience.
What industries hire Senior Machine Learning Engineers?
Technology, finance, healthcare, retail, logistics, and many other sectors hire Senior Machine Learning Engineers to develop applications such as recommendations, fraud detection, forecasting, language technologies, and computer vision.
How can I find Senior Machine Learning Engineer jobs paying $100,000 or more?
Use Ladders to explore vetted professional openings with salaries of $100,000 or more. Review each listing's responsibilities, qualifications, and compensation details to find roles that fit your background and goals.