Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$77K - $96K *
Grow your career with a vital role in payroll operations that ensures compliance and enhances customer experience through effective account management and issue resolution across multiple jurisdiction...
Reposted 4 weeks ago
$115K - $130K *
Engage with stakeholders to drive product strategy and enhance the Affordable Equity platform. Collaborate with teams to translate user needs into actionable solutions, ensuring timely delivery and al...
3 weeks ago
$225K - $250K *
Transform operations by leading a diverse team to enhance profitability and efficiency across multiple sites, while building strategic relationships with clients and driving growth initiatives in the...
1 week ago
$200K - $225K *
Transform marketing strategies to drive growth and engagement across public and private sectors. Lead integrated marketing efforts, brand positioning, and customer marketing services while leveraging...
3 days ago
Director, Executive Engagement
$182K - $215K *
Transform executive engagement by building strategic advisor relationships, designing impactful experiences, and leveraging industry insights to elevate pay governance as a strategic priority for clie...
2 weeks ago
Senior Product Manager (Healthcare Data Products)
$120K - $145K *
Transform healthcare data products by leading strategy, execution, and cross-functional collaboration. Drive product-market fit and commercialization for API-based solutions, ensuring alignment with c...
Today
$125K - $150K *
Lead the charge in transforming public sector consulting by guiding organizations through digital transformation and ERP implementations, while managing high-impact teams and fostering client relation...
3 weeks ago
Sr. Regional Web Product Manager
$131K - $155K *
Drive regional website strategy for multiple international markets. Collaborate cross-functionally to enhance user experience, support AEO/SEO initiatives, and manage web performance metrics. Lead exp...
Reposted 4 weeks ago
$90K - $100K *
Transform software delivery by managing cross-functional teams, aligning sprints, and optimizing project timelines. Drive clarity in processes and foster collaboration to ensure successful product exe...
Reposted 1 week ago
Manager, Government Contracts & Compliance
$80K - $95K *
Drive compliance and contract administration for federal government contracts. Collaborate with cross-functional teams to ensure adherence to regulations, manage audits, and maintain records. Shape pr...
2 days ago
$100K - $120K *
Engage in new business acquisition by identifying, qualifying, and closing sales opportunities. Build strong client relationships and deliver tailored presentations while achieving sales quotas in a d...
3 weeks ago
$110K - $130K *
Join a team that's driving financial strategy and operations, leading forecasting, reporting, and analysis to support a fast-growing organization with impactful decision-making and collaboration acros...
Reposted 4 weeks ago
$216K - $361K *
Elevate your career by driving sales growth in enterprise software across retail, energy management, and telecommunications. Collaborate with top clients to achieve strategic goals and expand market p...
Yesterday
Director, Partner Marketing (Remote)
$125K - $150K *
Lead and innovate partner marketing strategies across diverse retail segments, managing a team to drive growth and enhance relationships. Collaborate cross-functionally to develop impactful campaigns...
2 weeks ago
$150K - $251K *
Pioneer innovative technology strategies and architectural solutions across Agile teams, driving AI-enabled engineering transformation and ensuring scalable, secure, and maintainable solutions for ent...
1 week ago
Solution Engineer (Billing Specialist)
$105K - $130K *
Join a team that's redefining billing solutions in the legal sector. Leverage your expertise in law firm financial operations to support sales efforts, conduct client demos, and enhance our innovative...
3 weeks ago
Director, Health Systems Partnerships
$190K - $240K *
Elevate healthcare impact by building and scaling enterprise accounts in women's health. Own the sales cycle, engage stakeholders, and drive screening initiatives while collaborating across teams to e...
Reposted 4 weeks ago
Implementation Manager, Financial Services
$100K - $120K *
Accelerate client success by owning the onboarding and rollout for enterprise clients, ensuring smooth transitions from purchase to sustained usage. Collaborate with cross-functional teams to drive ad...
Today
Associate Director- Model Audit, Model Build and Transactions Advisory
$120K - $145K *
Drive excellence by leading model audits and mentoring a dynamic team. Collaborate on complex financial models, ensuring accuracy and strategic growth, while enhancing methodologies to deliver top-not...
Reposted today
Associate Director, Programmatic
$105K - $120K *
Join a dynamic team as you lead integrated media strategy and client relationships in programmatic advertising. Drive innovation, mentor talent, and collaborate cross-functionally to achieve strategic...
3 weeks ago
$90K - $115K *
Drive the administration of OneStream, supporting FP&A and Accounts Payable teams. Enhance reporting, manage data integrations, and collaborate with Finance and IT to optimize processes and improve ef...
2 weeks ago
Director, Threat Detection & Response
$175K - $235K *
Accelerate progress at the forefront of cybersecurity by leading incident response, detection engineering, and threat hunting teams. Drive strategy and build capabilities to protect critical payment p...
2 weeks ago
Director, Technical Product Management
$150K - $180K *
Pioneer the strategy and execution of data platforms and AI products, leading cross-functional teams to enhance commercial life sciences solutions while driving revenue growth and product adoption in...
Reposted 3 days ago
$130K - $150K *
Drive sales growth and platform adoption by executing strategic marketing initiatives, collaborating across teams, and leveraging customer insights to enhance product positioning and sales enablement...
4 weeks ago
$100K - $120K *
Engage with diverse stakeholders to drive sales initiatives, source new clients, and expand existing accounts. Leverage strong prospecting and strategic relationship-building skills in a fast-paced, c...
4 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.