Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Jobs in Pennsylvania

Average Salary in USD

Average Salary: $121,477

Sort By: Relevance

$150K - $180K *

Transform the Federal landscape by leading enterprise sales efforts, engaging with SES leaders, and driving digital transformation across major accounts. Collaborate with cross-functional teams to ach...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$73K - $98K *

Join a team that's dedicated to excellence in DRG auditing. Leverage your expertise in MS-DRG and APR-DRG coding to ensure accuracy and compliance while working remotely. Enjoy a collaborative environ...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$135K - $160K *

Join a team that's redefining application security through automation and AI. As a Senior DevSecOps Engineer, you'll enhance secure software delivery, integrate security into the SDLC, and drive vulne...

Philadelphia, PARemote

Today

  •   8 - 10 years exp.  •   Staffing

$135K - $160K *

Lead the charge in enhancing application security through automation and vulnerability management. Collaborate with cross-functional teams to integrate security into the SDLC, leveraging AI technologi...

Today

  •   8 - 10 years exp.  •   Staffing

$113K - $198K *

Champion advanced fire engineering solutions by leading design efforts, mentoring teams, and driving business development. Collaborate across disciplines to ensure project success while maintaining hi...

Today

  •   8 - 10 years exp.  •   Technical Services

$120K - $155K *

Join a team that's dedicated to nurturing and expanding client relationships in the Major Market sector. Drive revenue growth through upselling and cross-selling while ensuring long-term satisfaction...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$101K - $129K *

Join a team that's dedicated to enhancing patient safety and quality improvement initiatives. Collaborate with clinical leaders to drive impactful changes, ensuring optimal patient outcomes and foster...

Today

  •   Less than 5 years exp.  •   Healthcare

$90K *

Shape the future of business analysis by connecting program needs with technical solutions. Leverage your Salesforce expertise to enhance workflows, gather requirements, and collaborate with stakehold...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$100K - $175K *

Transform operations by leveraging your expertise in IT and cybersecurity. Collaborate with leaders to enhance processes, drive efficiency, and ensure compliance while mentoring teams and aligning str...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$230K - $322K *

Lead the development of machine learning models to enhance advertiser insights, optimizing campaign performance through advanced forecasting and scenario analysis. Collaborate across teams to drive im...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Media

$95K - $115K *

Lead the development and optimization of manufacturing processes, ensuring technical integrity and continuous improvement. Collaborate with cross-functional teams to drive sustainable solutions and en...

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$125K - $150K *

Transform business workflows by developing and maintaining applications that enhance productivity and information sharing across teams. Collaborate with IT and business units to deliver innovative sol...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Technical Services

$80K - $95K *

Pioneer branch operations by leading a dynamic team, driving sales, and ensuring project success. Oversee customer engagement, financial performance, and compliance while identifying growth opportunit...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $115K *

Unlock your potential by leading customer deployments, ensuring accurate software configuration, and providing user training. Collaborate with teams to enhance operational efficiency and drive success...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Lead strategic initiatives in Outside Plant Broadband management, optimizing product performance, pricing, and inventory. Collaborate across teams to enhance sales enablement and vendor partnerships...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$82K - $90K *

Develop your career by managing diverse properties across regions, ensuring financial performance and resident satisfaction. Collaborate with teams to enhance community engagement and uphold complianc...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Lead the charge in Quality Operations by overseeing clean room activities, ensuring compliance with GMP standards, and mentoring team members to foster a culture of excellence and continuous improveme...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $225K *

Champion the development of a GPU-accelerated compute platform, enhancing AI training and research capabilities. Collaborate with cross-functional teams to design orchestration systems that optimize r...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $195K *

Join a team that's redefining account marketing for major clients. Collaborate with cross-functional partners to drive growth, enhance customer engagement, and create tailored marketing strategies tha...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$450K - $475K *

Drive revenue growth by leading a team of Regional Directors, fostering collaboration, and ensuring alignment with company goals. Your leadership will shape the region's success and culture while enha...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$99K - $155K *

Drive impactful marketing initiatives by executing campaigns, managing operations, and collaborating with teams to enhance brand visibility and support sales growth. Leverage data insights to optimize...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$108K - $130K *

Unlock your potential by collaborating with experts to innovate software acquisition strategies for the Department of War. Drive impactful solutions and enhance modern practices in a mission-focused e...

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Join a team that's dedicated to empowering growth through strategic sales initiatives. As a key player, you'll drive results by building relationships, mentoring peers, and achieving personal and team...

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $187K *

Lead the development of innovative software solutions using Python and AWS. Collaborate with cross-functional teams to create scalable applications that leverage AI/ML technologies, ensuring high perf...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Transform the future of AI-driven infrastructure products by leading strategic growth initiatives, collaborating closely with Marketing and Engineering, and influencing key product decisions for optim...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.