Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$251K - $310K *

Elevate your career by managing a global patent portfolio in cutting-edge technology. Collaborate with cross-functional teams to advise on IP issues, ensuring strategic alignment and risk management i...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform cloud communication systems by optimizing existing architectures, driving AI innovations, and leading technical teams to enhance performance and integrations across enterprise platforms...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$70K - $105K *

Lead sales initiatives for consumable and diagnostic lab supplies, fostering customer relationships and driving market growth within a defined territory while achieving sales and profit targets...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $245K *

Accelerate progress at our organization by managing and scaling partner relationships. You'll define programs that connect technology partners with internal teams, driving innovation and enhancing use...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $100K *

Develop strategic customer relationships and expand international presence by acquiring new enterprise clients and nurturing existing accounts in the pharmaceutical and life sciences sectors...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$83K - $101K *

Unlock potential by delivering skilled occupational therapy interventions under supervision. Collaborate with a dynamic team to enhance patient care, monitor progress, and support rehabilitation goals...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$70K - $97K *

Optimize executive operations by managing complex schedules, coordinating meetings, and streamlining processes in a fast-paced public relations environment for high-level leaders in the movie industry...

Reposted today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$85K - $100K *

Provide professional nursing care by assessing, planning, implementing, and evaluating patient needs. Collaborate with healthcare teams to ensure quality care and support clinic objectives while maint...

Today

  •   Less than 5 years exp.  •   Healthcare

$194K - $267K *

Partner with us to enhance Product & Technology operational excellence by leading cross-functional teams toward strategic goals, improving decision-making, and driving quality in execution. Leverage c...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Elevate your career by transforming a Microsoft Entra environment into an enterprise-ready platform. Collaborate across teams to enhance security, governance, and operational efficiency while implemen...

Today

  •   Less than 5 years exp.  •   Information Technology

$165K - $223K *

Drive innovation in large-scale machine learning systems, collaborating with teams to design, develop, and deploy robust solutions. Influence strategy and mentor junior engineers while optimizing perf...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$176K - $239K *

Advance your career by designing innovative AI/ML solutions, guiding clients through technical challenges, and collaborating across teams to enhance adoption and strategy in a dynamic environment...

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$160K - $190K *

Join us to shape the future of observability by architecting scalable telemetry solutions, driving cross-team collaboration, and mentoring engineers to enhance system reliability and performance acros...

Today

  •   8 - 10 years exp.  •   Information Technology

$120K - $180K *

Join a team that's dedicated to providing exceptional veterinary care while enjoying flexible scheduling and comprehensive benefits. Collaborate with a supportive network and explore future ownership...

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Innovate media strategies in Oncology, collaborating with brand teams to execute impactful campaigns across traditional and digital channels, ensuring alignment with business goals and driving results...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$101K - $132K *

Contribute to impactful cross-functional initiatives, enhancing Agile practices and operational efficiency. Collaborate with leaders to drive strategic alignment, visibility, and effective execution a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$117K - $210K *

Unlock potential by leading complex health and benefits financial strategies. Leverage your actuarial expertise to drive client success, enhance plan performance, and foster innovative solutions acros...

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$83K - $93K *

Join a collaborative team to develop and implement tailored speech therapy plans for diverse learners, fostering communication skills and resilience in students while maintaining accurate documentatio...

Today

  •   Less than 5 years exp.  •   Staffing

$165K - $228K *

Pioneer the design and delivery of complex multi-domain systems, leading cloud, data, and AI initiatives. Collaborate with cross-functional teams to define architecture, mentor engineers, and drive te...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$145K - $160K *

Engage with patients to deliver exceptional care, navigate complex healthcare systems, and collaborate with an integrated team. Your role will focus on holistic assessments, patient education, and tai...

Today

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Join a dynamic team to drive Financial Planning & Analysis, influencing strategic decisions and enhancing operational efficiency in a rapidly growing Cloud business. Your expertise will shape financia...

Today

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

Support financial planning and analysis for our growing Cloud business. Drive strategic decisions through detailed financial modeling, cost analysis, and competitive intelligence while enhancing opera...

Today

  •   Less than 5 years exp.  •   Information Technology

$88K - $120K *

Explore innovative marketing automation solutions by collaborating with teams to implement Salesforce Marketing Cloud technologies, ensuring high-quality execution and strategic alignment for client c...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$85K - $128K *

Join a dynamic team to drive integration and testing for complex enterprise solutions. Collaborate across engineering disciplines to ensure cohesive system functionality and deliver innovative technic...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Aerospace & Defense

$85K - $90K *

Unlock potential by analyzing and optimizing order requirements to enhance distribution efficiency, ensuring timely delivery and mitigating supply risks while fostering strong partnerships with Teamin...

Reposted today

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.