Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Director, Revenue Cycle Jobs in South Dakota

Sort By: Relevance

$130K - $160K *

Drive program success by coordinating cross-functional teams, managing reporting, and optimizing engagement strategies for a global enterprise account, ensuring alignment with client goals and employe...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $158K *

Drive strategies to enhance customer engagement and retention for pharmacy services. Collaborate with cross-functional teams to optimize member experiences, increase auto-refill adoption, and boost pr...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Join a team that's redefining pricing strategies and business analysis. As a key member, you'll develop competitive pricing models, analyze risks, and collaborate with finance and business development...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Staffing

$120K *

Empower the national brand by leading social media strategy, driving engagement, and fostering partnerships. Oversee content creation and analytics to enhance audience reach and conversion across dive...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Media

$120K - $145K *

Join a team that's redefining payment solutions! Drive strategic product management, leading innovative card offerings and fostering high-performing teams while shaping market-leading strategies and e...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $180K *

Accelerate progress at the intersection of Treasury and Accounting, managing cash forecasting, customer collections, and disbursements. Collaborate with cross-functional teams to ensure financial inte...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$170K - $230K *

Drive strategic growth and innovation in AI-enabled assessment and workforce solutions. Lead high-impact projects, foster collaboration, and enhance AIR's national leadership in education and workforc...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Drive sustained growth as a key commercial leader by executing innovative revenue strategies, generating new client opportunities, and expanding market presence in the evolving data center and AI infr...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$97K - $190K *

Champion strategic sourcing in Design & Construction, leading procurement initiatives to optimize value and drive cost savings. Collaborate with stakeholders to enhance supplier relationships and ensu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Empower Public Safety agencies by driving sales and fostering relationships across a multi-state territory. Manage the sales cycle through consultative partnerships, ensuring pipeline growth and reven...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$70K - $106K *

Transform operational data into actionable insights while collaborating with cross-functional teams to support business decisions and enhance efficiency. Leverage analytical skills to drive performanc...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$67K - $182K *

Lead the charge in driving operational excellence and strategic direction for a high-performing underwriting team, ensuring quality Medicare underwriting services that support profitable growth and bu...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $185K *

Accelerate your career by executing regional payor strategies to secure coverage and reimbursement for innovative Surgical Glaucoma products. Collaborate with cross-functional teams and build relation...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Transform supply chain financial management by leading cost analysis, budgeting, and strategic initiatives. Empower a cross-functional team to drive operational excellence and continuous improvement a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$70K - $140K *

Lead the charge in enhancing our Partner ecosystem by managing relationships and driving growth initiatives. Oversee onboarding, operations, and support for System Integrators while implementing autom...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $140K *

Join a dynamic team to lead complex data management projects, blending Agile methodologies with technical expertise. Drive collaboration across healthcare analytics, ensuring successful delivery and s...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$225K - $275K *

Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$211K - $281K *

Champion regulatory excellence by leading U.S. FDA engagement and strategy for product development, ensuring timely approvals and compliance while driving cross-functional collaboration and organizati...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$82K - $128K *

Shape data-driven strategies by developing and automating analytics solutions. Collaborate with cross-functional teams to enhance reporting capabilities and optimize operational performance in a dynam...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $125K *

Drive new business in healthcare technology by engaging with hospitals and ambulatory organizations. Leverage AI-enabled solutions and clinical documentation services to meet client needs and achieve...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Advance your career by leading strategic partnerships, optimizing relationships, and driving revenue growth. Collaborate across teams to enhance product capabilities and market reach while managing a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$128K - $145K *

Support the full life cycle of vendor contracts, from negotiation to execution. Collaborate with stakeholders to manage legal risks and ensure compliance in a fast-paced environment, focusing on healt...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$184K - $254K *

Shape the future of Procurement by leading enterprise capabilities that enhance performance, streamline processes, and drive technology integration, ensuring measurable value and strategic alignment a...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

$203K - $290K *

Empower impactful narratives as you architect and lead a global CEO communications strategy, translating complex tech innovations into compelling stories that resonate across media and digital platfor...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$125K - $144K *

Optimize our data platform by owning end-to-end data engineering projects, leveraging AI coding agents, and ensuring data quality. Collaborate with cross-functional teams to deliver reliable, maintain...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.