Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Director, Revenue Cycle Jobs in South Dakota

Sort By: Relevance

$130K - $160K *

Transform the planning landscape by leading integrated sales and operations processes. Drive cross-functional collaboration, develop robust planning models, and ensure alignment on business objectives...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Shape the future of healthcare technology by leading clinical strategy initiatives to enhance drug diversion prevention and ensure patient privacy compliance. Drive impactful relationships, educate st...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's leading Medicaid programs and initiatives, driving operational excellence and policy implementation while managing multidisciplinary teams and enhancing organizational performance a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$180K - $225K *

Tackle the procurement lifecycle for mission-critical cooling equipment in data centers. Lead strategic initiatives, supplier performance, and operational excellence, while managing risks and driving...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$61K - $122K *

Optimize product delivery by bridging business needs and technical teams, leading requirement gathering, defining user stories, and ensuring alignment with stakeholders to enhance Epic EHR capabilitie...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$76K - $90K *

Transform compliance by managing DOT trucking programs, ensuring safety and regulatory adherence across operations. Collaborate with teams to develop effective EHS initiatives and maintain high standa...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$74K - $87K *

Unlock patient access by managing the insurance verification process, addressing barriers to care, and ensuring seamless coordination among stakeholders to facilitate timely therapy access and support...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$92K - $116K *

Lead and inspire a team of Client Service Managers to elevate client satisfaction, driving operational excellence while managing strategic service delivery and fostering strong client relationships fo...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Inspire patient recruitment strategies by leading a dynamic team, collaborating with senior management, and leveraging innovative tools to enhance enrollment across clinical trials while ensuring dive...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$223K - $313K *

Collaborate with a dedicated team of physicians to ensure high-quality inpatient care through clinical expertise, thorough reviews, and utilization management. Advance patient outcomes by utilizing st...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Engage with cross-functional teams to drive clinical trial success across regions. Leverage your expertise in project management and mentoring to ensure compliance, quality, and timely execution of st...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $94K *

Transform patient access operations by leading centralized support functions, optimizing workflows, and enhancing service quality across multiple regions. Drive continuous improvement and develop lead...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $200K *

Shape the future of international financial reporting by leading statutory and sustainability reporting for global entities, ensuring compliance and accuracy while collaborating with cross-functional...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Empower your career by managing complex cloud discount instruments. Leverage your FinOps expertise to optimize financial operations and enhance our autonomous cloud management system, ensuring seamles...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $100K *

Unlock potential by leading a dynamic team of developers to deliver high-quality software solutions, collaborating with stakeholders, and driving strategic project initiatives while fostering a cultur...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$142K - $237K *

Lead transformative initiatives in a strategic role, driving international business growth and operational excellence across regions and functions. Collaborate with senior stakeholders to implement a...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$73K - $115K *

Unlock the potential of clinical documentation integrity by driving ICD-10-CM coding accuracy and enhancing provider education. Collaborate with cross-functional teams to support risk adjustment initi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Join a dynamic team to lead and scale clinical operations, overseeing performance and process optimization. Build accountable teams, manage metrics, and partner with stakeholders to enhance operationa...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$64K - $96K *

Engage in comprehensive risk adjustment audits and compliance reviews, ensuring accurate data submission to CMS. Collaborate with coding teams and management to uphold regulatory standards and improve...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform your career as a strategic finance leader, driving financial operations and strategic planning. Own the P&L, balance sheet, and cash flow while partnering with executives to shape growth and...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$116K - $155K *

Shape the future of HR technology by leading strategy, governance, and optimization of HRIS. Drive operational excellence, enhance user experience, and ensure compliance while managing a high-performi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$191K - $238K *

Shape the future of oncology by leading medical strategy for prostate cancer projects. Collaborate with cross-functional teams to drive scientific communication and strategic initiatives, ensuring ali...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $135K *

Shape impactful training programs for Field Access teams, enhancing access and reimbursement capabilities across therapeutic areas. Collaborate with stakeholders to ensure compliance and relevance, fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Lead high-impact client delivery operations, ensuring quality execution and resource optimization across diverse projects. Collaborate with cross-functional teams to drive performance and enhance cust...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$88K - $140K *

Drive the development of predictive analytics models to enhance digital assessment operations, collaborating across teams to optimize decision-making and reduce costs while supporting strategic goals...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.