Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Sr Life Underwriting Business Systems Analyst
$85K - $100K *
Champion life underwriting transformation initiatives by analyzing requirements, facilitating project lifecycles, and collaborating with cross-functional teams to enhance operational excellence and im...
1 week ago
Revenue Enablement Program Manager II
$91K *
Champion cross-functional programs that drive strategic outcomes, ensuring alignment with organizational priorities. Lead complex initiatives, manage risks, and foster stakeholder engagement to delive...
1 week ago
Technology Partnerships Manager - Americas
$70K - $105K *
Optimize partnerships with leading technology vendors to drive revenue growth and market presence. Collaborate cross-functionally to align strategies and co-sell initiatives, while effectively managin...
Reposted 4 days ago
$140K - $190K *
Join a team that's pioneering maritime awareness solutions by leading commercial sales in diverse sectors. Own the end-to-end sales pipeline, identify target verticals, and shape strategies to drive s...
Reposted 3 weeks ago
Director - Portfolio Valuation & Decision Analysis
$112K - $236K *
Drive strategic decision-making by evaluating investment alternatives and lifecycle opportunities. Collaborate with cross-functional teams to optimize portfolio value and support program planning thro...
1 week ago
Director, Cost of Care Solutions
$129K - $162K *
Unlock potential by leading enterprise-wide Cost of Care solutions. Drive scalability, optimize deployment, and enhance operational effectiveness across diverse markets, collaborating with stakeholder...
Reposted 1 week ago
Domain Architect (Technology Integration Management Office)
$114K - $190K *
Lead the charge in crafting target-state architecture that integrates business processes, applications, and data. Your role will shape enterprise transformation while ensuring alignment with strategic...
Reposted 2 weeks ago
$125K - $150K *
Unlock growth by leading RevOps initiatives that enhance acquisition, strengthen pipelines, and optimize seller performance through data-driven strategies and robust analytics, ensuring alignment with...
Reposted 6 days ago
Director - Digital Experience & Strategy (Practice Desktop)
$135K - $160K *
Shape the future of digital experiences for financial advisors, leading a team to enhance practice growth through AI-driven insights and strategic initiatives. Drive cross-functional collaboration and...
Yesterday
$85K - $100K *
Join a dynamic team as you drive data integrity and enhance client reporting through Addepar. Leverage your analytical skills and operations experience to support private investment processes and coll...
1 week ago
Director, Business Operations - Products & Platforms
$160K - $195K *
Drive operational excellence and lead a high-performing team to deliver complex digital products. Collaborate with cross-functional teams to define strategies, manage resources, and ensure profitable...
2 weeks ago
$110K - $130K *
Accelerate progress at key global brand relationships in personal care. Manage diverse accounts, develop sales strategies, and collaborate cross-functionally to drive growth and enhance customer exper...
1 week ago
Department Manager: Physical Design Engineer
$174K - $296K *
Champion the growth of a substation engineering practice by leading a diverse team, driving operational excellence, and delivering innovative solutions for utility clients nationwide while ensuring te...
Reposted 4 weeks ago
$200K - $235K *
Transform public safety operations by driving growth through strategic sales and relationship-building with fire departments and agencies. Own the sales cycle, deliver impactful demos, and collaborate...
1 week ago
Senior Program Manager - Data Center Construction
$110K - $130K *
Take ownership of large-scale construction projects, managing stakeholders and ensuring compliance. Oversee project governance, track milestones, and enhance processes while fostering client relations...
Yesterday
$120K - $145K *
Join a dynamic team as you drive product strategy and AI integration, ensuring innovative solutions meet market needs. Collaborate cross-functionally to enhance user experiences and deliver high-value...
2 days ago
Senior Named Account Sales Director, Frontier AI & Enterprise
$145K - $220K *
Join a team that's shaping the future of AI by leading enterprise sales for innovative AI solutions. Engage with top security and AI leaders to drive impactful evaluations and foster long-term partner...
6 days ago
Account Manager- Smart Mfg & Industry 4.0
$80K - $95K *
Champion growth in smart manufacturing by managing key accounts, driving sales, and fostering relationships within the Industry 4.0 ecosystem. Leverage technical expertise to support IIoT adoption and...
2 weeks ago
Applications Management Director
$145K - $175K *
Elevate enterprise application strategy by leading a dynamic team to align technology with business goals, ensuring optimal portfolio management, user experience, and measurable outcomes for sustained...
Today
Senior Copywriter, Promotional Medical Writing
$80K - $100K *
Advance impactful medical communications by crafting precise, engaging content. Collaborate with cross-functional teams to ensure accuracy and alignment with client objectives while mentoring junior s...
6 days ago
Vice President Sales - Data Ops
$200K - $250K *
Drive transformative enterprise sales by pioneering BGO's AI-first strategy. As the first seller, you'll build a robust pipeline, shape the sales playbook, and establish BGO as a leader in innovative...
2 weeks ago
Strategic Account Executive - Healthcare
$133K - $177K *
Join a team that's transforming healthcare by driving strategic account growth and solving complex identity challenges. Collaborate with cross-functional teams to deliver measurable outcomes and enhan...
1 week ago
Senior Program Manager - Director, Services
$150K - $175K *
Join a team that's driving transformation in insurance technology by leading complex SaaS programs. You'll ensure delivery excellence, manage risks, and enhance client confidence while shaping the fut...
1 week ago
Senior Director, Global Revenue Accounting and Order to Cash
$234K - $322K *
Transform global revenue accounting and order-to-cash processes in a dynamic healthcare environment. Lead a high-performing team, ensuring compliance with U.S. GAAP and driving systems improvements fo...
1 week ago
$140K - $180K *
Transform enterprise sales in the public sector by driving automation solutions, building strategic relationships, and generating new business opportunities while collaborating with partners and stake...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.