Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$130K - $155K *

Lead the charge in delivering high-quality cost management services for large-scale data center projects. Collaborate with clients and stakeholders to ensure project objectives are met throughout the...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$140K - $185K *

Elevate project success by leading commissioning efforts, managing field teams, and ensuring timely execution of complex projects. Utilize advanced decision-making and client interaction skills to dri...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$90K - $100K *

Advance your career by developing impactful scientific content for diverse medical communication projects. Collaborate with cross-functional teams to translate complex data into compelling narratives...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $135K *

Collaborate with leaders to manage employee relations and complex investigations, providing expert guidance and risk assessments in a dynamic, regulated environment. Drive best practices and support w...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $104K *

Drive the full lifecycle of contractual agreements, ensuring compliance and efficiency while collaborating across teams to enhance processes and support organizational goals in a dynamic, remote-frien...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join us to drive new customer acquisition for ERP solutions in discrete manufacturing. This full-cycle sales role requires building relationships, managing complex sales processes, and achieving reven...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$320K - $360K *

Transform strategic sales through innovative leadership, cultivating executive relationships and driving revenue growth in a dynamic, high-impact environment focused on AI solutions and customer succe...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$202K - $238K *

Unlock your potential as a senior B2B marketing leader, driving strategy and demand generation. Collaborate across teams to enhance market positioning and build a high-performing marketing function th...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$150K - $180K *

Transform patient access services by leading a diverse team, managing client portfolios, and driving operational excellence to exceed performance targets while fostering strong client relationships an...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$200K - $250K *

Drive enterprise strategic planning by translating objectives into actionable priorities. Collaborate with leadership to enhance execution, accountability, and sustainable value across functions, ensu...

Reposted 3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$149K - $224K *

Drive analytics excellence by leading a team to deliver impactful insights, enhance reporting capabilities, and support strategic decision-making across diverse business functions. Foster collaboratio...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $185K *

Lead a high-performing team in business development, ensuring operational excellence and strategic alignment across the firm. Foster relationships, streamline processes, and implement innovative solut...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$105K *

Lead the charge in driving new business sales across K-12 districts, building impactful partnerships and advocating for early literacy solutions. Collaborate with internal teams to maximize outreach a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $125K *

Engage with a dynamic team to oversee copy responsibilities, crafting compelling content across various mediums. Collaborate creatively to drive engagement for diverse audiences, including healthcare...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $245K *

Lead the charge in transforming Sales Operations through innovative strategies, automation, and AI. Collaborate with clients to enhance efficiency, drive revenue, and redefine operational models for a...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$75K - $95K *

Unlock potential by navigating complex transportation claims with expertise, ensuring resolution while collaborating with clients, attorneys, and medical providers to uphold regulatory standards in a...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$140K - $185K *

Collaborate with cross-functional teams to drive product strategy, manage roadmaps, and enhance customer experiences. Lead product initiatives, ensuring alignment with business goals while mentoring j...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Advance global clinical trials by leading cross-functional teams, ensuring compliance and operational excellence while managing timelines and budgets to deliver impactful results in Oncology research...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $292K *

Shape the future of user experience by leading design across multiple products. In this strategic role, you will influence a team of designers, drive innovative product development, and elevate design...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the end-to-end recruiting process, enhancing strategies and partnerships across departments. Drive high-volume hiring with autonomy, ensuring a seamless candidate experience while collaborating c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$103K - $193K *

Drive your career by leading strategic retail media partnerships, leveraging advanced technology to optimize client success and revenue growth. Act as a consultant and SME, guiding brands through the...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$73K - $99K *

Take ownership of financial oversight and reporting for private debt funds, collaborating with diverse teams to enhance fund accounting, investor reporting, and audits, while gaining insights into com...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $145K *

Champion the future of financial reporting by ensuring compliance with GAAP, overseeing audits, and mentoring a high-performing team. Drive process improvements and technical accounting expertise to e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$97K - $133K *

Join a dynamic team to drive sales growth and enhance customer relationships. Manage key accounts, collaborate with cross-functional teams, and ensure exceptional service while achieving ambitious sal...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$127K - $171K *

Elevate marketing strategies by connecting customer insights and business goals. Develop compelling messaging and content that simplifies complex products, driving engagement and alignment across team...

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.