Explore High-Paying Jobs in Pennsylvania

Discover professional opportunities across Pennsylvania with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From major business centers like Philadelphia and Pittsburgh to growing communities throughout the state, Pennsylvania offers opportunities for experienced professionals across a range of industries.

Find Opportunities Across Pennsylvania

Search for roles in Pennsylvania’s largest cities and regional hubs. Whether you’re considering a move to Philadelphia, Pittsburgh, Harrisburg, or another location, you can browse openings and compare opportunities by job title, location, and other relevant criteria.

Explore Industries and Career Paths

Pennsylvania’s economy spans sectors such as healthcare, financial services, technology, manufacturing, education, and energy. The roles available vary by employer and location, so use search filters to focus on positions that align with your expertise, career goals, and preferred work arrangement.

Search Vetted Jobs Paying $100K+

Ladders focuses on professional jobs with salaries of $100,000 or more. Review listings for details about responsibilities, qualifications, compensation, and location, then apply directly to opportunities that match your experience.

Take the Next Step in Your Pennsylvania Job Search

Browse Pennsylvania job listings to find your next career opportunity. Narrow your search by city, function, or seniority to identify roles suited to your background and ambitions.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,459

Sort By: Relevance

$96K - $151K *

Engineer strategic supplier management initiatives to enhance supply chain resilience, drive cost improvements, and support product development. Collaborate across teams to ensure effective sourcing s...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$142K - $224K *

Optimize sales incentive strategies by leading execution and governance processes. Collaborate cross-functionally to ensure timely, compliant payouts while managing vendor relationships and anticipati...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Advance your career by leading a dedicated team in delivering trauma-informed care for substance use disorders. Shape clinical practices and foster a supportive environment in a new clinic focused on...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Lead the charge in driving wholesale growth by collaborating with cross-functional teams to develop strategic product assortments, optimize inventory, and maximize sales performance throughout the sea...

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$164K - $225K *

Develop and execute patient advocacy strategies, engaging with PAOs and cross-functional teams to elevate the patient voice and ensure successful partnerships for rare disease therapeutic areas...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$79K - $119K *

Transform patient care by providing essential after-hours nursing support, assessing conditions, and coordinating with interdisciplinary teams to ensure quality outcomes and continuity of care for hos...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Optimize strategic opportunities by leading cross-functional initiatives and applying AI-driven solutions to enhance business performance, while collaborating with senior leaders to drive impactful ch...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$107K - $171K *

Shape the market narrative for AI Agent Identity by leading product marketing initiatives. Own positioning, messaging, and commercial enablement for DNSid, translating complex innovations into compell...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$137K - $219K *

Elevate IT operations by orchestrating complex initiatives, driving user adoption, and optimizing delivery processes. Serve as the key liaison among technical teams and business stakeholders to ensure...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$138K - $163K *

Drive the evolution of software solutions for healthcare quality reporting, leading engineering teams to deliver innovative, high-quality products while fostering a culture of collaboration and contin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$141K - $278K *

Transform supply chain networks by leading strategic design and optimization initiatives. Engage with clients to enhance operational efficiency and drive value through innovative solutions and advance...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$141K - $278K *

Transform supply chain networks by leading strategic design and optimization initiatives. Drive efficiency and responsiveness through innovative solutions, guiding teams and clients from planning to e...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Empower innovation by leading design for core AI surfaces, shaping strategy and vision. Collaborate with cross-functional teams to define user experiences and establish quality standards for AI-genera...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Shape the future of overhead transmission projects by developing precise cost estimates for 69kV to 765kV construction. Collaborate with engineering and operations teams to ensure competitive and comp...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $200K *

Lead client engagements by leveraging tax expertise to drive revenue growth, manage complex planning discussions, and enhance client relationships while ensuring strategic alignment across teams for o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $200K *

Lead a dynamic team of Equipment Sales Specialists to drive sales growth, enhance customer satisfaction, and innovate equipment offerings in the dental sector while collaborating with cross-functional...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Manage and optimize public-sector transportation and facility projects from planning through closeout, ensuring effective delivery, budget adherence, and client satisfaction while collaborating with m...

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$95K - $115K *

Unlock potential by leading public-sector transportation projects from planning to closeout. Collaborate with clients and teams to ensure successful project delivery, managing scope, budget, and sched...

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$79K - $102K *

Champion customer success by guiding Mid-Market clients through the deployment and adoption of IoT solutions, ensuring they maximize value from our technology while building strong relationships acros...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Drive strategic insights by analyzing cross-functional data to enhance decision-making. Collaborate with teams to build a trusted business intelligence framework, delivering actionable recommendations...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Unlock the potential of seamless data exchange by analyzing EDI requirements, developing maps, and supporting integrations. Collaborate with partners to ensure efficient transactions and enhance elect...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's focused on driving growth in Healthcare and Financial Services. Leverage your enterprise sales expertise to build relationships, develop new business, and deliver impactful technolo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$87K - $114K *

Lead the charge in fraud prevention by analyzing data, assessing risks, and collaborating with teams to enhance fraud protection strategies across the organization. Drive impactful change through exec...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$83K - $116K *

Partner with us to drive business development in home improvement financing, fostering relationships with contractors and sponsors. Leverage your expertise to identify opportunities, enhance CRM proce...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$70K - $96K *

Accelerate growth by building relationships with healthcare providers, driving product adoption, and supporting innovative technologies that enhance patient care in a rapidly expanding healthcare land...

Washington, PARemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of high-paying jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior and professional roles across fields such as healthcare, finance, technology, manufacturing, education, and energy. Available positions vary by employer and location.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, and other cities and communities across the state. Browse current listings to see where employers are hiring.

  • Do Pennsylvania jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for its compensation details and any applicable salary range.

  • How can I narrow my search for jobs in Pennsylvania?question toggle

    Use search filters such as location, job title, industry, and seniority to focus on opportunities that fit your experience and preferences.

  • Are remote or hybrid jobs available in Pennsylvania?question toggle

    Some listings may offer remote or hybrid arrangements, depending on the employer and position. Review each job description for its work-location details.