Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$125K - $150K *

Champion the technical integration of partner ecosystems, ensuring seamless onboarding and operational reliability. Drive API discovery, documentation, and troubleshooting while collaborating with int...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$113K - $188K *

Optimize security administration and reporting processes while collaborating with cross-functional teams to enhance data insights and compliance metrics. Drive effective use of Workday tools and ensur...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Lead the charge in program management excellence, ensuring seamless operations and compliance across diverse teams while supporting critical Air Force contract initiatives and rapid-response readiness...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$170K - $230K *

Drive strategic growth and innovation in AI-enabled assessment and workforce solutions. Lead high-impact projects, foster collaboration, and enhance AIR's national leadership in education and workforc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to driving financial excellence through detailed analysis, reporting, and strategic recommendations. Collaborate with leadership to enhance financial performance and suppo...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $121K *

Champion community college initiatives by leading project management, collaborating with stakeholders, and driving educational reforms to enhance student success and program quality across Iowa's comm...

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$94K - $164K *

Drive business continuity and disaster recovery initiatives, ensuring critical operations are sustained and services restored post-disruption. Collaborate with stakeholders to assess risks, validate r...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $152K *

Transform executive support by leading a dynamic team of EAs, enhancing processes, and driving strategic initiatives that align with company goals while fostering a collaborative culture...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $106K *

Transform your career by partnering with us to enhance investment operations. As a key player, you'll manage private credit transactions, ensuring accurate accounting and reporting while driving proce...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Join us to drive impactful data analysis that enhances product performance and operational effectiveness. Collaborate with cross-functional teams to uncover insights, develop KPIs, and translate compl...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in developing client relationships and driving new business opportunities in the Life Sciences sector. Utilize a consultative sales approach to create bespoke marketing campaigns and m...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K *

Join a team that's driving impactful cross-functional initiatives by leading strategic delivery efforts. Leverage your project management expertise to align complex projects with enterprise priorities...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Engage in the design and management of enterprise endpoint technologies, ensuring security and efficiency across over 1,000 devices. Collaborate with cross-functional teams to enhance endpoint perform...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Elevate your project management career by leading a strategic platform within investor client coverage, enhancing client engagement and driving technology integration across CBRE's commercial real est...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$125K - $157K *

Shape the future of commercial banking by leading strategic implementations, optimizing client operations, and advising on best practices to enhance financial institution capabilities and drive long-t...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in overseeing a national Audit & Compliance team, ensuring regulatory adherence, risk management, and operational excellence while driving process improvements and fostering cross-func...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$200K - $225K *

Transform healthcare data into actionable insights by leading actuarial strategy and health economic analyses. Collaborate with cross-functional teams to enhance value propositions and drive commercia...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$74K - $91K *

Join our team to investigate healthcare fraud, waste, and abuse through data analysis. Utilize your expertise in Excel and communication skills to analyze cases, conduct interviews, and support legal...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$145K - $175K *

Champion EPAM's growth by leading Advisor Relations strategy across North America. Build trusted relationships with sourcing advisors to drive commercial opportunities and enhance market perception, a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$210K - $258K *

Unlock your potential as a Senior Engagement Manager, leading complex consulting projects for pharmaceutical clients. Drive strategic medical initiatives, foster client relationships, and mentor teams...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$270K - $340K *

Unlock potential by driving sales for innovative healthcare compliance solutions. Own the full sales cycle with health plans, transforming initial conversations into lasting partnerships while shaping...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Shape the future of integrated marketing strategies by owning the creative process from ideation to execution. Collaborate with teams to deliver impactful campaigns that drive performance and renewals...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Media

$98K - $163K *

Drive your career forward by transforming financial management processes, enhancing operational efficiency, and collaborating with senior stakeholders to implement innovative solutions in a dynamic co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Champion strategic technology solutions for back-office operations, translating complex business needs into actionable plans. Collaborate with stakeholders to enhance ERP systems, improve processes, a...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$155K - $165K *

Shape the future of retail by driving sales and operational excellence across a high-volume district. Lead and develop Store Managers, ensuring brand consistency and delivering exceptional customer ex...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.