Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$175K *

Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$179K - $238K *

Empower clinical excellence by leading operations, education, and supply chain initiatives. Collaborate with executive leadership to standardize practices, enhance patient safety, and drive quality ou...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$254K - $347K *

Champion program management excellence by leading cross-functional teams, driving project strategies, and ensuring timely delivery of milestones in a dynamic pharmaceutical environment. Foster collabo...

1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$200K - $240K *

Join a dynamic clinical leadership team to coach and develop providers while delivering direct patient care in senior living communities, ensuring high-quality clinical performance and fostering commu...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive clinical excellence by supervising nursing staff in Ambulatory Infusion Centers, ensuring compliance with safety and accreditation standards while fostering effective communication and collabora...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Champion excellence in nursing leadership by overseeing infusion services, ensuring compliance with healthcare standards while fostering teamwork and quality care across all clinic locations...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in ensuring safe, compliant infusion services while managing nursing staff, fostering a collaborative environment, and upholding nursing standards in our Ambulatory Infusion Centers ac...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join a team that's shaping clinical sales strategies and enhancing client relationships. Lead initiatives that drive market growth and improve patient satisfaction while collaborating across disciplin...

Harrisburg, PARemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Shape strategic initiatives by collaborating with leadership to enhance community health outcomes, drive fundraising efforts, and oversee data governance, ensuring sustainable growth and impactful par...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$156K - $261K *

Elevate compliance operations by leading SOX testing, software asset management, and consulting across privacy and anti-bribery. Drive efficiency, manage budgets, and foster team engagement while ensu...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $261K *

Shape the future of compliance operations by leading SOX testing, software asset management, and compliance consulting. Drive operational efficiency and continuous improvement while managing budgets a...

Philadelphia, PARemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Unlock your potential by leading a dedicated hospice team, ensuring comprehensive patient care through collaboration, oversight, and continuous improvement in a supportive environment focused on end-o...

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Join us in overseeing end-to-end clinical supply management for global studies, focusing on demand planning, global distribution, and cross-functional leadership to ensure compliant and cost-effective...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$191K - $253K *

Shape the future of clinical development by optimizing biometrics systems and workflows. Collaborate with cross-functional teams to enhance data analytics, drive process improvements, and ensure compl...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$148K - $195K *

Lead device strategy and oversight in clinical drug development, ensuring integration of device-related activities across the clinical lifecycle. Collaborate with cross-functional teams to drive proac...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform patient care by leading high-acuity programs, ensuring operational excellence and a seamless experience from inquiry to post-discharge. Collaborate with clinical and financial teams to enhan...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$148K - $195K *

Champion device strategy by leading end-to-end clinical trial device activities, ensuring alignment across teams and stakeholders while driving proactive decision-making throughout the clinical develo...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Accelerate operational excellence by leading non-medical home care services across Arizona. Drive staffing, compliance, and quality assurance to ensure compassionate care for clients, while supporting...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Deliver high-quality, person-centered care in skilled nursing facilities, providing clinical leadership while enjoying flexible schedules that prioritize patient care and your work-life balance. Join...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $118K *

Elevate patient care by leading a dedicated team of nurses and social workers, ensuring high-quality, individualized support for high-needs patients through effective management and community partners...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Manage clinical operations while leading a team of healthcare professionals to ensure high-quality, effective psychiatric care for adult patients in an in-patient setting...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $90K *

Drive operational excellence by leading a diverse team, ensuring compliance, optimizing workflows, and enhancing service delivery while fostering a collaborative workplace culture and supporting emplo...

Laval, QCIn-Person

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $90K *

Unlock potential by leading a dynamic team in clinical operations, ensuring compliance, optimizing workflows, and fostering a collaborative culture while enhancing service delivery and client satisfac...

Cornwall, ONIn-Person

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $90K *

Transform healthcare delivery by leading a dynamic team, optimizing operations, and ensuring compliance. Drive client satisfaction and foster a collaborative culture while enhancing employee developme...

Montreal, QCIn-Person

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $90K *

Join us to lead and optimize clinical operations, ensuring high-quality service delivery while fostering a collaborative workplace culture. Drive compliance, employee development, and client satisfact...

Toronto, ONIn-Person

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.