Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.
California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.
Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.
Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.
Average Salary: $142,597
Pharmacy Supervisor - Clinical MTM and Specialty Projects
$148K - $352K *
Champion clinical pharmacy operations by overseeing Medication Therapy Management, ensuring compliance, and leading a team of pharmacists and technicians to enhance patient care and operational effici...
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General Manager (Sausalito, CA)
$240K - $265K *
Champion exceptional guest experiences by leading operations, driving revenue, and fostering community relations. Collaborate with teams to uphold high standards and ensure compliance while nurturing...
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Senior Mechatronics & Robotics Technician
$76K - $89K *
Join a team that's dedicated to advancing automated systems by leading the installation and repair of cutting-edge packaging equipment. Mentor technicians while driving innovative solutions and ensuri...
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$175K - $200K *
Transform marketing strategies to elevate brand reputation and leasing performance across a multifamily portfolio. Collaborate with leadership to drive growth, enhance resident experiences, and lead a...
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PSR/Scheduler - Oncology, Atascadero
$66K - $95K *
Engage with physicians and patients to facilitate communication and access to services. Act as a liaison, ensuring smooth operations within the health system while providing essential support for prim...
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Field Activation Specialist, HIV Prevention - CA Central Valley
$115K - $149K *
Unlock growth by engaging healthcare providers, driving sales, and managing accounts in high-need areas. Collaborate with cross-functional teams to deliver impactful solutions and exceed sales targets...
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$95K - $125K *
Empower the executive team by driving operational excellence, managing diverse projects, and enhancing team efficiency. This dynamic role requires adaptability and problem-solving skills to tackle evo...
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$140K - $160K *
Champion the growth of partnerships by driving outreach, nurturing leads, and collaborating closely with leadership. Play a key role in scaling operations and establishing a successful partnership cha...
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$135K - $145K *
Deliver seamless integration and Tier 3 support for secure mobile infrastructure. Collaborate with enterprise stakeholders to ensure compliance, performance, and customer satisfaction while managing c...
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Senior Project Manager, Multiport (New Product Development)
$120K - $145K *
Advance your career by leading cross-functional teams in innovative surgical robotics projects. Drive product development from conception to market, ensuring timely delivery and compliance with design...
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Field Activation Specialist, HIV Prevention - CA Central Valley
$115K - $149K *
Unlock potential by driving sales and fostering relationships with healthcare providers. This role emphasizes strategic account management and collaboration to enhance patient access to innovative the...
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Field Activation Specialist, HIV Prevention - CA Central Valley
$115K - $149K *
Transform healthcare by engaging providers and driving sales in high-need areas. Leverage your expertise to build relationships, deliver impactful education, and exceed targets while collaborating wit...
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Sr. Software Engineer - Sensor, macOS (Hybrid)
$140K - $220K *
Champion innovation in macOS development, driving core sensor features for endpoint protection. Collaborate with a dynamic team to enhance security capabilities, ensuring high performance and reliabil...
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Senior Lead of Marketing Operations & MarTech
$170K - $190K *
Accelerate progress at the forefront of marketing operations by architecting and optimizing global MarTech systems, ensuring seamless data governance and campaign execution to drive high-impact result...
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Regional Manager LIHTC/HUD/RD - IE/Desert
$80K - $95K *
Grow your career with us as you manage residential properties, ensuring financial viability and operational excellence while leading a dedicated team and fostering strong relationships with stakeholde...
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Senior Scientist Directed Energy Protection
$135K - $166K *
Engage with a dynamic team to lead the development of innovative optical protection technologies. Drive projects from ideation to execution, ensuring alignment with strategic goals while fostering col...
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$155K *
Transform complex challenges into impactful software solutions. Collaborate with engineers, designers, and justice leaders to drive product strategy and execution, enhancing the criminal justice syste...
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Executive Director, Business & Legal Affairs
$179K - $250K *
Collaborate to shape strategic legal and business frameworks for creator partnerships, production, and technology initiatives, driving innovative deal structures in a dynamic media landscape...
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$80K - $95K *
Help us shape the future of construction projects by leveraging your engineering expertise. Collaborate with diverse teams to ensure successful project execution, manage budgets, and maintain effectiv...
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Technical Program Manager, Pretraining Data
$119K - $234K *
Advance your career by driving complex data programs that support large-scale AI model training. Collaborate with cross-functional teams to ensure timely execution and quality of data releases while n...
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Compute Orchestration & Scheduling
$119K - $234K *
Join a team that's building cutting-edge AI infrastructure for frontier model development. Collaborate with experts to enhance compute orchestration and scheduling, driving efficiency and reliability...
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$135K - $160K *
Take ownership of software engineering initiatives within established companies. Lead teams, modernize development processes, and enhance code quality while delivering impactful software solutions. Co...
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$118K - $143K *
Innovate tissue-based assays and histological techniques to advance novel radiopharmaceutical therapies. Collaborate with interdisciplinary teams to support preclinical and clinical research through m...
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Software Engineer, Model API Infra
$119K - $234K *
Partner with us to build and operate scalable API services for MAI models, ensuring training and production parity. Collaborate across teams to automate model deployment and enhance system reliability...
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$161K - $190K *
Join us to define and evolve the architecture of a cutting-edge digital platform, guiding engineering decisions and establishing shared services for scalable, secure, and reliable solutions that empow...
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What types of $100,000+ jobs can I find in California?
California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.
Where in California can I search for jobs?
You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.
Can I find remote or hybrid California jobs?
Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.
How can I improve my California job search?
Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.