Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$223K - $313K *

Lead the charge in evaluating complex clinical scenarios and authorizing services based on national guidelines and regulatory compliance. Collaborate with healthcare professionals to ensure quality ca...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$95K - $120K *

Join a team that's dedicated to improving patient care by supervising clinical operations, ensuring compliance, and developing staff in a dynamic home health environment. Embrace the opportunity to en...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$176K - $294K *

Empower a global team by leading business operations for a new Data & Intelligence organization. Drive operational excellence, enhance communication, and manage financial stewardship to foster a cultu...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a dedicated team as you lead operations in hospice care, ensuring compliance and financial success while enhancing patient experiences. Drive growth through strategic planning and marketing initi...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's dedicated to enhancing patient care by leading operations in hospice and palliative services. You'll oversee daily functions, ensure compliance, and drive growth through strategic i...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$283K - $325K *

Lead the charge in clinical compliance strategy, ensuring operational readiness and inspection preparedness across early and late-phase clinical development programs. Collaborate with cross-functional...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Oversee clinical supply chain strategy, ensuring timely delivery of investigational products for clinical studies while collaborating with cross-functional teams and external partners to adapt to chan...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Make your mark at the forefront of clinical operations, driving global studies from strategy to execution while ensuring operational integration across teams and vendors for successful Phase 3 program...

United StatesRemote

3 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Transform healthcare operations by leading multiple locations, enhancing patient experiences, and driving growth. Collaborate with teams to implement efficient systems and maintain high standards of c...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$140K - $170K *

Shape the success of enterprise health systems by leading full implementations. Collaborate cross-functionally to manage project lifecycles, mitigate risks, and ensure smooth transitions to customer s...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform clinical development operations by owning process engineering methodologies, ensuring scalable, compliant processes, and leading strategic initiatives that enhance operational excellence acr...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in evolving clinical process engineering capabilities, establishing methodologies and governance to ensure scalable, inspection-ready processes across Clinical Development Operations w...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in operational excellence within a dynamic healthcare environment, managing diverse teams and driving quality initiatives to enhance patient satisfaction and optimize performance throu...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$190K - $230K *

Unlock innovative approaches in Translational Medicine, leading biomarker strategies to bridge the gap between clinical research and development, and shaping impactful initiatives to advance drug effi...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$213K - $280K *

Lead the charge in clinical operations for early development programs, ensuring first-in-human study readiness and milestone delivery through strategic planning, vendor management, and cross-functiona...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$186K - $220K *

Empower your career by leading strategic site engagement for clinical programs. Collaborate cross-functionally to enhance study execution, improve site experiences, and drive impactful outcomes in cli...

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$203K - $284K *

Join us in providing strategic leadership for global oncology clinical trials. As a hands-on study leader, you will oversee complex studies, drive operational excellence, and contribute to the growth...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$111K - $159K *

Lead clinical operations in review of medical certifications for leave requests. Build and manage a dedicated team, standardize workflows, and ensure compliance while driving continuous improvements i...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $145K *

Transform healthcare delivery by leading interdisciplinary teams to enhance care for older adults. Drive quality improvement, ensure compliance, and foster a culture of excellence while mentoring staf...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $145K *

Champion interdisciplinary healthcare teams to enhance care for older adults, ensuring quality and compliance while fostering a culture of innovation and accountability. Lead operational excellence an...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate healthcare operations in a new market by leading strategic growth, enhancing clinic performance, and building high-performing teams while ensuring regulatory compliance and superior patient ca...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$98K - $102K *

Innovate transformative ABA services for children with autism, leading clinical excellence and mentorship. Drive program development and collaboration with educators and families to enhance individual...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$151K - $201K *

Lead large-scale distribution center operations, driving excellence in safety, quality, and financial performance while fostering a high-engagement workforce and implementing continuous improvement in...

Brampton, ONIn-Person

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Champion the clinical development strategy for neuropsychiatric programs, providing scientific leadership and overseeing study design, execution, and regulatory submissions to advance innovative treat...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$88K - $190K *

Innovate as a strategic partner, enhancing patient access operations through leadership, governance, and performance improvement in a dynamic healthcare environment. Drive initiatives, streamline proc...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.