Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$125K - $150K *

Join a dynamic team to drive operational excellence through data-driven strategies. Lead workforce planning, enhance performance metrics, and collaborate across functions to optimize patient services...

Today

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Unlock your potential as a strategic leader in operations analytics, driving workforce strategy and performance improvements across contact center and pharmacy operations. Collaborate with cross-funct...

Today

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Transform data into actionable insights as you lead workforce strategy and analytics. Collaborate across teams to optimize operations, enhance patient experiences, and drive performance improvements i...

Today

  •   8 - 10 years exp.  •   Healthcare

$156K - $215K *

Drive quality engineering excellence by leading teams to enhance testing, automation, and continuous improvement across diverse technology portfolios, ensuring robust delivery and production stability...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$247K - $334K *

Transform the safety profile of products by leading strategic assessments, guiding clinical teams, and ensuring compliance with regulatory standards throughout the product lifecycle. Collaborate acros...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform the landscape of ophthalmology research by leading operational strategies, ensuring regulatory compliance, and guiding a dedicated team. Drive high-quality, impactful human subject research...

1 month ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $105K *

Drive excellence in home health services by leading an interdisciplinary team, ensuring high-quality, client-centered care while optimizing operational efficiency and compliance with regulatory standa...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Engage in the coordination and evaluation of ambulatory care services, driving policy implementation and program development to enhance healthcare delivery across facilities. Collaborate with stakehol...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Shape the future of healthcare marketing by developing and executing strategies that enhance brand visibility and patient engagement across affiliate practices, driving growth and aligning with organi...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's dedicated to transforming lives through recovery! As a Clinical Director, you'll lead clinical staff, implement best practices, and ensure quality care for individuals facing substa...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$260K - $285K *

Champion the commercial manufacturing and supply platform, ensuring seamless operations from drug substance to distribution. Lead strategy, manage budgets, and build a high-performing team to support...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$260K - $285K *

Lead the charge in building and scaling commercial manufacturing operations, ensuring seamless supply chain management for drug products. Drive strategy, oversee vendor relations, and build a high-per...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Shape the future of academic excellence by leading a collaborative team to enhance student outcomes, drive compliance, and manage educational initiatives across multiple campuses, ensuring quality and...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$132K - $193K *

Design solutions that transform HR processes into efficient workflows, leveraging technology and AI. Collaborate with teams to identify needs, iterate on solutions, and empower users to enhance produc...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$290K - $350K *

Drive the global medical affairs strategy for oncology, leading cross-functional teams and ensuring alignment with strategic objectives, regulatory compliance, and stakeholder engagement to enhance pa...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$134K - $219K *

Drive operational excellence in Clinical Supply Logistics, leading a team to enhance processes, manage vendor relationships, and implement continuous improvements while leveraging data insights for st...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$340K - $375K *

Transform your career by leading clinical initiatives in a dynamic biotechnology environment, driving strategy for chronic hypoparathyroidism, and ensuring regulatory compliance while positively impac...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$340K - $375K *

Join a dynamic team to lead clinical strategy and execution in chronic hypoparathyroidism. Drive innovative studies, ensure patient safety, and collaborate with experts to enhance outcomes in rare dis...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate client relationships by leading Client Success teams to ensure operational excellence, proactive issue resolution, and strategic growth, while fostering collaboration across departments to enh...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $195K *

Oversee the CMC strategy for small molecules, ensuring successful development, manufacturing, and compliance with regulatory standards while collaborating across various teams and external partners...

San Diego, CARemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $195K *

Champion the development and execution of CMC strategies for small molecules, ensuring timely and budget-compliant manufacturing through collaboration across multiple departments and with external par...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$248K - $373K *

Drive regional performance in population health initiatives, overseeing clinician management and network development. Collaborate with leadership to enhance care quality and efficiency while supportin...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion high-quality hospice care by leading clinical and operational teams, ensuring compliance and excellence across home and inpatient settings. Drive performance and collaboration while supportin...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Elevate patient services by providing strategic leadership and operational oversight in a clinical setting, ensuring exceptional customer service, staff development, and compliance with regulatory sta...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Unlock the potential of clinical documentation improvement by leading initiatives, enhancing team performance, and ensuring compliance with regulatory standards. Collaborate with healthcare profession...

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.