Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Regional Congress Account Manager
$75K - $110K *
Transform client engagement in a dynamic, detail-oriented environment. Collaborate with cross-functional teams to ensure program success and elevate customer experiences in the Life Sciences sector. D...
4 days ago
Senior Manager, Design Delivery - USA
$125K - $150K *
Accelerate progress at the forefront of AI factory design delivery, leading multidisciplinary teams to ensure successful project execution from concept to handover while balancing quality, cost, and o...
2 weeks ago
Strategic Account Executive, West
$330K - $350K *
Unlock potential by driving strategic expansion within Global 2000 accounts. Manage complex SaaS deals, collaborate with cross-functional teams, and deliver measurable business outcomes through innova...
2 weeks ago
Senior Strategic Account Executive, Private Equity Partnerships
$150K - $180K *
Empower growth by leading private equity partnerships, driving telehealth solutions across portfolios. Build relationships, negotiate agreements, and create a repeatable deployment model to enhance he...
2 weeks ago
Account Executive - New Business
$200K - $250K *
Transform your career by driving new business growth for SMBs through innovative cloud, backup, and disaster recovery solutions. Own your pipeline and strategy while collaborating with a dedicated tea...
6 days ago
Director, Consumer Digital Experience
$229K - $267K *
Innovate the consumer digital experience by leading a cross-functional team to enhance our website, mobile app, and web portal. Define a multi-year vision, prioritize initiatives, and drive engagement...
3 weeks ago
Strategic Account Executive (US East)
$100K - $120K *
Empower your career by cultivating client relationships and driving sales growth. This role focuses on renewing software subscriptions and upselling products, leveraging strategic insights to enhance...
6 days ago
Manager, Key Accounts - Data Center Materials (EMI)
$188K - $230K *
Join a team that's driving innovation in data center materials. You'll manage strategic accounts, lead complex negotiations, and collaborate with global teams to enhance customer relationships and dri...
6 days ago
Director of Product Design, Engage
$195K - $208K *
Reimagine user experiences by leading design for core product features, ensuring seamless integration and customer delight. Collaborate across teams to enhance engagement and trust, shaping the future...
3 weeks ago
Corporate Development Director
$180K - $300K *
Join a team that's driving corporate development initiatives, managing M&A processes, and collaborating with leadership to identify and execute strategic acquisitions that enhance growth and innovatio...
4 weeks ago
Strategic Account Executive, Healthcare - TOLA
$125K - $150K *
Join a team that's driving enterprise growth in healthcare across the TOLA region. Leverage your strategic selling skills to open new accounts and build executive relationships, transforming patient e...
Today
Key Account Leader, Small Cities East
$110K - $140K *
Join a dynamic team as you drive sales in the public safety sector, managing a diverse territory. Leverage AI tools to identify opportunities, close deals, and build lasting relationships with agencie...
5 days ago
Enterprise Account Executive (Founding Team)
$250K - $280K *
Shape the future of our enterprise sales segment by driving growth and account success. Take ownership of new logo acquisitions, deepen existing client relationships, and establish best practices for...
Reposted 3 weeks ago
Director, Business Transitions
$225K - $250K *
Engage with business owners navigating M&A transactions, providing integrated planning and support. Collaborate with deal teams to ensure seamless transitions and optimize after-tax outcomes during cr...
4 days ago
Account Executive, Mid Market (Midwest)
$152K - $190K *
Accelerate growth by driving IoT solutions for mid-sized customers, managing complex sales cycles, and fostering relationships with key stakeholders to deliver impactful sensor data solutions...
1 week ago
Principal Consultant - Senior SAP Account Manager
$150K - $180K *
Grow enterprise SAP relationships by managing key accounts and driving new business. Leverage your expertise to expand client portfolios, develop strategic plans, and ensure client satisfaction while...
5 days ago
$120K - $150K *
Reimagine brand identity and creative direction, leading a dynamic team to elevate packaging, campaigns, and content. Drive innovative storytelling and community experiences while collaborating across...
3 weeks ago
Administrative Business Partner, Coverage
$100K - $120K *
Support senior leaders by providing agile administrative assistance, managing complex calendars, coordinating travel, and optimizing processes to enhance operational efficiency across the organization...
4 days ago
Director, Partner Management, Americas
$195K - $241K *
Partner with us to drive growth and adoption across a diverse product portfolio, managing strategic partnerships from design to launch. Collaborate cross-functionally to enhance relationships and ensu...
1 week ago
$150K - $180K *
Unlock potential by leading enterprise sales initiatives, managing complex accounts, and driving strategic growth. You will navigate technical discussions and deliver value-driven solutions to top-tie...
4 weeks ago
Group Project Manager, Healthcare and Pharmaceutical Advertising
$120K - $150K *
Lead complex project management initiatives across multiple channels in the pharmaceutical advertising sector. Oversee cross-functional teams, ensuring timely delivery within budget while mentoring ju...
1 week ago
Enterprise Account Executive - NAMER
$135K - $185K *
Unlock potential by driving enterprise sales growth through strategic account management, leveraging industry expertise, and building strong client relationships to exceed revenue targets and enhance...
3 weeks ago
Director, Business Development
$100K - $200K *
Join a team that's driving business development across consulting, tax, and advisory services. Engage clients, build relationships, and manage the sales cycle to deliver tailored solutions and exceed...
2 weeks ago
$125K - $135K *
Lead the charge in developing and managing enterprise proposals and plans, ensuring compliance and quality across submissions. Collaborate with cross-functional teams to enhance win strategies and dri...
3 weeks ago
Associate Vice President, Group Director, Media Planning
$150K - $180K *
Optimize client strategies and drive business growth by leading integrated media planning across channels. Collaborate with cross-functional teams to translate insights into actionable recommendations...
Reposted today
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.