Clinical Trial Managers oversee the planning and execution of clinical studies, helping ensure trials meet scientific, operational, regulatory, and ethical requirements. They coordinate cross-functional teams, manage timelines and budgets, and monitor progress from study startup through closeout. Explore vetted Clinical Trial Manager opportunities with compensation of $100,000 or more on Ladders.
Responsibilities vary by employer and study, but commonly include developing trial plans, coordinating clinical research organizations and sites, tracking enrollment and milestones, managing study budgets, and identifying operational risks. Clinical Trial Managers also support compliance with protocols, Good Clinical Practice (GCP), and applicable regulatory requirements, while communicating updates to sponsors, investigators, and internal stakeholders.
Employers often seek experience in clinical research or trial operations, strong project management and communication skills, and the ability to manage multiple priorities. Familiarity with GCP, clinical trial regulations, study documentation, and systems such as electronic data capture platforms can be valuable. A degree in life sciences, nursing, public health, or a related field is common; some positions may prefer advanced education or relevant certifications.
Clinical Trial Managers work for pharmaceutical and biotechnology companies, contract research organizations, academic medical centers, and other research organizations. Opportunities may focus on a therapeutic area, phase of development, or regional portfolio. With experience, professionals may advance to senior trial management, clinical operations leadership, or program management roles.
Search Ladders for Clinical Trial Manager jobs and related clinical operations opportunities. Compare roles by responsibilities, experience requirements, work arrangement, and compensation to find positions that align with your career goals.
Supervisor, Program Management
$80K - $95K *
Join a team that's dedicated to operational excellence and employee development. As a Supervisor, you'll lead daily operations, manage performance, and ensure compliance while fostering a collaborativ...
1 week ago
$135K - $170K *
Join a team that's driving innovative clinical research across multiple regions, leading teams to ensure on-time deliverables and high-quality data management in complex trials. Support site managemen...
Reposted 1 week ago
$118K - $172K *
Join a team that's dedicated to overseeing the radiology department, ensuring operational excellence, compliance with regulations, and fostering staff development while managing budgets and strategic...
1 week ago
Senior Manager, Patient Engagement, Oncology
$110K - $130K *
Join a team that's redefining oncology recruitment marketing by leading innovative strategies across multiple sites, enhancing patient engagement, and driving enrollment efficiency through targeted ca...
3 weeks ago
Senior Director, Operational Strategy - Oncology
$150K - $180K *
Elevate your career by leading oncology strategy initiatives, developing competitive approaches for awards, and fostering client relationships to enhance business growth in a dynamic, collaborative en...
4 weeks ago
Senior Director, Operational Strategy - Oncology
$150K - $180K *
Champion innovative oncology strategies by coordinating pre-award activities, enhancing client relations, and collaborating with global teams to drive successful outcomes in clinical research and busi...
4 weeks ago
Senior Director, Operational Strategy - Oncology
$160K - $200K *
Lead the charge in developing competitive oncology strategies, ensuring client needs are met through collaboration and expertise. Drive business development and enhance client relations while overseei...
4 weeks ago
Senior Clinical Research Associate (East Coast based)
$95K - $115K *
Elevate clinical research by ensuring investigational sites meet study standards. Conduct monitoring visits, train staff, and support regulatory submissions while mentoring junior team members in a dy...
2 days ago
$136K - $181K *
Take ownership of CRA management by leading teams, developing metrics, and ensuring compliance with monitoring standards. Drive continuous improvement and optimize effectiveness across the Site Manage...
2 days ago
Senior Clinical Research Associate (East Coast based)
$95K - $115K *
Champion clinical excellence by conducting comprehensive monitoring visits, ensuring investigational sites meet study requirements, and training staff to uphold the highest standards throughout the cl...
2 days ago
Senior Clinical Research Associate (East Coast based)
$110K - $130K *
Join a dynamic team to oversee clinical study monitoring, ensuring compliance and quality at investigational sites. Engage in training, mentoring, and regulatory support while contributing to impactfu...
2 days ago
Senior Clinical Research Associate (East Coast based)
$95K - $115K *
Join a dynamic team to ensure clinical study integrity through comprehensive monitoring, training, and regulatory support. Your expertise will enhance trial success and patient safety in complex oncol...
2 days ago
Director, GDO Trial Performance Intelligence & Strategy
$177K - $278K *
Transform trial performance through strategic insights and data governance, enhancing decision-making and accelerating delivery. Lead cross-functional partnerships to drive measurable improvements in...
1 week ago
Sr. Clinical Research Associate
$95K - $115K *
Join a team that's dedicated to advancing clinical research by ensuring compliance and quality in trials. You'll monitor sites, conduct visits, and collaborate with teams to uphold the highest standar...
1 week ago
Director, Clinical Quality Assurance
$195K - $256K *
Elevate clinical quality assurance by designing and executing strategies for compliance, audit management, and oversight of global clinical operations. Collaborate with stakeholders to ensure adherenc...
1 week ago
Director, Clinical Quality Assurance
$195K - $256K *
Champion the North America Clinical Quality Assurance strategy, overseeing audits, inspections, and compliance with regulations. Lead a team to ensure adherence to Good Clinical Practice and enhance q...
1 week ago
Protocol Project Manager (Sr. CRC) - Gastrointestinal Oncology Program
$95K - $115K *
Accelerate progress at the forefront of clinical research by managing oncology trials. Serve as the key liaison among study teams, sponsors, and departments, ensuring compliance and smooth operations...
Yesterday
Manager, Research Administration - Clinical Trials
$88K - $104K *
Join a team that's driving innovation in vaccine research through comprehensive administrative leadership, overseeing grant management, regulatory compliance, and operational strategies to support cli...
Reposted 2 days ago
Manager, Regulatory Operations (Remote)
$110K - $135K *
Join us in leading a dynamic Regulatory Operations team to ensure timely, compliant submissions and maintain inspection-ready files. Drive process improvements and collaborate across departments to su...
3 days ago
Manager, Regulatory Operations (Remote)
$110K - $135K *
Accelerate progress at the forefront of regulatory operations, leading a dedicated team to ensure timely, compliant submissions and maintenance of Investigator Site Files, while driving process improv...
3 days ago
$110K - $130K *
Manage a dynamic project management team, ensuring strategic delivery of high-impact programs while fostering team growth and adherence to PMO standards. Drive successful project outcomes through effe...
2 weeks ago
$110K - $130K *
Lead the charge in strategic program management, overseeing project delivery and team development. Drive successful outcomes through effective staffing, risk management, and stakeholder collaboration...
2 weeks ago
$80K - $95K *
Transform customer project delivery by managing timelines, scope, and quality. Collaborate cross-functionally to ensure successful execution and foster strong client relationships while driving innova...
6 days ago
Clinical Research Project Manager - Thoracic Oncology
$76K - $85K *
Transform clinical trial management by overseeing multi-center oncology studies. Ensure compliance, coordinate operations, and support research staff while maintaining project timelines and regulatory...
3 weeks ago
Senior Site Activation Manager (US)
$107K - $213K *
Oversee site activation projects, ensuring timely delivery, effective communication, and compliance with regulations. Lead cross-functional teams to meet goals and address challenges, driving strategi...
Reposted 1 week ago
What does a Clinical Trial Manager do?
A Clinical Trial Manager plans and coordinates clinical studies, overseeing timelines, budgets, vendors, research sites, study teams, and operational compliance from startup through closeout.
What qualifications are typically required for Clinical Trial Manager jobs?
Many roles require clinical research or trial operations experience, project management skills, and knowledge of GCP and relevant regulations. Employers commonly seek a degree in life sciences, nursing, public health, or a related area.
Where do Clinical Trial Managers work?
They work at pharmaceutical and biotechnology companies, contract research organizations, academic medical centers, and other organizations that sponsor or conduct clinical research.
How can I find Clinical Trial Manager jobs paying $100,000 or more?
Browse vetted Clinical Trial Manager openings on Ladders, where listed opportunities pay $100,000 or more. Review each posting for compensation details, qualifications, and work arrangement.