Grasp unique opportunities in the scientific realm by exploring high-paying Principal Scientist jobs that offer annual remuneration of over $100,000. Broaden your professional horizons and get closer to your career goals with our advanced search tools for Principal Scientists.
As a Principal Scientist, you will lead innovation, drive scientific research, and contribute to the growth of the scientific community at large. It is a role that combines leadership, in-depth scientific knowledge, and impactful decision-making.
We provide comprehensive job listings, insightful articles, growth opportunities, and a diverse range of resources for Principal Scientists looking to make their next career move.
Principal Scientist, CMC Analytical
$150K - $190K *
Unlock potential by leading analytical strategies for drug development, ensuring robust quality control throughout product lifecycle. Collaborate with partners to deliver exceptional insights that dri...
Today
Principal Scientist Algorithm Lead
$151K - $261K *
Elevate NGS diagnostic innovation by leading algorithm development to enhance clinical outcomes. Drive analytical validation, regulatory readiness, and algorithm performance in oncology, focusing on s...
6 days ago
Senior Principal Scientist, Drug Substance
$175K - $230K *
Elevate drug substance development by leading process innovation and CDMO partnerships. Drive projects from early development through commercialization, ensuring regulatory compliance and strategic al...
2 weeks ago
Senior Principal, AI Product Owner - Agentic AI
$175K - $230K *
Lead the charge in shaping AI products for a resilient global supply chain. Drive strategies, governance, and scalable AI delivery while partnering across teams to enhance data readiness and operation...
5 days ago
Senior Principal, AI Product Owner - LLMs
$175K - $230K *
Lead the strategy and implementation of AI-driven products leveraging large language models to enhance supply chain efficiency. Collaborate with cross-functional teams to ensure data readiness and dri...
5 days ago
Director, Scientific Solutions
$130K - $180K *
Join us as a key leader in driving the commercial strategy for scientific solutions while developing a high-performance team that engages top-tier clients in the life sciences sector. Own flagship acc...
Yesterday
$125K - $224K *
Contribute to groundbreaking research by enhancing atmospheric radiative transfer models, collaborating with a team of experts, and driving innovation in numerical methods within the scientific commun...
2 weeks ago
Scientific Product Solutions Lead
$100K - $130K *
Innovate in the development of AI-powered scientific solutions, collaborating with cross-functional teams to design, configure, and implement systems that enhance scientific workflows and data managem...
Yesterday
Principal Scientist, Translational Oncology - Single Cell and Spatial Genomics, Solid Tumors
$171K - $214K *
Join a pioneering oncology research team to lead translational projects, integrating cutting-edge single-cell and spatial biology technologies to enhance drug discovery and clinical applications acros...
1 week ago
Senior Principal, AI Product Owner - Machine Learning
$175K - $230K *
Drive your career with innovative AI and machine learning products that enhance global supply chain efficiency. Own strategy, elevate data standards, lead governance, and foster collaboration in a sen...
3 days ago
$120K - $150K *
Transform the future of drug development by leading innovative simulation projects, acting as a scientific liaison between clients and teams, and driving advances in pharmacometrics with your expertis...
3 days ago
$100K - $130K *
Accelerate progress at the forefront of clinical research by designing and conducting studies that enhance our understanding of new therapies, while collaborating with multidisciplinary teams and appl...
2 weeks ago
Senior Clinical Scientist, ECD
$142K - $178K *
Lead the charge in clinical development for early cancer detection by driving study execution, data review, and strategic insight. Collaborate with cross-functional teams to enhance clinical strategy...
2 days ago
$120K - $135K *
Advance your career by leading complex AI and IT projects. This high-visibility role entails managing cross-functional teams and driving accountability across multiple workstreams, ensuring successful...
2 weeks ago
$130K - $180K *
Shape innovative AI/ML initiatives to enhance student engagement and retention. Lead cross-functional teams to develop predictive models and data pipelines, driving measurable outcomes for thousands o...
Today
Director, PF Project Delivery - Project Farma
$150K - $170K *
Accelerate progress at leading innovative projects while driving business growth and team success through strategic leadership, client engagement, and operational excellence in the biomanufacturing se...
Reposted 2 weeks ago
Senior Manager, Marketing Program Management
$135K - $190K *
Join a team that's shaping the future of marketing through innovative program management, leading strategic campaigns, and leveraging AI tools for enhanced productivity and effectiveness in a dynamic...
Today
$165K - $206K *
Lead the charge in transforming complex data into actionable insights, partnering with stakeholders to measure and optimize commercial strategies, and architecting large datasets to influence critical...
1 month ago
Senior Principal Architect, AI
$173K - $277K *
Innovate within the AI Center of Excellence to architect and govern advanced AI solutions, shaping how AI is designed, deployed, and scaled across all engineering projects with a commitment to excelle...
5 days ago
$152K - $190K *
Join a team that's shaping the future of healthcare through innovative software solutions. As a technical leader, you'll drive the design and development of next-gen clinical data platforms while ment...
Reposted 1 week ago
Senior Director of Program Management, Global Operations
$150K - $180K *
Lead impactful client engagements by managing complex drug substance and product development programs. Drive success through cross-functional teamwork, strategic oversight, and proactive client relati...
Reposted 3 weeks ago
Research Scientist, Virtual Cell Modelling & Perturbative Biology Foundation Models
$120K - $150K *
Join us to drive innovations in drug discovery through advanced ML techniques, focusing on predictive modeling in cellular responses. Collaborate with a diverse team to turn complex data into actionab...
Yesterday
Senior Research Scientist, Evidence Synthesis
$90K - $120K *
Lead innovative projects in evidence synthesis as a Senior Research Scientist, collaborating across multiple teams to develop client-ready deliverables and oversee systematic reviews while mentoring j...
Yesterday
$90K - $120K *
Advance pharmaceutical marketing analytics by leading insight delivery and measurement strategies. Oversee KPI frameworks, reporting processes, and data visualization to ensure compelling insights tha...
6 days ago
$100K - $130K *
Join a team that's leading innovative Cost Improvement Projects in medical devices. You'll manage engineering efforts, ensuring compliance while driving change and collaboration across cross-functiona...
3 weeks ago
What is the role of a Principal Scientist?
A Principal Scientist typically leads scientific research, explores innovative ideas, and guides a team of scientists towards achieving the organization's scientific goals.
How much does a Principal Scientist earn on average?
The average salary of a Principal Scientist varies depending on the industry and level of experience. However, on Ladders, you can find Principal Scientists jobs that pay over $100,000.
What qualifications are required for Principal Scientist jobs?
Most Principal Scientist roles require at least a Ph.D. in a relevant scientific field along with several years of research experience. Leadership skills and a proven research track record are typically also essential.
Can I find remote Principal Scientist jobs on Ladders?
Yes, on Ladders, you can find both remote and in-office high-paying Principal Scientist jobs.