Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$126K - $188K *

Accelerate progress at the forefront of operational risk enablement, leading regional teams to implement enterprise standards, build capabilities, and foster relationships across diverse stakeholders...

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $140K *

Accelerate growth and expand market presence by developing strategic sales initiatives, managing national accounts, and building key industry relationships in the commercial real estate sector. Drive...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $220K *

Pioneer innovative sales strategies as you engage with clients, guiding them through the QuotaPath platform. Leverage AI tools to enhance efficiency and influence product development while driving new...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$156K - $220K *

Unlock your potential by leading the paid media strategy in a transformative role involving creative innovation and team development, driving growth through data-driven decisions across multiple chann...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Media

$150K - $180K *

Lead a high-performing sales team to drive new logo acquisition and revenue growth in enterprise software. Develop strategies, foster collaboration, and engage executive customers to expand market sha...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $125K *

Take ownership of client relationships by guiding enterprise clients through technical integrations and offering strategic insights. Leverage your expertise in digital marketing to enhance client succ...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Media

$88K - $105K *

Transform client marketing strategies by leading integrated campaigns, translating data into actionable insights, and driving measurable results. Collaborate cross-functionally while mentoring junior...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $120K *

Grow your career with a dynamic team focused on client retention and revenue growth. Drive go-to-market strategies for new products while nurturing key relationships and championing client needs in a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$100K - $170K *

Champion the growth of Audit Manager by driving sales in the healthcare sector. Leverage your expertise in medical billing and coding to engage revenue cycle leaders, manage the sales pipeline, and de...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K *

Empower public safety by driving new business in private EMS. As an Account Executive, you'll build relationships, manage sales cycles, and collaborate with teams to enhance community engagement throu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $105K *

Empower client success by managing relationships, analyzing trends, and providing strategic guidance. Lead initiatives in marketing, claims, and policy enhancements while mentoring junior staff to ens...

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$165K - $195K *

Unlock potential by leading Partner Hub advertising initiatives for enterprise hospitality clients. Drive renewals, new business, and campaign management while collaborating with cross-functional team...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $190K *

Drive strategic growth by managing key Pharma and Biotech accounts, engaging C-suite executives, and leading expansion sales processes. Collaborate cross-functionally to enhance client experiences and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Drive growth by acquiring new customers for our innovative SaaS solutions. Leverage your sales expertise to engage decision-makers, understand their needs, and promote our Amplify Platform, focusing o...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$60K - $120K *

Accelerate customer success by driving upgrades and expanding product use. In this full-cycle sales role, you'll engage with existing clients, identify opportunities, and close deals to enhance their...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Empower early-stage brands by optimizing client relationships and developing tailored marketing strategies. Guide companies through growth challenges with a focus on effective resource utilization and...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Transform financial operations by leading accounting, reporting, and FP&A. Drive efficiency through AI integration, manage audits, and build scalable processes while supporting strategic growth initia...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$80K - $120K *

Shape your career as you take ownership of key accounts, driving sales and building relationships. Collaborate with top performers to modernize government services, while gaining invaluable experience...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Join a team that's driving transformational outcomes by leading high-value sales cycles with major SLED accounts. Leverage your enterprise sales expertise to build trusted relationships and deliver im...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock your potential by driving sales of innovative Employee Comms solutions. Collaborate with partners and peers to enhance customer engagement and revenue growth while showcasing your expertise in...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $200K *

Lead the translation of investment strategies into tailored client policies, ensuring alignment with firm philosophy. Drive portfolio reviews, client communication, and advisor training while collabor...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Accelerate account management strategy and execution for premier accounts. Strengthen relationships through planning, product penetration, and high-quality execution while collaborating across teams t...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Transform airport advertising environments by conducting site visits, developing signage concepts, and collaborating with design teams. This role combines hands-on fieldwork with creative design to en...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Media

$80K - $95K *

Engage with customers to build relationships and drive sales success. Develop strategic sales plans, forecast accurately, and collaborate with teams to exceed goals while managing accounts effectively...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $140K *

Join a team that's driving sales success by engaging clients, managing opportunities, and closing deals. Leverage your expertise to present solutions and collaborate with internal teams to achieve rev...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.