Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$120K - $160K *

Accelerate progress at multiple travel centers by leading operational excellence and delivering outstanding guest experiences. Drive performance and develop high-performing teams while ensuring compli...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$161K - $210K *

Elevate workforce management by leading recruitment, onboarding, and performance strategies. Drive clinician readiness and productivity while ensuring quality care through data-driven decision-making...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $245K *

Lead the charge in developing and empowering a high-performing sales team. Foster a strong team culture while driving improvement and accountability in a rapidly changing environment, leveraging data...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$160K - $203K *

Drive impactful legal solutions by drafting and negotiating complex data contracts. Collaborate with cross-functional teams to support growth while managing risk in a fast-paced environment focused on...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Transform client relationships as you deliver elite service and expert risk management for high-net-worth clients. Drive retention and growth through proactive consulting and strategic market placemen...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Drive enterprise growth by selling data security solutions, building relationships with IT leaders, and executing strategic territory plans. This role demands a proactive approach to generate pipeline...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$274K - $371K *

Lead the early phase clinical development of innovative therapeutics, collaborating across teams to design and execute trials. Your expertise will directly influence strategy, protocol development, an...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead hotel operations to deliver exceptional guest experiences, optimize resources, and drive financial performance. Collaborate across departments to enhance service quality and ensure compliance wit...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$116K - $194K *

Elevate your career by joining a dynamic engineering team focused on ATM and TCR technologies. As a key technical specialist, you'll enhance customer-facing banking services through innovative solutio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $140K *

Transform global client relationships by driving revenue growth and strategic account management. Collaborate with C-suite executives to connect workplace culture and employee experience to measurable...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $145K *

Empower enterprise growth by managing high-value accounts in a dynamic SaaS environment. Drive the full sales cycle, build executive relationships, and navigate complex negotiations to achieve impactf...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$175K - $210K *

Join as a strategic leader in Revenue Operations, driving growth initiatives and optimizing performance for a $750M+ Business Unit. Collaborate with executive teams to enhance revenue strategies, fore...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$180K - $200K *

Elevate your career by driving growth strategies that enhance lead generation for multiple brands. Collaborate with cross-functional teams to optimize acquisition channels and improve conversion rates...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $160K *

Transform real estate opportunities by leading market evaluations, strategic planning, and cross-functional collaboration to optimize portfolio growth and cost management across multiple regions...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Drive impactful scientific communication by overseeing content development across therapeutic areas, ensuring strategic alignment with client goals while managing a team and collaborating with various...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$140K - $175K *

Lead transformative insurance program initiatives, overseeing technology enhancements and operational workflows. Collaborate across teams to drive project management and ensure compliance, while optim...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Empower your career by serving as a legal partner in procurement and supply chain, providing expert guidance and support in contract negotiation, vendor relations, and operational risk management acro...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$100K - $120K *

Drive operational excellence as a trusted advisor, managing high-impact client accounts to translate complex data into strategic insights, guiding executive decision-making, and fostering client relat...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $115K *

Help us drive client success by managing digital brand strategies and fostering strong relationships. Leverage your expertise in pharmaceutical marketing to deliver innovative solutions and ensure pro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $165K *

Partner with us to drive strategic growth by providing expert legal guidance on commercial contracts, balancing risk and business objectives while collaborating with cross-functional teams to support...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $181K *

Drive innovation by leading the design and optimization of scalable data pipelines and platforms. Collaborate with teams to ensure high-quality data solutions while mentoring engineers and guiding com...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $185K *

Elevate your career by leading a dynamic sales organization across North and Latin America. Drive revenue growth, develop high-performing teams, and implement strategic processes for sustainable succe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $140K *

Transform regional accounts by developing strategic programs and building strong relationships with local decision-makers. Drive growth through effective budgeting, insights, and innovative solutions...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$153K - $258K *

Lead the charge in enhancing digital product management practices, driving strategic alignment, and fostering cross-functional collaboration to deliver impactful customer and business outcomes across...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Drive financial strategy and execution for new business and client retention in the Higher Education Sector, optimizing revenue and profitability while collaborating with cross-functional teams to ens...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.