Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing companies. Whether you’re looking for a leadership position or your next specialized role, find opportunities that match your experience and career goals.

Career opportunities across California

California’s broad economy offers roles in fields such as technology, entertainment, healthcare, finance, biotechnology, clean energy, and professional services. Opportunities can be found in major employment centers including Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and other communities throughout the state. Job availability and compensation vary by employer, location, role, and qualifications.

Find roles that fit your experience

Use job details to compare responsibilities, required skills, work arrangements, and compensation. Search for positions by title, industry, or location, and review each listing for its specific salary range and requirements. Tailor your resume to highlight relevant results, expertise, and leadership experience when applying.

Search California jobs on Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more. Explore California listings to identify opportunities aligned with your background, preferred location, and next career move. Listings change frequently, so check back for newly available roles.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$119K - $234K *

Join a team that's building cutting-edge AI infrastructure for frontier model development. Collaborate with experts to enhance compute orchestration and scheduling, driving efficiency and reliability...

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Take ownership of software engineering initiatives within established companies. Lead teams, modernize development processes, and enhance code quality while delivering impactful software solutions. Co...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$118K - $143K *

Innovate tissue-based assays and histological techniques to advance novel radiopharmaceutical therapies. Collaborate with interdisciplinary teams to support preclinical and clinical research through m...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$119K - $234K *

Partner with us to build and operate scalable API services for MAI models, ensuring training and production parity. Collaborate across teams to automate model deployment and enhance system reliability...

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$161K - $190K *

Join us to define and evolve the architecture of a cutting-edge digital platform, guiding engineering decisions and establishing shared services for scalable, secure, and reliable solutions that empow...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$85K - $115K *

Elevate healthcare education by developing evidence-based content for clinicians. Collaborate with experts to create innovative learning materials that address practice gaps and enhance professional s...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $190K *

Unlock potential by leading data-driven GTM strategy and analytics. Collaborate with Sales, Finance, and leadership to refine revenue forecasts, build models, and deliver insights that drive business...

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$215K - $235K *

Shape high-impact production strategies for non-scripted formats, collaborating with internal teams and external partners to ensure projects are delivered on time and within budget while fostering str...

Yesterday

  •   11 - 15 years exp.  •   Media

$215K - $235K *

Unlock potential by overseeing production management for non-scripted formats, collaborating with internal and external teams to ensure projects are on-budget and on-schedule while fostering strong cl...

Yesterday

  •   11 - 15 years exp.  •   Media

$100K - $120K *

Join a team that's dedicated to fostering educational excellence through collaboration and innovation. This role involves overseeing key administrative functions and supporting the development of teac...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$109K - $130K *

Lead the charge in delivering exceptional client service and strategic immigration solutions. Collaborate with diverse teams to optimize processes, manage relationships, and drive business growth in a...

Yesterday

  •   8 - 10 years exp.  •   Legal & Accounting

$170K - $185K *

Lead the charge in managing a high-performing clinical operations team, driving the execution of in-house clinical trials with a focus on quality, resource allocation, and staff development, while ens...

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$93K - $120K *

Help us advance student wellness by providing clinical case management and support. Collaborate with diverse stakeholders to enhance mental health services and promote inclusive excellence within the...

Reposted yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$88K - $92K *

Lead the charge in advancing winds performance education through innovative teaching, mentorship, and collaboration. Shape the future of aspiring musicians while contributing to a vibrant artistic com...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$228K - $342K *

Empower your career by leading strategic project management initiatives across early drug development. Drive process optimization, cultivate high-performing teams, and collaborate with executives to a...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in optimizing revenue cycle operations, ensuring compliance and efficiency across Prior Authorization and Medical Billing teams while driving measurable improvements in performance and...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in innovative AI solutions, driving impactful projects with a small, agile team. Collaborate across disciplines to tackle complex challenges and deliver exceptional results in a fast-p...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$88K - $92K *

Transform the future of winds performance by leading innovative teaching and mentoring in a dynamic music department. Engage with diverse students and contribute to artistic excellence while maintaini...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$86K - $88K *

Join a team that's dedicated to enhancing donor relationships and expanding equity-focused programming. Play a key role in developing strategies to secure corporate and foundation support, ensuring di...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$124K - $158K *

Elevate patient care by conducting comprehensive medication reviews and consultations. Collaborate with prescribers to optimize therapy, enhance adherence, and improve health outcomes in a remote, pat...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$118K - $166K *

Join a team that's dedicated to enhancing critical water and wastewater systems. Lead a specialized group in maintaining process control technologies, ensuring cybersecurity, and collaborating with di...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead the charge in expanding our global Advisory business by driving business development, overseeing project delivery, and mentoring a diverse team of consultants to address complex client challenges...

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $110K *

Advance your career by conducting vital physical security evaluations across multiple data centers. Collaborate with teams to enhance security measures and protect critical infrastructure while engagi...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$392K - $450K *

Drive the strategic direction of the Neurology Clinical Development team, overseeing clinical programs and lifecycle management to ensure innovative treatments reach patients effectively and efficient...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, biotechnology, entertainment, clean energy, and other industries. Available positions depend on current employer hiring needs.

  • Which California cities have professional job opportunities?question toggle

    Opportunities may be listed in Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and other cities and regions across the state. Search by location to see current openings.

  • Do all jobs listed in California pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more. Review each listing for its specific compensation details, since salary ranges and terms can vary.

  • How can I find a California job that matches my experience?question toggle

    Search by job title, location, or industry, then compare each listing’s responsibilities and qualifications with your background. Highlight relevant skills and measurable accomplishments in your application.

  • Are remote or hybrid California jobs available?question toggle

    Some employers may offer remote or hybrid arrangements, while others require on-site work. Check each job listing for its work location and arrangement.