Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Associate Director, Strategic Planning
$110K - $130K *
Join a team that's redefining strategic planning in healthcare. Collaborate with experts to develop innovative, multichannel strategies, driving insights and brand growth while leading diverse project...
2 weeks ago
Associate Director, Strategic Planning
$110K - $130K *
Optimize your career by leading strategic planning initiatives, synthesizing insights, and collaborating with cross-functional teams to drive innovative solutions in the healthcare and pharma sectors...
2 weeks ago
Director of Clinical Reimbursement - MDS/PDPM
$110K - $130K *
Unlock your potential by leading clinical reimbursement and compliance across a multi-site skilled nursing portfolio. Collaborate closely with clinical teams to optimize documentation, reimbursement s...
Reposted 3 weeks ago
$100K - $120K *
Drive operational excellence in physician services by leading recruitment, onboarding, and strategic initiatives. Collaborate with clinical leaders to enhance performance and support decision-making t...
Today
Senior Manager, Quality Program Management
$125K - $150K *
Join a team that's committed to ensuring quality excellence in cell therapy. Oversee integrated project plans, coordinate efforts across departments, and lead initiatives to enhance compliance and ope...
4 weeks ago
Associate Director, Clinical Data Management
$187K - $230K *
Elevate your career by leading Clinical Data Management initiatives, ensuring compliance and quality across clinical trials. Collaborate with cross-functional teams to drive data integrity and operati...
2 weeks ago
Executive Director Epic Revenue Cycle Applications
$170K - $200K *
Lead the strategy and performance of Epic revenue cycle applications, guiding a team to optimize solutions that align with organizational goals. Collaborate with leadership to shape technology roadmap...
Yesterday
Chief Operating Officer - UCHealth Medical Group
$346K - $500K+*
Lead the charge in operational excellence for a physician-led group, driving strategic initiatives and enhancing patient care across multiple regions. Collaborate with senior leadership to ensure high...
Reposted yesterday
Associate Director, Integrated Insights & Analytics, Nephrology
$162K - $222K *
Unlock potential by leading insights for key assets, driving strategic decisions through market research and analytics. Collaborate cross-functionally to translate complex data into actionable narrati...
Today
Associate Medical Director -Oncology
$120K - $130K *
Help us innovate educational initiatives for healthcare professionals by developing high-quality medical content in oncology. Collaborate across teams to enhance clinical knowledge and improve patient...
Today
Director, Medical Specialty Practices
$120K - $160K *
Drive operational excellence and strategic growth in medical specialty practices, ensuring high-quality patient care and efficient operations while collaborating with leadership to enhance service del...
1 week ago
Senior Director, Statistical Programming
$228K - $311K *
Lead strategic initiatives in Statistical Programming, guiding teams and managing resources to ensure effective data analysis and reporting across clinical studies. Drive innovation and maintain indus...
1 week ago
$95K - $115K *
Lead the charge in operational excellence for a new clinic, driving service delivery and team development while collaborating across functions to enhance patient care and achieve key performance indic...
2 weeks ago
$95K - $115K *
Unlock operational excellence by leading clinic operations and team development. Collaborate cross-functionally to enhance patient care and drive key performance indicators while fostering a culture o...
3 weeks ago
Associate Director, Clinical Data Management
$142K - $224K *
Join us in advancing clinical data standards and governance. Lead teams, mentor staff, and ensure compliance with industry regulations while driving high-quality data collection processes across thera...
Today
Associate Director, Clinical Data Management
$142K - $224K *
Drive operational excellence by leveraging data analytics to optimize portfolio and resource management. Collaborate with cross-functional teams to enhance visibility and standardization, ensuring inf...
Today
Associate Director, Clinical Data Management
$142K - $224K *
Join a team that's driving operational excellence through data analytics and resource management. Collaborate across functions to enhance visibility, optimize performance, and ensure informed decision...
Today
Associate Director, Clinical Data Management
$142K - $224K *
Join a team that's shaping clinical data standards by overseeing data collection processes, guiding study teams, and mentoring staff to ensure compliance with industry regulations and best practices a...
Today
$75K - $95K *
Champion operational excellence by leading clinic operations, enhancing team performance, and driving key metrics. Collaborate cross-functionally to deliver exceptional patient care while navigating c...
3 weeks ago
Clinical Director, Infusion - PPMC
$110K - $130K *
Champion clinical excellence by leading ambulatory care operations, ensuring compliance, and driving quality improvement initiatives. Collaborate with leadership to enhance patient care and optimize d...
1 week ago
Senior Director, Data Operations & Enablement
$265K - $307K *
Shape the future of commercial data operations by leading a multidisciplinary team to ensure data reliability, quality, and integration. Drive strategic initiatives while managing day-to-day operation...
1 week ago
Senior Director, Data Operations & Enablement
$265K - $307K *
Pioneer the commercial data operations landscape, ensuring data quality, integration, and scalability. Lead a multidisciplinary team to transform data into trusted analytics-ready products while drivi...
1 week ago
Director, Commercial Operations Gene Therapy
$150K - $180K *
Lead commercial operations at our gene therapy site, driving key client relationships and ensuring seamless integration of services for successful outcomes. Collaborate across teams to optimize pricin...
3 weeks ago
$204K - $249K *
Unlock the potential of drug product development by leading cross-functional teams in advancing siRNA/oligonucleotide and small molecule formulations, ensuring timely delivery of high-quality investig...
2 weeks ago
$150K - $180K *
Join a team that's redefining business operations by leading and executing strategic initiatives. Collaborate closely with executive leadership to drive performance metrics and optimize staffing for m...
4 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.